cis-Diammineplatinum dichloride - Moligand™, Pt,65% , CAS No.15663-27-1

CAS: 15663-27-1 Cat. No.: D109812 Molecular Weight: 300.1 EC Number: 239-733-8

GRADE & PURITY Moligand™, Pt,65%

Synonyms

Cisplatin

Storage

Protected from light,Room temperature,Argon charged,Desiccated,Cool

Shipped In

Normal

Specifications

Synonyms

Cisplatin

Specifications & Purity

Moligand™, Pt, 65%

Biochemical and Physiological Mechanisms

Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links.Potent, broad spectrum antineoplastic agent. Cytotoxic, crosslinks DNA to impair replication and transcription. Arrests cell cycle in G 2 /M phase. Antitumor, cros

Storage

Protected from light, Room temperature, Argon charged, Desiccated, Cool

Shipped In

Normal

Grade

Moligand™

Note

Unstable; make up solutions fresh and use immediately. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Names and Identifiers

• Canonical Smiles: N.N.Cl[Pt]Cl
• InChIKey: LXZZYRPGZAFOLE-UHFFFAOYSA-L
• INCHI: 1S/2ClH.2H3N.Pt/h2*1H;2*1H3;/q;;;;+2/p-2
• WGK Germany: 3
• RTECS: TP2450000
• UN Number: 2928
• Packing Group: I
• Molecular Weight: 300.1

Taxonomic Classification

Taxonomy Tree

• Kingdom Inorganic compounds
  • Superclass Mixed metal/non-metal compounds
    • Class Transition metal salts
      • Subclass Transition metal chlorides

• Kingdom: Inorganic compounds
• Superclass: Mixed metal/non-metal compounds
• Class: Transition metal salts
• Subclass: Transition metal chlorides
• Intermediate Tree Nodes: Not available
• Direct Parent: Transition metal chlorides
• Alternative Parents: Inorganic chloride salts
• Molecular Framework: Not available
• Substituents: Transition metal chloride - Inorganic chloride salt - Inorganic salt
• Description: This compound belongs to the class of inorganic compounds known as transition metal chlorides. These are inorganic compounds in which the largest halogen atom is Chlorine, and the heaviest metal atom is a transition metal.
• External Descriptors: diamminedichloroplatinum

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in DMSO (25 mg/ml), water (0.25 g/100ml) at 25 °C, ethanol (<1 mg/ml) at 25 °C, and DMF (16 mg/ml)
• Sensitivity: Moisture sensitive & Light sensitive
• Melt Point(°C): 270°C

References

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