Serine/threonine-protein kinase pim-1 (PIM1)

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  1. Bisindolylmaleimide IV, Inhibitor of protein kinase C beta
    CAS: 119139-23-0 Formula: C20H13N3O2 Molecular Weight: 327.34
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(TLC)
    In Stock Item #: B166335
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    IUPAC Name
    3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione
    SMILES
    C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
    InChIKey
    DQYBRTASHMYDJG-UHFFFAOYSA-N
    InChI
    1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
    Synonyms
    CCG-206739 | HMS3229C03 | RO-316233 | Ro-31-6233 | DTXSID30152324 | FT-0694431 | GTPL5937 | HMS3401J13 | MBK3OO5K8T |...
  2. Pinocembrin
    CAS: 480-39-7 EC Number: 817-146-3 Formula: C15H12O4 Molecular Weight: 256.25
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
    In Stock Item #: P193543
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    (2S)-5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one
    SMILES
    C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=CC=C3
    InChIKey
    URFCJEUYXNAHFI-ZDUSSCGKSA-N
    InChI
    1S/C15H12O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-7,13,16-17H,8H2/t13-/m0/s1
    Synonyms
    Pinocembrin, analytical standard, 95% (TLC), solid | (2S)-5,7-dihydroxy-2-phenyl-chroman-4-one | (S)-2,3-Dihydro-5,7-...
  3. Quercetin
    CAS: 117-39-5 EC Number: 204-187-1 Formula: C15H10O7 Molecular Weight: 302.24
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥95%
    In Stock Item #: Q111274
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    IUPAC Name
    2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-one
    SMILES
    C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O
    InChIKey
    REFJWTPEDVJJIY-UHFFFAOYSA-N
    InChI
    1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
    Synonyms
    4mra | CHEBI:16243 | NCI-C60106 | QUERCETIN (USP-RS) | Quer | Spectrum3_000642 | Quercetin_sathishkumar | Korvitin | ...
  4. SGI-1776 free base, Inhibitor of fms related receptor tyrosine kinase 3;Inhibitor of histone H3 associated protein kinase;Inhibitor of Pim-1 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-2 proto-oncogene; serine/threonine kinase;Inhibitor of Pim-3 proto-oncogene;
    CAS: 1025065-69-3 PubChem CID: 24795070 Formula: C20H22F3N5O Molecular Weight: 405.42
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: S126376
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    IUPAC Name
    N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[1,2-b]pyridazin-6-amine
    SMILES
    CN1CCC(CC1)CNC2=NN3C(=NC=C3C4=CC(=CC=C4)OC(F)(F)F)C=C2
    InChIKey
    MHXGEROHKGDZGO-UHFFFAOYSA-N
    InChI
    1S/C20H22F3N5O/c1-27-9-7-14(8-10-27)12-24-18-5-6-19-25-13-17(28(19)26-18)15-3-2-4-16(11-15)29-20(21,22)23/h2-6,11,13-14H,7-10,12H2,1H3,(H,24,26)
    Synonyms
    N-[(1-methylpiperidin-4-yl)methyl]-3-[3-(trifluoromethoxy)phenyl]imidazo[2,1-f]pyridazin-6-amine | Imidazo[1,2-b]pyri...
  5. SMI-4a
    CAS: 438190-29-5 EC Number: 803-742-0 PubChem CID: 1361334 Formula: C11H6F3NO2S Molecular Weight: 273.23
    In Stock Item #: T125988
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    IUPAC Name
    (5Z)-5-[[3-(trifluoromethyl)phenyl]methylidene]-1,3-thiazolidine-2,4-dione
    SMILES
    C1=CC(=CC(=C1)C(F)(F)F)C=C2C(=O)NC(=O)S2
    InChIKey
    NGJLOFCOEOHFKQ-YVMONPNESA-N
    InChI
    1S/C11H6F3NO2S/c12-11(13,14)7-3-1-2-6(4-7)5-8-9(16)15-10(17)18-8/h1-5H,(H,15,16,17)/b8-5-
    Synonyms
    5-(3-(Trifluoromethyl)benzylidene)thiazolidine-2,4-dione | 5-[[3-(trifluoromethyl)phenyl]methylene]-2,4-thiazolidined...
  6. 6-Bromo-4-hydroxyquinazoline
    CAS: 32084-59-6 EC Number: 696-207-4 Formula: C8H5BrN2O Molecular Weight: 225.05
    In Stock Item #: B152546
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    IUPAC Name
    6-bromo-3H-quinazolin-4-one
    SMILES
    C1=CC2=C(C=C1Br)C(=O)NC=N2
    InChIKey
    OVEISJPVPHWEHR-UHFFFAOYSA-N
    InChI
    1S/C8H5BrN2O/c9-5-1-2-7-6(3-5)8(12)11-4-10-7/h1-4H,(H,10,11,12)
    Synonyms
    STL169355 | HMS1583H20 | 6-bromoquinazolin-4(3H)-one | MFCD00115131 | SCHEMBL182871 | STL511999 | 6-bromo-4-quinazoli...
