2′-Deoxy-2′-fluoroadenosine - Moligand™, 10 mM in DMSO , CAS No.64183-27-3

CAS: 64183-27-3 Cat. No.: D1500707 Molecular Weight: 269.24 EC Number: 814-045-6

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Argon charged,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

2′-Deoxy-2′-fluoroadenosine can be used for the synthesis of 2′-Deoxy-2′-fluoro-modified oligonucleotides hybridized with RNA. 2′-Deoxy-2′-fluoroadenosine can be cleaved efficiently by E. coli purine nucleoside phosphorylase (PNP) to the toxic agent 2-fluoroadenine (FAde). 2′-Deoxy-2′-fluoroadenosine shows excellent in vivo activity against tumors expressing E. coli PNP.

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Argon charged, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)F)N
• Molecular Weight: 269.24
• Reaxy-Rn: 24737949
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24737949&ln=

Chemical and Physical Properties

• Melt Point(°C): 228 -231°C