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· · COA & SDS available for every product · Same-day shipping on in-stock items Labetalol HCl - ≥98% , Adrenergic receptor antagonist, CAS No.32780-64-6, Adrenergic receptor antagonist
Synonyms
Dibenzyl(2-chloroethyl)amine | LP00687 | MLS000069666 | NC00571 | NSC 290312 | Normodyne (TN) | [(dimethylamino)methyl]dimethylamine | 2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide;hydrochloride | 2-Hydroxy-5-(1-hydroxy-2-[(1-methyl-3-
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Room temperature Ships Normal Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Labetalol HCl is a dual antagonist for both selective alpha1-adrenergic and nonselective beta-adrenergic receptors, used in the treatment of high blood pressure.
Specifications Synonyms
Dibenzyl(2-chloroethyl)amine | LP00687 | MLS000069666 | NC00571 | NSC 290312 | Normodyne (TN) | [(dimethylamino)methyl]dimethylamine | 2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide;hydrochloride | 2-Hydroxy-5-(1-hydroxy-2-[(1-methyl-3-
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
Competitive β-adrenoceptor antagonist.
Mechanism of action
Adrenergic receptor antagonist
Names and Identifiers Pubchem Sid 488184654 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488184654 Canonical Smiles CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl IUPAC Name 2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide;hydrochloride InChIKey WQVZLXWQESQGIF-UHFFFAOYSA-N INCHI 1S/C19H24N2O3.ClH/c1-13(7-8-14-5-3-2-4-6-14)21-12-18(23)15-9-10-17(22)16(11-15)19(20)24;/h2-6,9-11,13,18,21-23H,7-8,12H2,1H3,(H2,20,24);1H Isomeric SMILES CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O.Cl WGK Germany 3 RTECS CV5376000 Molecular Weight 364.87 Reaxy-Rn 5322652 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=5322652&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Benzenoids Class Benzene and substituted derivatives Subclass Benzoic acids and derivatives Intermediate Tree Nodes Hydroxybenzoic acid derivatives - Salicylic acid and derivatives Direct Parent Salicylamides Alternative Parents Benzamides Benzoyl derivatives Aralkylamines 1-hydroxy-2-unsubstituted benzenoids Vinylogous acids Secondary alcohols Primary carboxylic acid amides Amino acids and derivatives 1,2-aminoalcohols Dialkylamines Organopnictogen compounds Organic oxides Hydrochlorides Hydrocarbon derivatives Aromatic alcohols Molecular Framework Aromatic homomonocyclic compounds Substituents Salicylamide - Benzamide - Benzoyl - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Aralkylamine - Vinylogous acid - Amino acid or derivatives - 1,2-aminoalcohol - Carboxamide group - Secondary alcohol - Primary carboxylic acid amide - Secondary amine - Carboxylic acid derivative - Secondary aliphatic amine - Organopnictogen compound - Organooxygen compound - Organonitrogen compound - Alcohol - Organic oxygen compound - Aromatic alcohol - Amine - Organic nitrogen compound - Hydrochloride - Hydrocarbon derivative - Organic oxide - Aromatic homomonocyclic compound Description This compound belongs to the class of organic compounds known as salicylamides. These are carboxamide derivatives of salicylic acid. Salicylic acid is the ortho-hydroxylated derivative of benzoic acid. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Molecular Weight 364.900 g/mol XLogP3 Hydrogen Bond Donor Count 5 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 8 Exact Mass 364.155 Da Monoisotopic Mass 364.155 Da Topological Polar Surface Area 95.600 Ų Heavy Atom Count 25 Formal Charge 0 Complexity 385.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 2 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 2
Citations of This Product References 1. Haibo You, Ben Chen, Liqun Fang, Tingting Lin, Ping Xu, Chu Chu, Shengqiang Tong. (2022) Analytical enantioseparation of N-alkyl drugs by reversed-phase liquid chromatography with carboxymethyl-β-cyclodextrin as mobile phase additive. CHIRALITY, 35 (1): (58-66). [PMID:36345792 ] [10.1002/chir.23516 ] 2. Ke Li, Xiaoyan Jia, Dawei Guo, Haiming Wang, Haonan Shui, Hongbo Qi, Hua Zhang. (2025) CGKRK-targeted lipid nanoparticles enhance in vivo rosiglitazone delivery to the placenta to ameliorate murine preeclampsia. iScience, 28 (8): (112744). [PMID:40703437 ] [10.1016/j.isci.2025.112744 ]
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