Minaprine dihydrochloride - Moligand™, ≥99% , Serotonin 2 (5-HT2) receptor, CAS No.25953-17-7, Serotonin 2 (5-HT2) receptor

CAS: 25953-17-7 Cat. No.: M651514 Molecular Weight: 371.3 PubChem CID: 33254
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
Synonyms
MS-25973 | SPECTRUM1501120 | Prestwick_2 | 4-MORPHOLINEETHANAMINE, N-(4-METHYL-6-PHENYL-3-PYRIDAZINYL)-, DIHYDROCHLORIDE (2) 4-(2-((4-METHYL-6-PHENYL-3-PYRIDAZINYL)AMINO)ETHYL)MORPHOLINE DIHYDROCHLORIDE. | MINAPRINE HYDROCHLORIDE [MART.] | Q27122287 | MIN
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
25mg
M651514-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

$31.90

$47.90
Save $16.00 (33.40%)
100mg
M651514-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

$100.90

$151.90
Save $51.00 (33.57%)
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Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Minaprine dihydrochloride is a reversible inhibitor of MAO-A ; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression.

Form:Solid

Specifications

Synonyms
MS-25973 | SPECTRUM1501120 | Prestwick_2 | 4-MORPHOLINEETHANAMINE, N-(4-METHYL-6-PHENYL-3-PYRIDAZINYL)-, DIHYDROCHLORIDE (2) 4-(2-((4-METHYL-6-PHENYL-3-PYRIDAZINYL)AMINO)ETHYL)MORPHOLINE DIHYDROCHLORIDE. | MINAPRINE HYDROCHLORIDE [MART.] | Q27122287 | MIN
Specifications & Purity
Moligand™, ≥99%
Biochemical and Physiological Mechanisms
Minaprine dihydrochloride is a reversible inhibitor of MAO-A ; weakly inhibit acetylcholinesterase; an antidepressant for treatment of depression.
Storage
Store at 2-8°C, Desiccated
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Mechanism of action
Serotonin 2 (5-HT2) receptor
Purity
≥99%
Names and Identifiers
Canonical SmilesCC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3.Cl.Cl
IUPAC Name4-methyl-N-(2-morpholin-4-ylethyl)-6-phenylpyridazin-3-amine;dihydrochloride
InChIKeyGNUCGROXDZMCJI-UHFFFAOYSA-N
INCHI1S/C17H22N4O.2ClH/c1-14-13-16(15-5-3-2-4-6-15)19-20-17(14)18-7-8-21-9-11-22-12-10-21;;/h2-6,13H,7-12H2,1H3,(H,18,20);2*1H
Isomeric SMILES CC1=CC(=NN=C1NCCN2CCOCC2)C3=CC=CC=C3.Cl.Cl
Alternate CAS 25953-17-7,25905-77-5 (Parent)
PubChem CID 33254
MeSH Entry Terms 3-(2-morpholino-ethylamino)-4-methyl-6-phenyl pyridazine, dihydrochloride;3-(morpholinoethyl)amino-4-methyl-6-phenylpyridazine;Agr 1240;Cantor;minaprine;minaprine dihydrochloride;MINAPRINE HYDROCHLORIDE
Molecular Weight 371.3

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

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Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassDiazines
SubclassPyridazines and derivatives
Intermediate Tree Nodes Not available
Direct ParentPhenylpyridazines
Alternative Parents Morpholines  Imidolactams  Benzene and substituted derivatives  Heteroaromatic compounds  Trialkylamines  Oxacyclic compounds  Dialkyl ethers  Azacyclic compounds  Organopnictogen compounds  Hydrochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Phenylpyridazine - Monocyclic benzene moiety - Morpholine - Oxazinane - Benzenoid - Imidolactam - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Oxacycle - Azacycle - Ether - Dialkyl ether - Hydrochloride - Amine - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phenylpyridazines. These are organic compounds containing a pyridazine ring substituted by a phenyl group.
External Descriptors hydrochloride
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Chemical and Physical Properties
SolubilityDMSO : ≥ 100 mg/mL (269.32 mM) H2O : 100 mg/mL (269.32 mM; Need ultrasonic)
SensitivityMoisture sensitive
Molecular Weight371.300 g/mol
XLogP3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count5
Exact Mass370.133 Da
Monoisotopic Mass370.133 Da
Topological Polar Surface Area50.300 Ų
Heavy Atom Count24
Formal Charge0
Complexity316.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count3
Solution Calculators
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