Origanum oil , CAS No.8007-11-2

CAS: 8007-11-2 Cat. No.: O137777 EC Number: 616-905-4

Synonyms

Oil of Origanum

Storage

Protected from light,Room temperature

Shipped In

Normal

Overview

Oregano oil (CAS 8007‑11‑2) is a natural volatile oil extracted from oregano of the Lamiaceae family, and is a feed medicinal additive approved by the Ministry of Agriculture of China. Its main active ingredients are carvacrol (approximately 60%) and thymol (about 8%). It is a pale yellow to brown‑red oily liquid with a pungent odor, insoluble in water but soluble in ethanol and non‑volatile oils, with a boiling point of 236–237 °C and a density of approximately 0.939. Oregano oil exerts broad‑spectrum antibacterial effects by penetrating the cell membranes of pathogens and disrupting their water balance. Its active components function by damaging pathogenic bacterial cell membranes and inhibiting protein synthesis and DNA replication. It shows remarkable inhibitory effects against livestock and poultry pathogenic bacteria such as Escherichia coli and Salmonella, and can improve meat quality and feed utilization efficiency. Studies have confirmed that carvacrol, its principal active ingredient, also inhibits phytopathogenic fungi including Sclerotium rolfsii. Besides being used as a feed additive, oregano oil can also be applied to egg preservation and pharmaceutical fields. In 2024, the European Food Safety Authority (EFSA) assessed that Spanish oregano oil is safe as a sensory additive for all animal species under recommended conditions of use, and proposed the maximum dosage in compound feeds. In 2026, the European Commission issued a regulation refusing the approval of carvacrol preparations as feed additives for weaned piglets. As a feed additive, its premix form can be used synergistically with other feed ingredients for the prevention and treatment of digestive tract diseases in livestock and poultry.

Specifications

Synonyms

Oil of Origanum

Storage

Protected from light, Room temperature

Shipped In

Normal

Names and Identifiers

• WGK Germany: 3
• RTECS: RM2660000
• UN Number: 2810

Chemical and Physical Properties

• Sensitivity: Light Sensitive
• Refractive Index: 1.508
• Flash Point(°F): 145.4℉
• Flash Point(°C): 63 °C
• Boil Point(°C): 239°C

References

1. Cheng Zhang, Weihao Li, Ligong Chen, Zhaoliang Chen, Xuejing Wang, Qianqian Xu, Hailong Zhang, Huan Chen, Juxiang Liu.  (2022)  Oregano Oil Combined with Macleaya Cordata Oral Solution Improves the Growth Performance and Immune Response of Broilers.  Animals,  12  (18): (2480).  [PMID:36139338] [10.3390/ani12182480]

2. Huimin Chen, Jing Cheng, Xixi Cai, Jinzhi Han, Xu Chen, Lijun You, Caihua Xiong, Shaoyun Wang.  (2022)  pH-Switchable Antimicrobial Supramolecular Hydrogels for Synergistically Eliminating Biofilm and Promoting Wound Healing.  ACS Applied Materials & Interfaces,      [PMID:35394280] [10.1021/acsami.2c00580]

3. Yu Duan, Dexiang Wang, Shengnan Li, Minkang Hu, Boyang Qin, Yu Lv, Haijun Du, Jun Feng.  (2024)  A novel electrochemical sensor based on Pb0.95Ti0.05O-decorated nitrogen self-doped biochar for highly sensitive and selective detection of carvacrol.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2024.111019]

4. Peng Guo, Zhenye Li, Ting Cai, Du Guo, Baowei Yang, Chunling Zhang, Zhongguo Shan, Xin Wang, Xiaoli Peng, Guorong Liu, Chao Shi, Metab Alharbi, Abdullah F Alasmari.  (2024)  Inhibitory effect and mechanism of oregano essential oil on Listeria monocytogenes cells, toxins and biofilms.  MICROBIAL PATHOGENESIS,      [PMID:39025378] [10.1016/j.micpath.2024.106801]

5. Si Shi, Junjie Tang, Yanyan Zhou, Hongyan Huang, Jianxi Zhang, Wenhao Liu, Zhiwen Hu, Hongwei Wang, Jie Pang, Chunhua Wu.  (2025)  Development of sodium alginate-based active packaging films reinforced with curcumin/β-cyclodextrin stabilized high internal phase Pickering emulsions for blueberry preservation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40738430] [10.1016/j.ijbiomac.2025.146365]

6. Yuhang Cao, Lingyu Yin, Fei Li, Yi Deng, Baohua Kong, Qian Liu, Hao Wang, Hui Wang.  (2024)  Characterization of sodium alginate film containing zein-Arabic gum nanoparticles encapsulated with oregano essential oil for chilled pork packaging.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39154685] [10.1016/j.ijbiomac.2024.134824]

7. Lingyu Yin, Yuhang Cao, Meihui Wang, Baohua Kong, Qian Liu, Hui Wang, Hao Wang.  (2024)  Zein-quercetin covalent nanoparticles encapsulating oregano essential oil: Improved stability, antioxidant, and antibacterial properties.  PROCESS BIOCHEMISTRY,      [PMID:] [10.1016/j.procbio.2024.12.015]

8. Qiaoqiao Liu, Yangcheng Xu, Hang Su, Zheliang Nie, Xin Shi, Bingcheng Ge, Shuyan Gao.  (2025)  Eco-friendly antioxidant carboxymethyl cellulose /pectin films incorporating oregano essential oil and vanillic acid for tomato shelf-life extension.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:40885349] [10.1016/j.ijbiomac.2025.147151]

9. Yi Lu, Zhenyue Li, Zitong Yang, Ran Zhu, Mengxi Yan, Zhuhua Liu, Mingli Liu, Yuan Wang, Jue Wang, Qi Wang, Juxiang Liu, Cheng Zhang, Xuejing Wang, Huan Cui.  (2025)  Effects of Combined Oregano Essential Oil and Macleaya cordata Extract on Growth, Antioxidant Capacity, Immune Function, and Fecal Microbiota in Broilers.  Veterinary Sciences,  12  (12): (1206).  [PMID:41472186] [10.3390/vetsci12121206]