  7. Benzofuran-2-carboxylic acid
    CAS: 496-41-3 EC Number: 207-818-9 Formula: C9H6O3 Molecular Weight: 162.14
    In Stock Item #: B170589
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    IUPAC Name
    1-benzofuran-2-carboxylic acid
    SMILES
    C1=CC=C2C(=C1)C=C(O2)C(=O)O
    InChIKey
    OFFSPAZVIVZPHU-UHFFFAOYSA-N
    InChI
    1S/C9H6O3/c10-9(11)8-5-6-3-1-2-4-7(6)12-8/h1-5H,(H,10,11)
    Synonyms
    AB01319519-02 | AI3-03711 | SY005603 | NSC6165 | NSC-6165 | Benzo[b]furan-2-carboxylic acid | O11693 | 2-BENZOFURANCA...
  8. 6-Bromo-4-hydroxycoumarin
    CAS: 4139-61-1 EC Number: 672-569-9 Formula: C9H5BrO3 Molecular Weight: 241.04
    In Stock Item #: B170240
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    IUPAC Name
    6-bromo-4-hydroxychromen-2-one
    SMILES
    C1=CC2=C(C=C1Br)C(=CC(=O)O2)O
    InChIKey
    KNMCTCABMSGXGR-UHFFFAOYSA-N
    InChI
    1S/C9H5BrO3/c10-5-1-2-8-6(3-5)7(11)4-9(12)13-8/h1-4,11H
    Synonyms
    2H-1-Benzopyran-2-one, 6-bromo-4-hydroxy- | KNMCTCABMSGXGR-UHFFFAOYSA-N | Q27451062 | 4-hydroxy-6-bromocoumarin | SCH...
  9. Hispidulin
    CAS: 1447-88-7 EC Number: 802-856-8 Formula: C16H12O6 Molecular Weight: 300.26
    In Stock Item #: H167320
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    IUPAC Name
    5,7-dihydroxy-2-(4-hydroxyphenyl)-6-methoxychromen-4-one
    SMILES
    COC1=C(C2=C(C=C1O)OC(=CC2=O)C3=CC=C(C=C3)O)O
    InChIKey
    IHFBPDAQLQOCBX-UHFFFAOYSA-N
    InChI
    1S/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3
    Synonyms
    methoxyapigenin | SMR000445653 | BRD-K72066874-001-01-0 | TCMDC-123942 | Flavone,5,7-trihydroxy-6-methoxy- | UNII-N7F...
  10. A 484954
    CAS: 142557-61-7 EC Number: 802-826-4 Formula: C13H15N5O3 Molecular Weight: 289.29
    In Stock Item #: A288912
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    IUPAC Name
    7-amino-1-cyclopropyl-3-ethyl-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide
    SMILES
    CCN1C(=O)C2=CC(=C(N=C2N(C1=O)C3CC3)N)C(=O)N
    InChIKey
    HWODCHXORCTEGU-UHFFFAOYSA-N
    InChI
    1S/C13H15N5O3/c1-2-17-12(20)8-5-7(10(15)19)9(14)16-11(8)18(13(17)21)6-3-4-6/h5-6H,2-4H2,1H3,(H2,14,16)(H2,15,19)
    Synonyms
    7-amino-1-cyclopropyl-3-ethyl-2,4-dioxo-1,2,3,4-tetrahydropyrido[2,3-d]pyrimidine-6-carboxamide | A 484954 | HY-11009...
  11. 9H-Pyrido[3,4-b]indole, Inhibitor of indoleamine 2;3-dioxygenase 1
    CAS: 244-63-3 EC Number: 205-959-0 Formula: C11H8N2 Molecular Weight: 168.2
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: N132898
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    IUPAC Name
    9H-pyrido[3,4-b]indole
    SMILES
    C1=CC=C2C(=C1)C3=C(N2)C=NC=C3
    InChIKey
    AIFRHYZBTHREPW-UHFFFAOYSA-N
    InChI
    1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H
    Synonyms
    Carbazoline | KBioGR_002537 | P1121 | NCGC00018245-04 | NCGC00021302-03 | Norharman - free base | Norharmane, 98% | S...
  12. Myricetin
    CAS: 529-44-2 EC Number: 208-463-2 Formula: C15H10O8 Molecular Weight: 318.24
    Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods. ≥98%
    In Stock Item #: M111176
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    IUPAC Name
    3,5,7-trihydroxy-2-(3,4,5-trihydroxyphenyl)chromen-4-one
    SMILES
    C1=C(C=C(C(=C1O)O)O)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
    InChIKey
    IKMDFBPHZNJCSN-UHFFFAOYSA-N
    InChI
    1S/C15H10O8/c16-6-3-7(17)11-10(4-6)23-15(14(22)13(11)21)5-1-8(18)12(20)9(19)2-5/h1-4,16-20,22H
    Synonyms
    BIDD:PXR0079 | NCGC00015697-01 | NCGC00179517-01 | FLAVONE, 3,3',4',5,5',7-HEXAHYDROXY- | NCGC00015697-07 | Myricetin...
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