Rosiglitazone HCl - ≥99% , CAS No.302543-62-0

CAS: 302543-62-0 Cat. No.: R129769 Molecular Weight: 393.89 PubChem CID: 9865387
AVAILABLE TO ORDER
GRADE & PURITY ≥99%
Synonyms
5-[[4-[2-[methyl(2-pyridinyl)amino]ethoxy]phenyl]methyl]thiazolidine-2,4-dione hydrochloride | SCHEMBL3375739 | Q27288508 | 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)-thiazolidine-2,4-dione hydrochloride | 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
R129769-5mg
2
$15.90
25mg
R129769-25mg
3
$32.90
100mg
R129769-100mg
3
$36.90
250mg
R129769-250mg
3
$55.90
1g
R129769-1g
1
$73.90
5g
R129769-5g
1
$170.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
5-[[4-[2-[methyl(2-pyridinyl)amino]ethoxy]phenyl]methyl]thiazolidine-2, 4-dione hydrochloride | SCHEMBL3375739 | Q27288508 | 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)benzyl)-thiazolidine-2, 4-dione hydrochloride | 5-(4-(2-(Methyl(pyridin-2-yl)amino)ethoxy)
Specifications & Purity
≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥99%
Names and Identifiers
Pubchem Sid504765007
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504765007
Canonical SmilesCN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.Cl
IUPAC Name5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione;hydrochloride
InChIKeyXRSCTTPDKURIIJ-UHFFFAOYSA-N
INCHI1S/C18H19N3O3S.ClH/c1-21(16-4-2-3-9-19-16)10-11-24-14-7-5-13(6-8-14)12-15-17(22)20-18(23)25-15;/h2-9,15H,10-12H2,1H3,(H,20,22,23);1H
Isomeric SMILES CN(CCOC1=CC=C(C=C1)CC2C(=O)NC(=O)S2)C3=CC=CC=N3.Cl
PubChem CID 9865387
Molecular Weight 393.89

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClassPhenol ethers
SubclassNot available
Intermediate Tree Nodes Not available
Direct ParentPhenol ethers
Alternative Parents Phenoxy compounds  Dialkylarylamines  Thiazolidinediones  Alkyl aryl ethers  Aminopyridines and derivatives  Imidolactams  Heteroaromatic compounds  Dicarboximides  Thiocarbamic acid derivatives  Organic carbonic acids and derivatives  Azacyclic compounds  Hydrocarbon derivatives  Carbonyl compounds  Hydrochlorides  Organic oxides  Organopnictogen compounds  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Phenoxy compound - Phenol ether - Dialkylarylamine - Alkyl aryl ether - Aminopyridine - Thiazolidinedione - Monocyclic benzene moiety - Pyridine - Imidolactam - Dicarboximide - Heteroaromatic compound - Thiazolidine - Thiocarbamic acid derivative - Carbonic acid derivative - Ether - Carboxylic acid derivative - Azacycle - Organoheterocyclic compound - Organic oxygen compound - Hydrocarbon derivative - Organic oxide - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Carbonyl group - Organopnictogen compound - Hydrochloride - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phenol ethers. These are aromatic compounds containing an ether group substituted with a benzene ring.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
RAPGEF3 Tchem Rap guanine nucleotide exchange factor 3 (15528 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KEAP1 Tclin Kelch-like ECH-associated protein 1 (1736 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Nfe2l2 Nuclear factor erythroid 2-related factor 2 (214 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

16 results found

Lot NumberCertificate TypeDateItem
G2419457Certificate of AnalysisMay 09, 2026 R129769
G2419458Certificate of AnalysisMay 09, 2026 R129769
G2419468Certificate of AnalysisMay 09, 2026 R129769
G2419469Certificate of AnalysisMay 09, 2026 R129769
G2408458Certificate of AnalysisApr 07, 2026 R129769
G2408459Certificate of AnalysisApr 07, 2026 R129769
G2408460Certificate of AnalysisApr 07, 2026 R129769
G2408464Certificate of AnalysisApr 07, 2026 R129769
G2408465Certificate of AnalysisApr 07, 2026 R129769
G2408466Certificate of AnalysisApr 07, 2026 R129769
G2408469Certificate of AnalysisApr 07, 2026 R129769
G2408471Certificate of AnalysisApr 07, 2026 R129769
G2408473Certificate of AnalysisApr 07, 2026 R129769
G2419474Certificate of AnalysisJul 26, 2024 R129769
E2305064Certificate of AnalysisJan 06, 2023 R129769
F1501139Certificate of AnalysisJan 06, 2023 R129769

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Chemical and Physical Properties
SolubilityDMSO 79 mg/mL Water <1 mg/mL Ethanol 79 mg/mL
Molecular Weight393.900 g/mol
XLogP3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass393.091 Da
Monoisotopic Mass393.091 Da
Topological Polar Surface Area96.800 Ų
Heavy Atom Count26
Formal Charge0
Complexity468.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Citations of This Product
References
1. Li Tao, Yu-Feng Xue, Fei-Fei Sun, Xue He, Hong-Qian Wang, Cheng-Cheng Tong, Cheng Zhang, De-Xiang Xu, Xi Chen.  (2024)  MitoQ protects against carbon tetrachloride-induced hepatocyte ferroptosis and acute liver injury by suppressing mtROS-mediated ACSL4 upregulation.  TOXICOLOGY AND APPLIED PHARMACOLOGY,      [PMID:38522585] [10.1016/j.taap.2024.116914]
Solution Calculators
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