Jatrorrhizine - 10mM in DMSO , CAS No.3621-38-3

CAS: 3621-38-3 Cat. No.: J423627 Molecular Weight: 355.38 EC Number: 222-817-3
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GRADE & PURITY 10mM in DMSO
Synonyms
FT-0686648 | jateorrhizine | Berbinium, 7,8,13,13a-tetradehydro-3-hydroxy-2,9,10-trimethoxy- (8CI) | Ethynyldimethylcarbinol | Trichloroethylsilicon | CHEBI:6087 | 2,2,2-Trichloro-1-ethanol | A-Tetradehydro-3-hydroxy-2,9,10-trimethoxyberbinium | NSC645313
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Status
Price
Qty
1ml
J423627-1ml
2

$132.90

$155.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 17 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
FT-0686648 | jateorrhizine | Berbinium, 7, 8, 13, 13a-tetradehydro-3-hydroxy-2, 9, 10-trimethoxy- (8CI) | Ethynyldimethylcarbinol | Trichloroethylsilicon | CHEBI:6087 | 2, 2, 2-Trichloro-1-ethanol | A-Tetradehydro-3-hydroxy-2, 9, 10-trimethoxyberbinium | NSC645313
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Novel tetrahydroisoquinoline alkaloid originally extracted from the Chinese herb Rhizoma Coptidis. Protects neuronal-like cells against H 2 O 2 -induced toxicity. Protects against okadaic acid induced oxidative toxicity through inhibiting the Mitogen-acti
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Isomeric SMILES COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC(=C(C=C4CC3)O)OC)OC
Molecular Weight 355.38
Reaxy-Rn 1555102
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1555102&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Citations of This Product
References
1. Jin Pian, Zhu Fucheng, Zhou Wen, Liu Chen, Li Na, Liu Houmei.  (2023)  Developing magnetic functionalized dendritic fibrous mesoporous silica as advanced adsorbent for quaternary ammonium alkaloids.  MICROCHIMICA ACTA,  190  (12): (1-12).  [PMID:37999777] [10.1007/s00604-023-06053-x]
2. Longlong Gao, Rui Tian, Yong Shao.  (2023)  Photocatalytic Duplex-Based DNAzymes Switched by an Abasic Site.  Chemistry-Switzerland,  (3): (1497-1507).  [PMID:] [10.3390/chemistry5030102]
3. Jiawen Han, Yaru Ding, Xujuan Lv, Yuwei Zhang, Daoqing Fan.  (2023)  Integration of G-Quadruplex and Pyrene as a Simple and Efficient Ratiometric Fluorescent Platform That Programmed by Contrary Logic Pair for Highly Sensitive and Selective Coralyne (COR) Detection.  Biosensors-Basel,  13  (4): (489).  [PMID:37185564] [10.3390/bios13040489]
4. Chao Fan, Hao Tang, Licheng Wang, Yijing Li, Xusheng Wang, Shuai Wang, Xiaojing Liang.  (2020)  The preparation of a core–shell stationary phase by the in situ polymerization of a hydrophilic polymer on the surface of silica and its chromatographic performance.  NEW JOURNAL OF CHEMISTRY,  44  (27): (11704-11709).  [PMID:] [10.1039/D0NJ01197E]
5. Weijuan Du, Lisha Jin, Liping Li, Wei Wang, Su Zeng, Huidi Jiang, Hui Zhou.  (2018)  Development and Validation of a HPLC-ESI-MS/MS Method for Simultaneous Quantification of Fourteen Alkaloids in Mouse Plasma after Oral Administration of the Extract of Corydalis yanhusuo Tuber: Application to Pharmacokinetic Study.  MOLECULES,  23  (4): (714).  [PMID:29561801] [10.3390/molecules23040714]
