Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 45 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Thiosemicarbazide is a vitamin B6 antagonist with anti-acne activity. Thiosemicarbazide is also a well-known source in the synthesis of heterocycles, and its derivatives have potential anticancer activity. Thiosemicarbazide (TSC: HL1) reacts with metal salts, urea (U), to prepare Co(II) and Cu(I) metal complexes. Thiosemicarbazide is also used in the fields of media communications and optical storage, and in the spectrophotometric detection of metals .
| Isomeric SMILES | C(=S)(N)NN |
|---|---|
| WGK Germany | 3 |
| RTECS | VT4200000 |
| PubChem CID | 2723789 |
| UN Number | 2811 |
| Packing Group | I |
| Molecular Weight | 91.14 |
| Beilstein | 506320 |
| Reaxy-Rn | 506320 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Melt Point(°C) | 180-181°C |
|---|
| 1. Yuhou Pei, Di Li, Yufeng Pei, Zongmiao Li, Yuting Liu, Xiang Ling, Yingying Lu, Bing Zhang. (2025) Tailoring the triple-phase microenvironment for kinetically matched C-N coupling in urea electrosynthesis. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2025.125939] |
| 2. Zhuo Wang, Rulin Li, Donghao Jiao, Qijun Cheng, Zitong Yang, Jiayi Xu, Chenhuinan Wei. (2025) Post-modification of zirconium based metal-organic frameworks for efficient and selective gold adsorption in wastewater. MICROPOROUS AND MESOPOROUS MATERIALS, [PMID:] [10.1016/j.micromeso.2025.113867] |
| 3. Yanli He, Shuguang Shen, Ying Wang, Chenyuan Guo, Yaping Yuan, Yaru Fan, Lili Zhang, Yuyan Song. (2023) Simple and efficient strategy for α-MnO2/C by in-situ synthesis and its performance for degrading urea process wastewater. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2023.110303] |
| 4. Xianyong Zhou, Xiangfeng Luan, Luozheng Zhang, Hang Hu, Zhengyan Jiang, Yaru Li, Jiawen Wu, Yanliang Liu, Jiabang Chen, Deng Wang, Chang Liu, Shi Chen, Yong Zhang, Meiqing Zhang, Yuanjun Peng, Pavel A. Troshin, Xingzhu Wang, Yiyong Mai, Baomin Xu. (2023) Dual Optimization of Bulk and Interface via the Synergistic Effect of Ligand Anchoring and Hole Transport Dopant Enables 23.28% Efficiency Inverted Perovskite Solar Cells. ACS Nano, [PMID:36779831] [10.1021/acsnano.2c11615] |
| 5. Zhihua Shen, Jialiang Chen, Gefei Li, Gaohua Situ, Xiaofeng Ma, Ye Sha, Dong Zhao, Qun Gu, Meng Zhang, Yanlong Luo, Zhenyang Luo. (2022) Mechanically robust self-repairing polyurea elastomers: The roles of hard segment content and ordered/disordered hydrogen-bonding arrays. EUROPEAN POLYMER JOURNAL, [PMID:] [10.1016/j.eurpolymj.2022.111657] |
| 6. Yanmei Huang, Yuting Wang, Yang Liu, Aijing Ma, Jianzhou Gui, Chaoxin Zhang, Yifu Yu, Bin Zhang. (2022) Unveiling the quantification minefield in electrocatalytic urea synthesis. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2022.139836] |
| 7. Xinying Duan, Li Zhang, Hongyan Si, Jie Song, Peng Wang, Shangxing Chen, Hai Luo, Xiaoping Rao, Zongde Wang, Shengliang Liao. (2022) Synthesis, Antifungal Activity, Cytotoxicity and QSAR Study of Camphor Derivatives. Journal of Fungi, 8 (8): (762). [PMID:35893130] [10.3390/jof8080762] |
| 8. Chunfeng Shao, Lingmin Wu, Yinghua Wang, Konggang Qu, Hailiang Chu, Lixian Sun, Jianshan Ye, Baitao Li, Xiujun Wang. (2022) Engineering asymmetric Fe coordination centers with hydroxyl adsorption for efficient and durable oxygen reduction catalysis. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2022.121607] |
| 9. Pei Jia, Jiayu Yang, Jinjie Hou, Kairong Yang, Taotao Zhe, Tong Bu, Li Wang. (2021) Innovative ratiometric optical strategy: Nonconjugated polymer dots based fluorescence-scattering dual signal output for sensing mercury ions. FOOD CHEMISTRY, [PMID:34894467] [10.1016/j.foodchem.2021.131771] |
