10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Seladelpar sodium salt (MBX-8025) is an orally active, potent and specific PPARδ agonist with an EC 50 of 2 nM, showing more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively.
IC50& Target:PPAR-δ 2 nM (EC 50 )
In Vitro:MBX-8025 is an orally active, potent (EC 50 =2 nM), and specific (750-fold and 2500-fold compared with PPARα or PPARγ receptors, respectively) PPARδ agonist being developed as a lipid-altering agent [2]. MCE has not independently confirmed the accura
In Vivo:In atherogenic diet-fed Wt mice, administration of Seladelpar sodium salt reduces body weight by ~18% (P<0.05). In contrast, Seladelpar sodium salt produces minimal effect on body weight in atherogenic diet-fed foz/foz mice. Seladelpar sodium salt lowers
Biological Activity:Seladelpar sodium salt (MBX-8025) is an orally active, potent and specific PPARδ agonist with an EC 50 of 2 nM, showing more than 750-fold and 2500-fold selectivity over the PPARα and PPARγ receptors, respectively.
| Canonical Smiles | O=C(O[Na])COC1=CC=C(SC[C@H](OCC)COC2=CC=C(C(F)(F)F)C=C2)C=C1C |
|---|---|
| Molecular Weight | 466.45 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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