FTI-277 trifluoroacetate salt - ≥95% , CAS No.170006-73-2(free base)

CAS: 170006-73-2(free base) Cat. No.: F331609 Molecular Weight: 447.61 (free base basis)
AVAILABLE TO ORDER
GRADE & PURITY ≥95%
Storage
Store at -20°C,Argon charged
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
F331609-1mg
5
$105.90
5mg
F331609-5mg
3
$344.90
10mg
F331609-10mg
2
$529.90
25mg
F331609-25mg
2
$1,059.90
50mg
F331609-50mg
1
$1,668.90
100mg
F331609-100mg
1
$2,648.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

FTI-277 trifluoroacetate salt is an inhibitor of farnesyl transferase (FTase). Studies show the compound to be a highly potent Ras CAAX peptidomimetic which antagonizes both H- and K-Ras oncogenic signaling.

Specifications

Specifications & Purity
≥95%
Biochemical and Physiological Mechanisms
Farnesyltransferase inhibitor 277 (FTI-277) mediates apoptosis in multiple myeloma and is considered a potential therapeutic agent. Potent (pM/nM) Ras CAAX peptidomimetics that antagonize H and K-Ras oncogenic signaling. Farnesyltransferase (Ftase) inhibi
Storage
Store at -20°C, Argon charged
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
ACTIVATOR
Purity
≥95%
Names and Identifiers
Molecular Weight 447.61 (free base basis)

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

14 results found

Lot NumberCertificate TypeDateItem
E2619156Certificate of AnalysisMay 28, 2026 F331609
C2624013Certificate of AnalysisApr 03, 2026 F331609
D2308168Certificate of AnalysisJan 20, 2026 F331609
D2308177Certificate of AnalysisJan 20, 2026 F331609
D2308178Certificate of AnalysisJan 20, 2026 F331609
D2308179Certificate of AnalysisJan 20, 2026 F331609
D2308180Certificate of AnalysisJan 20, 2026 F331609
D2308181Certificate of AnalysisJan 20, 2026 F331609
D2308182Certificate of AnalysisJan 20, 2026 F331609
D2308183Certificate of AnalysisJan 20, 2026 F331609
D2308184Certificate of AnalysisJan 20, 2026 F331609
D2308185Certificate of AnalysisJan 20, 2026 F331609
D2308186Certificate of AnalysisJan 20, 2026 F331609
D2308187Certificate of AnalysisJan 20, 2026 F331609

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Chemical and Physical Properties
SolubilitySoluble in Water: ≥2 mg/mL
SensitivityAir and moisture sensitive
Citations of This Product
References
1. Sainan Zhang, Jiahui Qi, Chuanming Liu, Huidan Zhang, Bichun Guo, Die Wu, Yicen Liu, Xin Zhen, Yang Zhang, Nannan Kang, Jidong Zhou, Guijun Yan, Chaojun Li, Lijun Ding, Haixiang Sun.  (2026)  Decreased PTGES2 Farnesylation in Granulosa Cells Compromises PGE2-Dependent Cumulus Expansion and Oocyte Maturation During Ovarian Aging.  AGING CELL,  25  (2): (e70374).  [PMID:41521701] [10.1111/acel.70374]
Solution Calculators
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