≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Kynuramine, an endogenously occurring amine, is a fluorescent substrate and probe of plasma amine oxidase.
In Vitro
Kynuramine inhibits both presynaptic and postsynaptic α-adrenoceptors in vitro. Kynuramine has been shown to act as a partial agonist on serotonin receptors in dog cerebral arteries. Kynuramine (20 μg/mL) frequently causes a small contraction of the ileum but failed to alter the twitch response to cholinergic stimulation. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Kynuramine (0.064, 0.32, 1.6 or 8 μg; ICV; single does) may serve a physiological role in the modulation of female sexual behavior. Kynuramine (1.25, 2.5 and 5.0 mg/kg; i.v.; single does) increases heart rate and blood pressure in pithed rats. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Female rats. Dosage: 0.064-8 μg. Administration: Intraventricular administration; single does. Result: Produced facilitation of lordosis behavior. Animal Model: Male rats (about 200g). Dosage: 1.25-5.0 mg/kg. Administration: i.v.; single does. Result: Promoted heart rate and blood pressure.
Form:Solid
| Canonical Smiles | C1=CC=C(C(=C1)C(=O)CCN)N.Cl.Cl |
|---|---|
| IUPAC Name | 3-amino-1-(2-aminophenyl)propan-1-one;dihydrochloride |
| InChIKey | GIUIHRRGPBPUAO-UHFFFAOYSA-N |
| INCHI | 1S/C9H12N2O.2ClH/c10-6-5-9(12)7-3-1-2-4-8(7)11;;/h1-4H,5-6,10-11H2;2*1H |
| Isomeric SMILES | C1=CC=C(C(=C1)C(=O)CCN)N.Cl.Cl |
| Alternate CAS | 36681-58-0 |
| PubChem CID | 12954979 |
| Molecular Weight | 237.13 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organic oxygen compounds |
| Class | Organooxygen compounds |
| Subclass | Carbonyl compounds |
| Intermediate Tree Nodes | Ketones - Aryl ketones - Phenylketones |
| Direct Parent | Alkyl-phenylketones |
| Alternative Parents | Benzoyl derivatives Aryl alkyl ketones Alpha-branched alpha,beta-unsaturated ketones Vinylogous amides Enones Acryloyl compounds Organopnictogen compounds Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Alkyl-phenylketone - Aryl alkyl ketone - Benzoyl - Alpha-branched alpha,beta-unsaturated-ketone - Benzenoid - Monocyclic benzene moiety - Vinylogous amide - Alpha,beta-unsaturated ketone - Enone - Acryloyl-group - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Hydrochloride - Primary amine - Organonitrogen compound - Primary aliphatic amine - Amine - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as alkyl-phenylketones. These are aromatic compounds containing a ketone substituted by one alkyl group, and a phenyl group. |
| External Descriptors | Not available |
| Solubility | DMSO : 125 mg/mL (527.14 mM; Need ultrasonic) |
|---|---|
| Molecular Weight | 237.120 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 3 |
| Exact Mass | 236.048 Da |
| Monoisotopic Mass | 236.048 Da |
| Topological Polar Surface Area | 69.100 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 159.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 3 |
