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GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
Z31097998 | CCG-44815 | Oprea1_790000 | 7-chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazin-1-yl}quinoline | AS-55981 | C76482 | 7-chloro-4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)quinoline | KM11060, >=98% (HPLC) | A901612 | BCP17185 | EC-000.2090 | EN
Shipped In
Dry ice packs + Cold packs
Specifications Synonyms
Z31097998 | CCG-44815 | Oprea1_790000 | 7-chloro-4-{4-[(4-chlorophenyl)sulfonyl]piperazin-1-yl}quinoline | AS-55981 | C76482 | 7-chloro-4-(4-((4-chlorophenyl)sulfonyl)piperazin-1-yl)quinoline | KM11060, >=98% (HPLC) | A901612 | BCP17185 | EC-000.2090 | EN
Specifications & Purity
Moligand™, 10mM in DMSO
Biochemical and Physiological Mechanisms
Corrects F508del-CFTR trafficking; increases the amount of functional CFTR at the plasma membrane (~75%). Shown to inhibit PDE5 activity.
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles C1CN(CCN1C2=C3C=CC(=CC3=NC=C2)Cl)S(=O)(=O)C4=CC=C(C=C4)Cl IUPAC Name 7-chloro-4-[4-(4-chlorophenyl)sulfonylpiperazin-1-yl]quinoline InChIKey GIEHIZKCIZLXLF-UHFFFAOYSA-N INCHI 1S/C19H17Cl2N3O2S/c20-14-1-4-16(5-2-14)27(25,26)24-11-9-23(10-12-24)19-7-8-22-18-13-15(21)3-6-17(18)19/h1-8,13H,9-12H2 Isomeric SMILES C1CN(CCN1C2=C3C=CC(=CC3=NC=C2)Cl)S(=O)(=O)C4=CC=C(C=C4)Cl Alternate CAS 774549-97-2 Molecular Weight 422.33 Reaxy-Rn 15744663 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=15744663&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
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Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
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Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Diazinanes Subclass Piperazines Intermediate Tree Nodes Not available Direct Parent Pyridinylpiperazines Alternative Parents N-arylpiperazines 4-aminoquinolines Chloroquinolines Benzenesulfonamides Benzenesulfonyl compounds Dialkylarylamines Chlorobenzenes Aminopyridines and derivatives Organosulfonamides Aryl chlorides Heteroaromatic compounds Sulfonyls Azacyclic compounds Hydrocarbon derivatives Organochlorides Organopnictogen compounds Organic oxides Molecular Framework Aromatic heteropolycyclic compounds Substituents Pyridinylpiperazine - N-arylpiperazine - Aminoquinoline - 4-aminoquinoline - Haloquinoline - Chloroquinoline - Quinoline - Benzenesulfonamide - Benzenesulfonyl group - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aminopyridine - Halobenzene - Chlorobenzene - Aryl chloride - Aryl halide - Pyridine - Monocyclic benzene moiety - Benzenoid - Organosulfonic acid amide - Heteroaromatic compound - Sulfonyl - Organosulfonic acid or derivatives - Organic sulfonic acid or derivatives - Tertiary amine - Azacycle - Organonitrogen compound - Organochloride - Organohalogen compound - Amine - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organosulfur compound - Organic nitrogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as pyridinylpiperazines. These are compounds containing a pyridinylpiperazine skeleton, which consists of a pyridine linked (not fused) to a piperazine by a bond by a single bond that is not part of a ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 422.300 g/mol XLogP3 4.200 Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 3 Exact Mass 421.042 Da Monoisotopic Mass 421.042 Da Topological Polar Surface Area 61.900 Ų Heavy Atom Count 27 Formal Charge 0 Complexity 599.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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