Resorcinol diglycidyl ether - ≥94% , CAS No.101-90-6

CAS: 101-90-6 Cat. No.: R131840 Molecular Weight: 222.24 EC Number: 202-987-5 PubChem CID: 7586

GRADE & PURITY ≥94%

Synonyms

1,3-BIS(2,3-EPOXYPROPOXY)BENZENE [HSDB] | meta-Bis(glycidyloxy)benzene | RDGE | Diglycidylresorcinol ether | NCGC00091808-01 | 1,3-Diglycidyloxybenzene | 2,2'-(1,3-Phenylenebis(oxymethylene)bisoxirane) | NCIOpen2_003997 | Resorcinol bis(2,3-epoxypropyl) e

Storage

Argon charged,Room temperature

Shipped In

Normal

Overview

Reactive diluent and modifier in epoxy resins used in coatings, potting and tooling compounds, adhesives and composites.

Specifications

Synonyms

1, 3-BIS(2, 3-EPOXYPROPOXY)BENZENE [HSDB] | meta-Bis(glycidyloxy)benzene | RDGE | Diglycidylresorcinol ether | NCGC00091808-01 | 1, 3-Diglycidyloxybenzene | 2, 2'-(1, 3-Phenylenebis(oxymethylene)bisoxirane) | NCIOpen2_003997 | Resorcinol bis(2, 3-epoxypropyl) e

Specifications & Purity

≥94%

Storage

Argon charged, Room temperature

Shipped In

Normal

Purity

≥94%

Names and Identifiers

• Pubchem Sid: 488180495
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488180495
• Canonical Smiles: C1C(O1)COC2=CC(=CC=C2)OCC3CO3
• IUPAC Name: 2-[[3-(oxiran-2-ylmethoxy)phenoxy]methyl]oxirane
• InChIKey: WPYCRFCQABTEKC-UHFFFAOYSA-N
• INCHI: 1S/C12H14O4/c1-2-9(13-5-11-7-15-11)4-10(3-1)14-6-12-8-16-12/h1-4,11-12H,5-8H2
• Isomeric SMILES: C1C(O1)COC2=CC(=CC=C2)OCC3CO3
• WGK Germany: 2
• RTECS: VH1050000
• PubChem CID: 7586
• UN Number: 2811
• Packing Group: I
• Molecular Weight: 222.24

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Class Phenol ethers

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Class: Phenol ethers
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Phenol ethers
• Alternative Parents: Phenoxy compounds Alkyl aryl ethers Oxacyclic compounds Epoxides Dialkyl ethers Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Phenoxy compound - Phenol ether - Alkyl aryl ether - Monocyclic benzene moiety - Oxacycle - Organoheterocyclic compound - Ether - Oxirane - Dialkyl ether - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring.
• External Descriptors: aromatic ether

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

ESR1 Tclin Estrogen receptor alpha (17718 Activities)

Discover Target: ESR1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NR3C1 Tclin Glucocorticoid receptor (14987 Activities)

Discover Target: NR3C1

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AR Tclin Androgen Receptor (11781 Activities)

Discover Target: AR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

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TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

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PPARG Tclin Peroxisome proliferator-activated receptor gamma (15191 Activities)

Discover Target: PPARG

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THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

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RXRA Tclin Retinoid X receptor alpha (3637 Activities)

Discover Target: RXRA

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CXCL8 Tchem Interleukin-8 (642 Activities)

Discover Target: CXCL8

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

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NR1H4 Tclin Bile acid receptor FXR (6228 Activities)

Discover Target: NR1H4

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CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

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TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

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Lymphoblastoid cell (5959 Activities)

Explore this target

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HIF1A Tchem Hypoxia-inducible factor 1 alpha (6027 Activities)

Discover Target: HIF1A

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APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

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Associated Targets(non-human)

Ppard Peroxisome proliferator-activated receptor delta (358 Activities)

Discover Target: Ppard

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lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

