Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 3 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Vinpocetine (Ethyl apovincaminate) is a derivative of the alkaloid Vincamine that blocks voltage-gated Na + channels. The IC 50 value of Vinpocetine on direct IKK inhibition in the cell-free system is 17.17 μM. Vinpocetine is a phosphodiesterase (PDE) inhibitor and inhibits NF-κB -dependent inflammatory responses by directly targeting IκB kinase complex ( IKK ) , and has been widely used for the treatment of cerebrovascular disorders.
| Isomeric SMILES | CC[C@@]12CCCN3[C@@H]1C4=C(CC3)C5=CC=CC=C5N4C(=C2)C(=O)OCC |
|---|---|
| WGK Germany | 3 |
| RTECS | JW4792000 |
| PubChem CID | 443955 |
| Molecular Weight | 350.45 |
| Reaxy-Rn | 900803 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Specific Rotation[α] | 118° (C=2,Pyridine) |
|---|---|
| Melt Point(°C) | 151 °C |
| 1. Chong Zhang, Zuoyan Zhang, Yueyi Wu, Yuchen Wu, Jing Cheng, Kaizhi Luo, Zhidi Li, Manman Zhang, Jian Wang, Xuesen Zhang, Yangling Li. (2025) Phosphodiesterase 1A physically interacts with YTHDF2 and reinforces the progression of non-small cell lung cancer. eLife, [PMID:40704992] [10.7554/eLife.98903] |
| 2. Zhang Zuo-yan, Dong Shu-min, Liu Ye-han, Zhang Man-man, Zhang Jian-kang, Zhu Hua-jian, Shao Jia-an, Liu Hua-qing, Li Yang-ling, Zhang Chong, Zeng Ling-hui. (2021) Enhanced anticancer activity by the combination of vinpocetine and sorafenib via PI3K/AKT/GSK-3β signaling axis in hepatocellular carcinoma cells. ANTI-CANCER DRUGS, 32 (7): (727). [PMID:33735117] [10.1097/CAD.0000000000001056] |
| 3. Shengzheng Guo, Yuechao Cao, Yuxin Zhang, Yan Wang, Zhenguo Gao, Junbo Gong. (2024) A Scalable Freeze-Dissolving Approach to Prepare Ultrafine Crystals for Inhalation: Mechanism and Validation. CRYSTAL GROWTH & DESIGN, [PMID:] [10.1021/acs.cgd.4c00018] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →
