Seco Rapamycin ethyl ester - ≥85% , CAS No.S659102

CAS: S659102 Cat. No.: S659102 Molecular Weight: 942.23

GRADE & PURITY ≥85%

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Overview

Seco Rapamycin ethyl ester is an open-ring metabolite of Rapamycin derivative. Seco-rapamycin is reported not to affect the mTOR function.

Appearance:Oil

In Vitro:Disposition of Seco Rapamycin in Human Tissue Homogenates and Caco-2 Cell Monolayers. To determine whether Seco Rapamycin (D2) can be metabolized to dihydro Sirolimus (M2), 20μM Seco Rapamycin is incubated with human liver, jejunal mucosal, and Caco-2 hom

Biological Activity:Seco Rapamycin ethyl ester is an open-ring metabolite of Rapamycin derivative. Seco-rapamycin is reported not to affect the mTOR function.

Specifications

Specifications & Purity

≥85%

Storage

Protected from light, Store at -20°C, Argon charged

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥85%

Names and Identifiers

• Canonical Smiles: C[C@H]1[C@@](C(C(N2[C@H](C(OCC)=O)CCCC2)=O)=O)(O)O[C@H](C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C([C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(/C=C/[C@H](C)C[C@@H]3CC[C@@H](O)[C@H](OC)C3)=O)=O)CC1
• Molecular Weight: 942.23

Chemical and Physical Properties

• Solubility: DMSO : 100 mg/mL (106.13 mM; Need ultrasonic)