| 10. Feifei Xu, Jianghong Zhao, Jianlong Wang, Taotao Guan, Kaixi Li. (2021) Strong coordination ability of sulfur with cobalt for facilitating scale-up synthesis of Co9S8 encapsulated S, N co-doped carbon as a trifunctional electrocatalyst for oxygen reduction reaction, oxygen and hydrogen evolution reaction. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:34794809] [10.1016/j.jcis.2021.10.182] |
| 11. Yifan Liu, Ruihan Pei, Yuancai Lv, Chunxiang Lin, Jianhui Huang, Minghua Liu. (2021) Removal behavior and mechanism of silver from low concentration wastewater using cellulose aerogel modified by thiosemicarbazide. JOURNAL OF APPLIED POLYMER SCIENCE, 138 (42): (51226). [PMID:] [10.1002/app.51226] |
| 12. Chenyuan Guo, Shuguang Shen, Meina Li, Ying Wang, Jing Li, Yuanquan Xing, Cui Wang, Huajie Pan. (2020) Rapid in situ synthesis of MgAl-LDH on η-Al2O3 for efficient hydrolysis of urea in wastewater. JOURNAL OF CATALYSIS, [PMID:] [10.1016/j.jcat.2020.12.024] |
| 13. Yiying Yue, Jiamin Gu, Jingquan Han, Qinglin Wu, Jianchun Jiang. (2020) Effects of cellulose/salicylaldehyde thiosemicarbazone complexes on PVA based hydrogels: Portable, reusable, and high-precision luminescence sensing of Cu2+. JOURNAL OF HAZARDOUS MATERIALS, [PMID:33113738] [10.1016/j.jhazmat.2020.123798] |
| 14. Pei Ruihan, Li Qiqi, Liu Jianting, Yang Guifang, Wu Qiong, Wu Minya, Tong Shengxuan, Lv Yuancai, Ye Xiaoxia, Liu Yifan, Liu Minghua. (2020) Adsorption/Reduction Behaviors of Modified Cellulose Aerogels for the Removal of Low Content of Cr(VI). JOURNAL OF POLYMERS AND THE ENVIRONMENT, 28 (8): (2199-2210). [PMID:] [10.1007/s10924-020-01761-4] |
| 15. Shuoran Chen, Fuming Chen, Pengju Han, Changqing Ye, Suqin Huang, Lei Xu, Xiaomei Wang, Yanlin Song. (2019) A stimuli responsive triplet–triplet annihilation upconversion system and its application as a ratiometric sensor for Fe3+ ions. RSC Advances, 9 (62): (36410-36415). [PMID:35540611] [10.1039/C9RA06524E] |
| 16. Yongshun Gao, Shuo Zhang, Wenlong Hou, Huiyun Guo, Qizhe Li, Danyang Dong, Siyu Wu, Shiyuan Zhao, Haiquan Zhang. (2019) Perylene diimide derivative regulate the antimony sulfide morphology and electrochemical sensing for hydrazine. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2019.06.149] |
| 17. Wang Ying, Shen Shuguang, Li Meina, Sun Yujuan, Li Binbin. (2018) In Situ Growth of Highly Active MgAl Layered Double Hydroxide on η-Al2O3 for Catalytic Hydrolysis of Urea in Wastewater. CATALYSIS LETTERS, 148 (7): (1893-1903). [PMID:] [10.1007/s10562-018-2387-3] |
| 18. Guo Lin, Shixing Wang, Libo Zhang, Tu Hu, Jinhui Peng, Song Cheng, Likang Fu. (2018) Synthesis and evaluation of thiosemicarbazide functionalized corn bract for selective and efficient adsorption of Au(III) from aqueous solutions. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2018.03.030] |
| 19. Gengwei Zhang, Yang Zhou, Zhao Ding, Likang Fu, Shixing Wang. (2017) Nanosilica-supported thiosemicarbazide–glutaraldehyde polymer for selective Au(III) removal from aqueous solution. RSC Advances, 7 (87): (55215-55223). [PMID:] [10.1039/C7RA10199F] |
| 20. Yue-cheng Lin, Hong-peng Wang, Faryal Gohar, Muhammad Haseeb Ullah, Xiang Zhang, Dong-fang Xie, Hui Fang, Jun Huang, Jun-xing Yang. (2016) Preparation and copper ions adsorption properties of thiosemicarbazide chitosan from squid pens. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:27889339] [10.1016/j.ijbiomac.2016.11.085] |
| 21. Zheng Fu, Fengling Cui. (2016) Thiosemicarbazide chemical functionalized carbon dots as a fluorescent nanosensor for sensing Cu2+ and intracellular imaging. RSC Advances, 6 (68): (63681-63688). [PMID:] [10.1039/C6RA10168B] |
