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Mosloflavone - Moligand™, ≥99% , CAS No.740-33-0

CAS: 740-33-0 Cat. No.: M647485 Molecular Weight: 298.29 PubChem CID: 471722
COA
Mosloflavone - Moligand™, ≥99% CAS No(740-33-0) by Aladdin Scientific
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
Synonyms
DTXSID00224789 | AC-34609 | BAICALEIN-6,7-DIMETHYL ETHER | SCHEMBL971985 | ESTRA-1,3,5(10)-TRIENE-3,17-DIOL, 16-(FLUORO-18F)-, (16alpha,17beta)- | SIVAITYPYQQYAP-UHFFFAOYSA-N | FT-0663427 | Mosloflavone | 4H-1-Benzopyran-4-one, 5-hydroxy-6,7-dimethoxy-2-p
Storage
Protected from light,Store at -20°C
Shipped In
Ice chest + Ice pads
★
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
1mg
M647485-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$9.90
5mg
M647485-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$29.90
25mg
M647485-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$90.90
100mg
M647485-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$219.90
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Overview Specifications Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews
🧪

Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with  anti-EV71 activity. Mosloflavone  inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein synthesis. Mosloflavone is a promising biocide and inhibits P. aeruginosa virulence and biofilm formation.

In Vitro

Mosloflavone shows promising anti-inflammatory activity via inhibition of TNF-α and IL-1β with IC 50 values of 16.4 uM and 6.4 uM, respectively; inhibits TNF-α, IL-1β and iNOS levels in the supernatant of mouse macrophage cell line J774A as a dose-dependent manner, it also can be used as a starting point to discover lead structures for treatment of inflammatory and immunomodulatory diseases. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:IC50: EV71,bacterial

Specifications

Synonyms
DTXSID00224789 | AC-34609 | BAICALEIN-6, 7-DIMETHYL ETHER | SCHEMBL971985 | ESTRA-1, 3, 5(10)-TRIENE-3, 17-DIOL, 16-(FLUORO-18F)-, (16alpha, 17beta)- | SIVAITYPYQQYAP-UHFFFAOYSA-N | FT-0663427 | Mosloflavone | 4H-1-Benzopyran-4-one, 5-hydroxy-6, 7-dimethoxy-2-p
Specifications & Purity
Moligand™, ≥99%
Biochemical and Physiological Mechanisms
Mosloflavone is a flavonoid isolated from Scutellaria baicalensis Georgi with xa0anti-EV71 activity. Mosloflavonexa0 inhibits VP2 virus replication and protein expression during the initial stage of virus infection and inhibits viral VP2 capsid protein s
Storage
Protected from light, Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Grade
Moligand™
Action Type
INHIBITOR
Purity
≥99%
Names and Identifiers
Canonical SmilesCOC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)OC
IUPAC Name5-hydroxy-6,7-dimethoxy-2-phenylchromen-4-one
InChIKeySIVAITYPYQQYAP-UHFFFAOYSA-N
INCHI1S/C17H14O5/c1-20-14-9-13-15(16(19)17(14)21-2)11(18)8-12(22-13)10-6-4-3-5-7-10/h3-9,19H,1-2H3
Isomeric SMILES COC1=C(C(=C2C(=C1)OC(=CC2=O)C3=CC=CC=C3)O)OC
PubChem CID 471722
Molecular Weight 298.29

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassPhenylpropanoids and polyketides
ClassFlavonoids
SubclassO-methylated flavonoids
Intermediate Tree Nodes Not available
Direct Parent7-O-methylated flavonoids
Alternative Parents 6-O-methylated flavonoids  Flavones  5-hydroxyflavonoids  Chromones  Anisoles  Pyranones and derivatives  Alkyl aryl ethers  1-hydroxy-4-unsubstituted benzenoids  Benzene and substituted derivatives  Vinylogous acids  Heteroaromatic compounds  Oxacyclic compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents 6-methoxyflavonoid-skeleton - 7-methoxyflavonoid-skeleton - 5-hydroxyflavonoid - Flavone - Hydroxyflavonoid - Chromone - Benzopyran - 1-benzopyran - Anisole - 1-hydroxy-4-unsubstituted benzenoid - Alkyl aryl ether - Pyranone - Benzenoid - Pyran - Monocyclic benzene moiety - Vinylogous acid - Heteroaromatic compound - Oxacycle - Organoheterocyclic compound - Ether - Organic oxide - Organic oxygen compound - Organooxygen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as 7-o-methylated flavonoids. These are flavonoids with methoxy groups attached to the C7 atom of the flavonoid backbone.
External Descriptors Flavones and Flavonols
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
KB 3-1 (1143 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MCF7 (126967 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
H9 (1832 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
NCI-H460 (60772 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SF-268 (49410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KB (17409 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella aerogenes (4963 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus sp. (164 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HT-22 (3261 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Avian myoblastosis virus polyprotein II (68 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
K2525706Certificate of AnalysisSep 30, 2025 M647485
K2525707Certificate of AnalysisSep 30, 2025 M647485
K2525720Certificate of AnalysisSep 30, 2025 M647485
K2525725Certificate of AnalysisSep 30, 2025 M647485
Chemical and Physical Properties
SolubilityDMSO : 50 mg/mL (167.62 mM; Need ultrasonic)
SensitivityLight sensitive
Flash Point(°F)Not applicable
Flash Point(°C)Not applicable
Molecular Weight298.290 g/mol
XLogP33.300
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass298.084 Da
Monoisotopic Mass298.084 Da
Topological Polar Surface Area65.000 Ų
Heavy Atom Count22
Formal Charge0
Complexity440.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Solution Calculators
Reviews

Customer Reviews

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