Erythromycin lactobionate - 615u/mg , Bacterial 70S ribosome inhibitor, CAS No.3847-29-8, Bacterial 70S ribosome inhibitor

CAS: 3847-29-8 Cat. No.: E333646 Molecular Weight: 1092.22

GRADE & PURITY 615u/mg

Synonyms

DTXCID401436149 | Erythromycin mono(4-O-beta-D-galactopyranosyl-D-gluconate) (salt) | ERYTHROMYCINI LACTOBIONAS [WHO-IP LATIN] | EINECS 223-348-7 | ERYTHROMYCIN LACTOBIONATE (MART.) | Q27256272 | Metylohydrazyna | RK363YG315 | STERILE ERYTHROMYCIN LACTOBI

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Specifications

Synonyms

DTXCID401436149 | Erythromycin mono(4-O-beta-D-galactopyranosyl-D-gluconate) (salt) | ERYTHROMYCINI LACTOBIONAS [WHO-IP LATIN] | EINECS 223-348-7 | ERYTHROMYCIN LACTOBIONATE (MART.) | Q27256272 | Metylohydrazyna | RK363YG315 | STERILE ERYTHROMYCIN LACTOBI

Specifications & Purity

615u/mg

Storage

Store at 2-8°C, Desiccated

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Mechanism of action

Bacterial 70S ribosome inhibitor

Names and Identifiers

• Canonical Smiles: CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O.C(C1C(C(C(C(O1)OC(C(CO)O)C(C(C(=O)O)O)O)O)O)O)O
• IUPAC Name: (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-4-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,7,9,11,13-hexamethyl-oxacyclotetradecane-2,10-dione;(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoic acid
• InChIKey: NNRXCKZMQLFUPL-WBMZRJHASA-N
• INCHI: 1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3;3-10,12-20H,1-2H2,(H,21,22)/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-;3-,4-,5+,6+,7-,8-,9-,10-,12+/m11/s1
• Isomeric SMILES: CC[C@@H]1[C@@]([C@@H]([C@H](C(=O)[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O.C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]([C@@H](CO)O)[C@@H]([C@H](C(=O)O)O)O)O)O)O)O
• Molecular Weight: 1092.22
• Reaxy-Rn: 25684678
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25684678&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Class Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Aminosaccharides
          • Level6 Aminoglycosides

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Class: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Aminosaccharides
• Direct Parent: Aminoglycosides
• Alternative Parents: Fatty acyl glycosides of mono- and disaccharides Macrolides and analogues Disaccharides O-glycosyl compounds Medium-chain hydroxy acids and derivatives Medium-chain fatty acids Sugar acids and derivatives Beta hydroxy acids and derivatives Heterocyclic fatty acids Hydroxy fatty acids Alpha hydroxy acids and derivatives Oxanes Tertiary alcohols 1,2-aminoalcohols Trialkylamines Amino acids and derivatives Secondary alcohols Carboxylic acid esters Cyclic ketones Lactones Dialkyl ethers Acetals Polyols Oxacyclic compounds Carboxylic acids Monocarboxylic acids and derivatives Primary alcohols Hydrocarbon derivatives Organopnictogen compounds Organic oxides
• Molecular Framework: Not available
• Substituents: Aminoglycoside core - Fatty acyl glycoside of mono- or disaccharide - Fatty acyl glycoside - Macrolide - Gluconic_acid - Glycosyl compound - O-glycosyl compound - Disaccharide - Medium-chain hydroxy acid - Medium-chain fatty acid - Heterocyclic fatty acid - Sugar acid - Hydroxy fatty acid - Beta-hydroxy acid - Fatty acyl - Fatty acid - Alpha-hydroxy acid - Hydroxy acid - Oxane - Tertiary alcohol - 1,2-aminoalcohol - Amino acid or derivatives - Carboxylic acid ester - Cyclic ketone - Tertiary aliphatic amine - Tertiary amine - Secondary alcohol - Ketone - Lactone - Monocarboxylic acid or derivatives - Organoheterocyclic compound - Oxacycle - Ether - Polyol - Dialkyl ether - Carboxylic acid - Acetal - Carboxylic acid derivative - Organonitrogen compound - Carbonyl group - Organic nitrogen compound - Amine - Alcohol - Organopnictogen compound - Organic oxide - Primary alcohol - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
• Description: This compound belongs to the class of organic compounds known as aminoglycosides. These are molecules or a portion of a molecule composed of amino-modified sugars.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water, methanol, and alcohol.
• Melt Point(°C): >166° C (dec.)
• Molecular Weight: 1092.200 g/mol
• Hydrogen Bond Donor Count: 14
• Hydrogen Bond Acceptor Count: 26
• Rotatable Bond Count: 15
• Exact Mass: 1091.57 Da
• Monoisotopic Mass: 1091.57 Da
• Topological Polar Surface Area: 412.000 Ų
• Heavy Atom Count: 75
• Formal Charge: 0
• Complexity: 1580.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 27
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3