| 22. Gao Minggang, Yang Liu, Dai Bin, Guo Xuhong, Liu Zhiyong, Peng Banghua. (2016) A novel Ni-Schiff base complex derived electrocatalyst for oxygen evolution reaction. JOURNAL OF SOLID STATE ELECTROCHEMISTRY, 20 (10): (2737-2747). [PMID:] [10.1007/s10008-016-3279-3] |
| 23. Sheng Deng, Peng Wang, Guangshan Zhang, Yuan Dou. (2016) Polyacrylonitrile-based fiber modified with thiosemicarbazide by microwave irradiation and its adsorption behavior for Cd(II) and Pb(II). JOURNAL OF HAZARDOUS MATERIALS, [PMID:26775107] [10.1016/j.jhazmat.2016.01.002] |
| 24. Liu Heng, Ding Hui, Zhu Lili, Wang Yue, Chen Zili, Tian Zhiyuan. (2015) A Indole-Trizole-Rhodamine Triad as Ratiometric Fluorescent Probe for Nanomolar-Concentration Level Hg2+ Sensing with High Selectivity. JOURNAL OF FLUORESCENCE, 25 (5): (1259-1266). [PMID:26179076] [10.1007/s10895-015-1614-1] |
| 25. Chiyao Bai, Meicheng Zhang, Bo Li, Yin Tian, Shuang Zhang, Xiaosheng Zhao, Yang Li, Lei Wang, Lijian Ma, Shoujian Li. (2015) Three novel triazine-based materials with different O/S/N set of donor atoms: One-step preparation and comparison of their capability in selective separation of uranium. JOURNAL OF HAZARDOUS MATERIALS, [PMID:26218304] [10.1016/j.jhazmat.2015.07.020] |
| 26. Shen Shuguang, Li Meina, Li Binbin, Zhao Zhijun. (2014) Catalytic hydrolysis of urea from wastewater using different aluminas by a fixed bed reactor. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 21 (21): (12563-12568). [PMID:24952253] [10.1007/s11356-014-3189-9] |
| 27. Xin Zhong, Huiping Zhao, Hao Yang, Yunling Liu, Guoping Yan, Rong Chen. (2013) Tunable surface wettability and water adhesion of Sb2S3 micro-/nanorod films. APPLIED SURFACE SCIENCE, [PMID:] [10.1016/j.apsusc.2013.10.179] |
| 28. Cao Ben-nan, Hu Qin, Huang Yan, Jia Chun-man, Zhang Qi. (2013) Highly sensitive and selective chemosensor for Cu2+ based on a Schiff base. CHEMICAL RESEARCH IN CHINESE UNIVERSITIES, 29 (3): (419-423). [PMID:] [10.1007/s40242-013-2449-4] |
| 29. Zhenning Yan, Shuangqiang Wang, Haixia Wang, Shuangyan Wu. (2013) Bismuth (III) PVC membrane ion selective electrodes based on two compounds: Acylhydrazone and thiosemicarbazone with 1,3,4-thiadiazole. Materials Science & Engineering C-Materials for Biological Applications, [PMID:23623069] [10.1016/j.msec.2013.02.017] |
| 30. Wei Lu, Dan Chen, Han Jiang, Liming Jiang, Zhiquan Shen. (2011) Polymer-based fluoride-selective chemosensor: Synthesis, sensing property, and its use for the design of molecular-scale logic devices. JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY, 50 (3): (590-598). [PMID:] [10.1002/pola.25068] |
| 31. Yanping Li, Haoran Liu, Ronghao Fang, Jiamin Jin, Feng Yang, Jian Chen, Juzheng Zhang. (2024) Designing novel Au(III) complexes based on the structure of diazepam: Achieving a multiaction mechanism against glioma. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, [PMID:39705733] [10.1016/j.ejmech.2024.117171] |
| 32. Huang Da-Shuai, Qiu Xiao-Feng, Huang Jia-Run, Mao Min, Liu Lingmei, Han Yu, Zhao Zhen-Hua, Liao Pei-Qin, Chen Xiao-Ming. (2024) Electrosynthesis of urea by using Fe2O3 nanoparticles encapsulated in a conductive metal–organic framework. Nature Synthesis, [PMID:] [10.1038/s44160-024-00603-8] |
| 33. Zhiyun Peng, Jinfeng Zhang, Min He, Guangcheng Wang. (2024) Inhibitory activity and mechanism of thiosemicarbazide derivatives on tyrosinase and their anti-browning activity in fresh apple juice. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39284471] [10.1016/j.ijbiomac.2024.135631] |