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Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)

Discover Target: Nfe2l2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Rorc Nuclear receptor ROR-gamma (89407 Activities)

Discover Target: Rorc

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Mechanisms of Action

Chemical and Physical Properties

• Solubility: Insoluble in water.
• Sensitivity: Hygroscopic
• Refractive Index: 1.542 (lit.)
• Flash Point(°F): 235.4 °F
• Flash Point(°C): 113 °C
• Boil Point(°C): 172 °C (lit.)
• Melt Point(°C): 33-35℃
• Molecular Weight: 222.240 g/mol
• XLogP3: 1.200
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 222.089 Da
• Monoisotopic Mass: 222.089 Da
• Topological Polar Surface Area: 43.500 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 211.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 2
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Jinyi Liu, Haojie Yu, Li Wang, Sergey Z. Vatsadze, Dingning Chen, Xudong Wu, Xiaodan Gong, Yu Wang.  (2023)  One-step synthesis of ferrocenyl glycidyl ethers as combustion catalysts for the thermal decomposition of ammonium perchlorate.  POWDER TECHNOLOGY,      [PMID:] [10.1016/j.powtec.2023.118772]

2. Xiaoli Ren, Xiujun Wang, Jian Zhang, Ming Duan, Yan Xiong, Shenwen Fang, Man Shi.  (2023)  Synthesis of branched cationic flocculant and its performance in treating industrial wastewater with different compositions.  Journal of Water Process Engineering,      [PMID:] [10.1016/j.jwpe.2023.103824]

3. Xiankun Wu, Chang-an Xu, Mangeng Lu, Xiaole Zheng, Yingjie Zhan, Bifang Chen, Kunxin Wang, Huifa Meng.  (2022)  Preparation and characterization of a low viscosity epoxy resin derived from m-divinylbenzene.  HIGH PERFORMANCE POLYMERS,      [PMID:] [10.1177/09540083221097380]

4. Meng-Dan Gong, Xin-Jiang Pei, Guang-Xu Duan, Gao-Ying Zhi, Zhi-Qin Liu, Dong-Hao Zhang.  (2022)  Molecular cages encapsulating lipase and the effect of cage hydrophobicity and cage size.  MATERIALS & DESIGN,      [PMID:] [10.1016/j.matdes.2022.110865]

5. Junyu Chu, Heng Wang, Yiwen Zhang, Zhengkai Li, Zhencai Zhang, Hongyan He, Qinqin Zhang, Fei Xu.  (2021)  Design and synthesis of gradient-refractive index isosorbide-based polycarbonates for optical uses.  REACTIVE & FUNCTIONAL POLYMERS,      [PMID:] [10.1016/j.reactfunctpolym.2021.105145]

6. Xianghui Dai, Xia Yu, Jian Zheng, Xiaoxu Yang, Jianjun Pan, Xiaoting Zhang, Jie Min.  (2021)  A kelp-inspired polyester fabric surface of UV grafted hydrogel for drag reduction.  JOURNAL OF APPLIED POLYMER SCIENCE,  139  (7): (51634).  [PMID:] [10.1002/app.51634]

7. Zhipeng Ran, Yeping Wu, Mao Chen, Yinyu Zhang, Peishuang Xiao, Keping Chen, Xiuli Zhao.  (2026)  A Chemical Timer Triggered by Autonomous ‘pH’ Evolution for Thiol-Epoxy Click Reactions.  THERMOCHIMICA ACTA,      [PMID:] [10.1016/j.tca.2026.180288]

8. Zhe Zhang, Dong Yue, Jian Wang, Qixin Yuan, Yuanhang Yao, Wenchao Zhang, Zhou Yang, Qiang Fu, Yu Feng.  (2026)  Synergistic improvement of rheological, thermal conductive, and dielectric properties for epoxy resin composites based on active organic small molecules and inorganic fillers.  Applied Materials Today,      [PMID:] [10.1016/j.apmt.2026.103229]