Validamycin A - Moligand™, 10 mM in Water , CAS No.37248-47-8

CAS: 37248-47-8 Cat. No.: V1499435 Molecular Weight: 497.51 EC Number: 609-372-4 PubChem CID: 443629

GRADE & PURITY Moligand™, 10 mM in Water

Storage

Protected from light,Argon charged,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Validamycin A, a fungicidal, is an agricultural antibiotic . Validamycin A is originally isolated from Streptomyces hygroscopicus var. limoneus . Validamycin A inhibits the growth of A. flavus , with a MIC of 1 μg/mL. Validamycin A shows potent inhibitory activity against trehalase of Rhizoctonia solani , with an IC 50 of 72 μM. Validamycin A is a reversible tyrosinase inhibitor, with a K i of 5.893 mM.

Specifications

Specifications & Purity

Moligand™, 10 mM in Water

Storage

Protected from light, Argon charged, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: C1[C@@H]([C@H]([C@@H]([C@H]([C@H]1N[C@H]2C=C([C@H]([C@@H]([C@H]2O)O)O)CO)O)O)O[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)CO
• PubChem CID: 443629
• Molecular Weight: 497.51

Chemical and Physical Properties

• Melt Point(°C): 130-135°C

References

1. Tingting Li, Qin Wang, Yan Yang, Dingka Song.  (2023)  The mechanism of polysaccharide synthesis of Sanghuangporus sanghuang based on multi-omic analyses and feedback inhibition.  CARBOHYDRATE POLYMERS,      [PMID:37739500] [10.1016/j.carbpol.2023.121288]

2. Yan Song, Fengming Gu, Yijiangcheng Li, Weihong Zhou, Fu-an Wu, Jun Wang, Sheng Sheng.  (2023)  Host trehalose metabolism disruption by validamycin A results in reduced fitness of parasitoid offspring.  PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY,      [PMID:37666623] [10.1016/j.pestbp.2023.105570]