N6,2′-O-Dimethyladenosine - ≥99% , CAS No.57817-83-1

CAS: 57817-83-1 Cat. No.: N650721 Molecular Weight: 295.29 PubChem CID: 6453528

GRADE & PURITY ≥99%

Synonyms

AKOS005257117 | N6,2 inverted exclamation marka-O-Dimethyladenosine | Sulodexido | 75HGV0062C | (2R,3R,4R,5R)-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)-9H-purin-9-yl]oxolan-3-ol | Glucorono-2-amino-2-deoxyglucoglucan sulfate | Glucuronylglucosaminegl

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

N6,2′-O-Dimethyladenosine, a substrate of fat mass and obesity-associated gene (FTO), is a reversible modification widely occurred on varied RNA molecules. N6,2′-O-Dimethyladenosine can regulate obesity.

Form:Solid

Specifications

Synonyms

AKOS005257117 | N6, 2 inverted exclamation marka-O-Dimethyladenosine | Sulodexido | 75HGV0062C | (2R, 3R, 4R, 5R)-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)-9H-purin-9-yl]oxolan-3-ol | Glucorono-2-amino-2-deoxyglucoglucan sulfate | Glucuronylglucosaminegl

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

N6, 2′-O-Dimethyladenosine, a substrate of fat mass and obesity-associated gene (FTO), is a reversible modification widely occurred on varied RNA molecules. N6, 2′-O-Dimethyladenosine can regulate obesity.

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥99%

Names and Identifiers

• Canonical Smiles: CNC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)OC
• IUPAC Name: (2R,3R,4R,5R)-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol
• InChIKey: GRYSXUXXBDSYRT-WOUKDFQISA-N
• INCHI: 1S/C12H17N5O4/c1-13-10-7-11(15-4-14-10)17(5-16-7)12-9(20-2)8(19)6(3-18)21-12/h4-6,8-9,12,18-19H,3H2,1-2H3,(H,13,14,15)/t6-,8-,9-,12-/m1/s1
• Isomeric SMILES: CNC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)OC
• Alternate CAS: 57817-83-1,57821-29-1
• PubChem CID: 6453528
• MeSH Entry Terms: N(6),O(2)-dimethyladenosine
• Molecular Weight: 295.29

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class Purine nucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: Purine nucleosides
• Subclass: Not available
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine nucleosides
• Alternative Parents: 6-alkylaminopurines Glycosylamines Secondary alkylarylamines Aminopyrimidines and derivatives Imidolactams Monosaccharides N-substituted imidazoles Tetrahydrofurans Heteroaromatic compounds Secondary alcohols Dialkyl ethers Azacyclic compounds Oxacyclic compounds Hydrocarbon derivatives Primary alcohols Organopnictogen compounds
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine nucleoside - Glycosyl compound - N-glycosyl compound - 6-alkylaminopurine - 6-aminopurine - Imidazopyrimidine - Purine - Aminopyrimidine - Secondary aliphatic/aromatic amine - Imidolactam - Pyrimidine - Monosaccharide - N-substituted imidazole - Heteroaromatic compound - Azole - Imidazole - Tetrahydrofuran - Secondary alcohol - Oxacycle - Azacycle - Dialkyl ether - Ether - Organoheterocyclic compound - Secondary amine - Alcohol - Organic oxygen compound - Hydrocarbon derivative - Amine - Organopnictogen compound - Organic nitrogen compound - Primary alcohol - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as purine nucleosides. These are compounds comprising a purine base attached to a ribosyl or deoxyribosyl moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: DMSO : 250 mg/mL (846.63 mM; Need ultrasonic)
• Molecular Weight: 295.290 g/mol
• XLogP3: 0.200
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 4
• Exact Mass: 295.128 Da
• Monoisotopic Mass: 295.128 Da
• Topological Polar Surface Area: 115.000 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 363.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1