6. Wang Chenlu, Zhou Wei, Liao Xiaoyan, Zhang Wenpeng, Chen Zilin.  (2017)  An etched polyether ether ketone tube covered with immobilized graphene oxide for online solid phase microextraction of quaternary alkaloids prior to their quantitation by HPLC-MS/MS.  MICROCHIMICA ACTA,  184  (8): (2715-2721).  [PMID:] [10.1007/s00604-017-2262-8]
7. Yuehua Hu, Fan Lin, Tao Wu, Ying Wang, Xiao-Shun Zhou, Yong Shao.  (2016)  Fluorescently Sensing of DNA Triplex Assembly Using an Isoquinoline Alkaloid as Selector, Stabilizer, Inducer, and Switch-On Emitter.  Chemistry-An Asian Journal,  11  (14): (2041-2048).  [PMID:27252050] [10.1002/asia.201600459]
8. Zixin Zhang, Wenpeng Zhang, Tao Bao, Zilin Chen.  (2015)  Jacket-free stir bar sorptive extraction with bio-inspired polydopamine-functionalized immobilization of cross-linked polymer on stainless steel wire.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:26141275] [10.1016/j.chroma.2015.06.031]
9. Hailiang Huang, Shuo Shi, Xuyue Zheng, Tianming Yao.  (2015)  Sensitive detection for coralyne and mercury ions based on homo-A/T DNA by exonuclease signal amplification.  BIOSENSORS & BIOELECTRONICS,      [PMID:25950941] [10.1016/j.bios.2015.04.076]
10. Jiawei Meng, Wenpeng Zhang, Tao Bao, Zilin Chen.  (2015)  Novel molecularly imprinted magnetic nanoparticles for the selective extraction of protoberberine alkaloids in herbs and rat plasma.  JOURNAL OF SEPARATION SCIENCE,  38  (12): (2117-2125).  [PMID:25832420] [10.1002/jssc.201500264]
11. Zhuo Ye, Yinfeng Li, Jianguo Wen, Kunjing Li, Baoxian Ye.  (2014)  Study of the voltammetric behavior of jatrorrhizine and its sensitive determination at electrochemical pretreatment glassy carbon electrode.  TALANTA,      [PMID:24881532] [10.1016/j.talanta.2014.03.026]
12. Lihong Liu, Zilin Chen.  (2012)  Analysis of four alkaloids of Coptis chinensis in rat plasma by high performance liquid chromatography with electrochemical detection.  ANALYTICA CHIMICA ACTA,      [PMID:22769040] [10.1016/j.aca.2012.05.054]
13. Jing Zhu, Qing Hong Zhang, Wen Wu Wang.  (2024)  Pattern Recognition of Alkaloids by Inhibiting the Catalytic Activity of Dopzymes for Dopamine.  ANALYTICAL CHEMISTRY,      [PMID:39014901] [10.1021/acs.analchem.4c01920]
14. Liyun Ma, Simin Liu, Qing Wang, Lin Yao, Li Xu.  (2015)  Cucurbit(6)uril immobilized on silica: A novel high-performance liquid chromatographic stationary phase.  JOURNAL OF SEPARATION SCIENCE,  38  (7): (1082-1089).  [PMID:25641573] [10.1002/jssc.201401049]
15. Liyun Ma, Si-Min Liu, Lin Yao, Li Xu.  (2014)  Preparation and chromatographic performance evaluation of cucurbit[7]uril immobilized silica.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:25528071] [10.1016/j.chroma.2014.12.002]
16. Lilin Tang, Wenpeng Zhang, Haiyan Zhao, Zilin Chen.  (2015)  Tyrosinase inhibitor screening in traditional Chinese medicines by electrophoretically mediated microanalysis.  JOURNAL OF SEPARATION SCIENCE,  38  (16): (2887-2892).  [PMID:26037533] [10.1002/jssc.201500371]
17. Ting Liu, Jia Tang, Xinyi Lu, Lu Jiang, Rui Zhang, Miaoqing Zhang, Jingpu Zhang, Danqing Song, Dousheng Zhang, Mingzhe Xu.  (2025)  Ocular Toxicity and Mechanistic Investigation for Berberine and Its Metabolite Berberrubine on Zebrafish.  MOLECULES,  30  (23): (4602).  [PMID:41375198] [10.3390/molecules30234602]
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