| 34. Yichun Lou, Haoyu Chen, Linrui Wang, Shengpeng Chen, Yameng Song, Yifei Ding, Zixiang Hao, Chengli He, Dong Qiu, Hui Li, Junjian Wang, Duanyang Liu, Xiaoli Cui. (2025) Mechanochemical Urea Synthesis Using Ammonia–Water and Carbon Dioxide Under Mild Conditions: An Experimental and Theoretical Study. ACS Sustainable Chemistry & Engineering, [PMID:] [10.1021/acssuschemeng.4c05811] |
| 35. Lingjia Ma, Jiongliang Yuan, Zhaotao Liu, Yiqing Luo, Yuning Su, Kunye Zhu, Zefeng Feng, Huihua Niu, Shuaishuai Xiao, Jianjun Wei, Xu Xiang. (2024) Mesoporous Electrocatalysts with p–n Heterojunctions for Efficient Electroreduction of CO2 and N2 to Urea. ACS Applied Materials & Interfaces, [PMID:38721726] [10.1021/acsami.4c00257] |
| 36. Jia-Yi Luo, Zhao-Jing Huang, Ming Zhao, Shunxing Li, Fengying Zheng, Xuguang Huang, Fengjiao Liu, Luxiu Lin, Zheng Bin Huang, Haijiao Xie. (2024) One-to-Nine Single Spectroscopic Intelligent Probe for Risk Assessment of Multiple Metals in Drinking Water. ANALYTICAL CHEMISTRY, [PMID:38953489] [10.1021/acs.analchem.4c02181] |
| 37. Yanan Wang, Dongxu Chen, Xueyan Xue, Aikelaimu Aihemaiti, Jiao Yin, Hui Zhu. (2024) Surface functionalized biochar for the effective capacitive deionization of lead ions. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2024.127907] |
| 38. Yu Zhu, Ying Wang, Huimin Zhao, Jinli Wei, Haoyuan Chen, Maroosha Javed, Linghua Zhuang, Guowei Wang. (2025) Synthesis, antioxidant activity, DFT simulations, molecular docking studies of Schiff base derivatives containing 2-(2-hydrazinyl) thiazole moiety. JOURNAL OF MOLECULAR STRUCTURE, [PMID:] [10.1016/j.molstruc.2025.142150] |
| 39. Yanlin Lv, Lili Zhu, Heng Liu, Yishi Wu, Zili Chen, Hongbing Fu, Zhiyuan Tian. (2014) Single-fluorophore-based fluorescent probes enable dual-channel detection of Ag+ and Hg2+ with high selectivity and sensitivity. ANALYTICA CHIMICA ACTA, [PMID:25066721] [10.1016/j.aca.2014.06.010] |
| 40. Xue Wang, Lu-Kang Zhao, Si-Yao Li, Ran Wei, Xuanwen Gao, Zhaomeng Liu, Wenbin Luo. (2025) Co-reduction Coupling of Bicarbonate and Nitrate toward Efficient Urea Synthesis. Nanoscale, [PMID:40104997] [10.1039/D4NR05196C] |
| 41. Youcai Meng, Tianran Wei, Zhiwei Wang, Caiyun Wang, Junyang Ding, Yang Luo, Xijun Liu. (2025) Bimetallic Copper–Indium Co-Doped Titanium Dioxide Towards Electrosynthesis of Urea from Carbon Dioxide and Nitrate. C-Journal of Carbon Research, 11 (3): (44). [PMID:] [10.3390/c11030044] |
| 42. Zhao-Yun Wang, Li-Xin Yu, Yu-Qing Feng, Lei Jin, Jia-Qiang Yang, Yi Zhao, Tao Song, DongPing Zhan, Daquan Yu, Fang-Zu Yang, Shi-Gang Sun. (2025) Study on the Action Mechanism of a Nontraditional Thioamide-Based Leveler of 1-Phenyl 2-Thiourea for Microvia Void-Free Filling. ACS Applied Materials & Interfaces, [PMID:40262106] [10.1021/acsami.5c04034] |
| 43. Jinwei Tian, Yao Wei, Chengwei Lü. (2025) 1,3,4-Thiadiazole and quinolinone based multifunctional probes for fluorescence turn-on and colorimetric monitoring of Al3+ and Fe3+ in food and aqueous environment applications. FOOD CHEMISTRY, [PMID:41485311] [10.1016/j.foodchem.2025.147792] |
| 44. Liming Xiao, Fangyuan Yu, Ping Sun, Xiaodong Wang, Linmao Wen, Yunzi Ren, Feng Cao, Jun Mao, Qian Zhang. (2026) High-Performance Tailored Ag 2 Se Thermoelectric Networks via Electrodeposition for Body Heat Recovery. Journal of Materials Chemistry A, [PMID:] [10.1039/D5TA09696K] |
| 45. Xin Xin, Qi Zhang, Sujun Yan, Zilong Chen, Xinhai Zhu. (2026) Ultrasensitive LC-MS analysis of saccharides using 2-hydrazinyl-6-methoxy-1,3-benzothiazole as a novel derivatization reagent. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2026.117921] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
