≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Diethyl aminomalonate hydrochloride is used as a pharmaceutical intermediate. Diethyl aminomalonate with formaldehyde generates an azomethine ylide which can undergo cycloadditions with 1,2-dipolarophiles to form pyrrolidines.
| Pubchem Sid | 504762422 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504762422 |
| Canonical Smiles | CCOC(=O)C(C(=O)OCC)N.Cl |
| IUPAC Name | diethyl 2-aminopropanedioate;hydrochloride |
| InChIKey | GLFVNTDRBTZJIY-UHFFFAOYSA-N |
| INCHI | 1S/C7H13NO4.ClH/c1-3-11-6(9)5(8)7(10)12-4-2;/h5H,3-4,8H2,1-2H3;1H |
| Isomeric SMILES | CCOC(=O)C(C(=O)OCC)N.Cl |
| WGK Germany | 3 |
| Alternate CAS | 13433-00-6,6829-40-9 (Parent),6829-40-9 |
| NSC Number | 76074 |
| MeSH Entry Terms | diethyl aminomalonate;diethyl aminomalonate hydrochloride |
| Molecular Weight | 211.64 |
| Reaxy-Rn | 3568037 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3568037&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic acids and derivatives |
| Class | Carboxylic acids and derivatives |
| Subclass | Amino acids, peptides, and analogues |
| Intermediate Tree Nodes | Amino acids and derivatives - Alpha amino acids and derivatives |
| Direct Parent | Alpha amino acid esters |
| Alternative Parents | Dicarboxylic acids and derivatives 1,3-dicarbonyl compounds Carboxylic acid esters Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aliphatic acyclic compounds |
| Substituents | Alpha-amino acid ester - Dicarboxylic acid or derivatives - 1,3-dicarbonyl compound - Carboxylic acid ester - Organic nitrogen compound - Hydrochloride - Hydrocarbon derivative - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic oxide - Organic oxygen compound - Carbonyl group - Amine - Aliphatic acyclic compound |
| Description | This compound belongs to the class of organic compounds known as alpha amino acid esters. These are ester derivatives of alpha amino acids. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 B2303329 | Certificate of Analysis | Oct 30, 2025 | D302428 |
| B2303335 | Certificate of Analysis | Oct 30, 2025 | D302428 |
| B2303336 | Certificate of Analysis | Oct 30, 2025 | D302428 |
| B2303339 | Certificate of Analysis | Oct 30, 2025 | D302428 |
| B2303340 | Certificate of Analysis | Oct 30, 2025 | D302428 |
| B2303341 | Certificate of Analysis | Oct 30, 2025 | D302428 |
| I2118305 | Certificate of Analysis | Jul 16, 2024 | D302428 |
| I2118306 | Certificate of Analysis | Jul 16, 2024 | D302428 |
| I2118307 | Certificate of Analysis | Jul 16, 2024 | D302428 |
| I2118308 | Certificate of Analysis | Jul 16, 2024 | D302428 |
| G2416221 | Certificate of Analysis | May 07, 2024 | D302428 |
| G2416571 | Certificate of Analysis | May 07, 2024 | D302428 |
| G2415610 | Certificate of Analysis | May 07, 2024 | D302428 |
| Solubility | Soluble in water |
|---|---|
| Sensitivity | Moisture sensitive |
| Melt Point(°C) | 165-170℃(dec.) (lit.) |
| Molecular Weight | 211.640 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 6 |
| Exact Mass | 211.061 Da |
| Monoisotopic Mass | 211.061 Da |
| Topological Polar Surface Area | 78.600 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 151.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
