sn-Glycerol 3-phosphate lithium salt - Moligand™, ≥95% , CAS No.17989-41-2

CAS: 17989-41-2 Cat. No.: G696252 Molecular Weight: 183.94

GRADE & PURITY Moligand™, ≥95%

Synonyms

Glycerol 3-phosphate | sn-Glycerol 3-phosphate

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Overview

sn-Glycerol 3-phosphate is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate for lipid metabolism .

Specifications

Synonyms

Glycerol 3-phosphate | sn-Glycerol 3-phosphate

Specifications & Purity

Moligand™, ≥95%

Biochemical and Physiological Mechanisms

Glycerol 3-phosphate (G3P) is an important intermediate of carbohydrate and lipid metabolic pathways. It is produced from glycerol by glycerol kinase or from dihydroxyacetone phosphate by glycerol 3-phosphate dehydrogenase. G3P may enter the G3P shuttle t

Storage

Store at 2-8°C, Argon charged

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥95%

Product Properties

• ALogP: -2.9

Names and Identifiers

• Canonical Smiles: C(C(COP(=O)(O)O)O)O
• IUPAC Name: [(2R)-2,3-dihydroxypropyl] dihydrogen phosphate
• InChIKey: AWUCVROLDVIAJX-GSVOUGTGSA-N
• INCHI: 1S/C3H9O6P/c4-1-3(5)2-9-10(6,7)8/h3-5H,1-2H2,(H2,6,7,8)/t3-/m1/s1
• Isomeric SMILES: C([C@H](COP(=O)(O)O)O)O
• Molecular Weight: 183.94
• Reaxy-Rn: 1723974
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1723974&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Class Glycerophospholipids
      • Subclass Glycerophosphates

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Class: Glycerophospholipids
• Subclass: Glycerophosphates
• Intermediate Tree Nodes: Not available
• Direct Parent: Glycerophosphates
• Alternative Parents: Monoalkyl phosphates Secondary alcohols 1,2-diols Primary alcohols Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Sn-glycerol-3-phosphate - Monoalkyl phosphate - Alkyl phosphate - Phosphoric acid ester - Organic phosphoric acid derivative - Secondary alcohol - 1,2-diol - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Primary alcohol - Organooxygen compound - Alcohol - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as glycerophosphates. These are compounds containing a glycerol linked to a phosphate group.
• External Descriptors: sn-glycerol 3-phosphates - glycerol 1-phosphate

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(non-human)

Plasmodium falciparum (966862 Activities)

Explore this target

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Solubility: H2O: 50 mg/mL (271.83 mM; Ultrasonic-assisted dissolution)
• Sensitivity: Moisture sensitive
• Molecular Weight: 172.070 g/mol
• XLogP3: -2.900
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 172.014 Da
• Monoisotopic Mass: 172.014 Da
• Topological Polar Surface Area: 107.000 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 129.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

References

1. Ming-Yan Wang, Meng-Xu Yi, Xing-Yu Mo, Shan-Jie Wei, Yu Qiao, Zheng Zhang, Zhao-Liang Su, Hong-Yan Lu.  (2024)  Over-activation of iNKT cells aggravate lung injury in bronchopulmonary dysplasia mice.  Redox Biology,      [PMID:39342744] [10.1016/j.redox.2024.103370]