Sutezolid - ≥99% , 70S ribosome inhibitor, CAS No.168828-58-8, 70S ribosome inhibitor

Name: Sutezolid - ≥99% , 70S ribosome inhibitor, CAS No.168828-58-8, 70S ribosome inhibitor
Brand: Aladdin Scientific
SKU: S650066
Availability: InStock

CAS: 168828-58-8 Cat. No.: S650066 Molecular Weight: 353.41 EC Number: 809-216-7 PubChem CID: 465951

COA

Skip to the end of the images gallery

Sutezolid - ≥99% CAS No(168828-58-8) by Aladdin Scientific

Skip to the beginning of the images gallery

AVAILABLE TO ORDER

GRADE & PURITY ≥99%

Synonyms

NH-125; NH 125;eEF-2 Kinase Inhibitor, NH125 | SUTEZOLID [WHO-DD] | Sutezolid (USAN/INN) | U-480 | Oxazolidininone | DTXSID20168611 | HY-10251 | AS-74370 | 9EN | cis-3-(Benzyloxymethyl)cyclobutanol, 97% | HY-10392 | N-{[(5S)-3-[3-FLUORO-4-(THIOMORPHOLIN-4

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview Specifications Product Properties Names and Identifiers Documentation Advanced Data Taxonomic Classification 3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solution Calculators Reviews

🧪

Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

In Vivo

Sutezolid (PNU-100480) is a thiomorpholinyl analog of linezolid with superior efficacy against M. tuberculosis in the hollow-fiber, mouse, and whole-blood models. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

IC50& Target:Oxazolidinone

Specifications

Synonyms

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Sutezolid (PNU-100480), an active oxazolidinone antimicrobial agent, acts by inhibiting bacterial protein synthesis . Sutezolid has potent activity against mycobacteria , and is used for the research of drug-resistant tuberculosis.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Mechanism of action

70S ribosome inhibitor

Purity

≥99%

Product Properties

ALogP	1.5

Names and Identifiers

Canonical Smiles	CC(=O)NCC1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCSCC3)F
IUPAC Name	N-[[(5S)-3-(3-fluoro-4-thiomorpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl]acetamide
InChIKey	FNDDDNOJWPQCBZ-ZDUSSCGKSA-N
INCHI	1S/C16H20FN3O3S/c1-11(21)18-9-13-10-20(16(22)23-13)12-2-3-15(14(17)8-12)19-4-6-24-7-5-19/h2-3,8,13H,4-7,9-10H2,1H3,(H,18,21)/t13-/m0/s1
Isomeric SMILES	CC(=O)NC[C@H]1CN(C(=O)O1)C2=CC(=C(C=C2)N3CCSCC3)F
PubChem CID	465951
Molecular Weight	353.41

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Class Thiazinanes
    - Subclass Thiomorpholines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Class	Thiazinanes
Subclass	Thiomorpholines
Intermediate Tree Nodes	Not available
Direct Parent	Phenylthiomorpholines
Alternative Parents	Aniline and substituted anilines Dialkylarylamines Fluorobenzenes Oxazolidinones Aryl fluorides Acetamides Carbamate esters Secondary carboxylic acid amides Organic carbonic acids and derivatives Dialkylthioethers Azacyclic compounds Oxacyclic compounds Hydrocarbon derivatives Organofluorides Organopnictogen compounds Carbonyl compounds Organic oxides
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	4-phenylthiomorpholine - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aniline or substituted anilines - Fluorobenzene - Halobenzene - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Benzenoid - Oxazolidinone - Acetamide - Carbamic acid ester - Oxazolidine - Carboxamide group - Amino acid or derivatives - Tertiary amine - Carbonic acid derivative - Secondary carboxylic acid amide - Oxacycle - Azacycle - Dialkylthioether - Carboxylic acid derivative - Thioether - Organic oxygen compound - Organic oxide - Amine - Hydrocarbon derivative - Carbonyl group - Organopnictogen compound - Organohalogen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Aromatic heteromonocyclic compound
Description	This compound belongs to the class of organic compounds known as phenylthiomorpholines. These are compounds containing a thiomorpholine ring conjugated to a phenyl group. Thiomorpholine a six-membered aliphatic ring containing one nitrogen atom and one sulfur atom at positions 1 and 4 respectively, and four carbon atoms.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

3D Structure

Associated Targets(Human)

MAOB Tclin Amine oxidase [flavin-containing] B (1 Activities)

Discover Target: MAOB

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

MAOA Tclin Monoamine oxidase A (11911 Activities)

Discover Target: MAOA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MAOB Tclin Monoamine oxidase B (8835 Activities)

Discover Target: MAOB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)

Discover Target: CYP3A4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

MT4 (17854 Activities)

Lot Number	Certificate Type	Date	Item
I2411275	Certificate of Analysis	Jul 26, 2024	S650066
I2411276	Certificate of Analysis	Jul 26, 2024	S650066
I2411277	Certificate of Analysis	Jul 26, 2024	S650066
I2411278	Certificate of Analysis	Jul 26, 2024	S650066
I2411279	Certificate of Analysis	Jul 26, 2024	S650066
I2411280	Certificate of Analysis	Jul 26, 2024	S650066
I2411281	Certificate of Analysis	Jul 26, 2024	S650066
I2411282	Certificate of Analysis	Jul 26, 2024	S650066
I2411283	Certificate of Analysis	Jul 26, 2024	S650066
I2411284	Certificate of Analysis	Jul 26, 2024	S650066

Solubility	DMSO : 50 mg/mL (141.48 mM; Need ultrasonic)
Molecular Weight	353.400 g/mol
XLogP3	1.500
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	4
Exact Mass	353.121 Da
Monoisotopic Mass	353.121 Da
Topological Polar Surface Area	87.200 Å²
Heavy Atom Count	24
Formal Charge	0
Complexity	475.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Sutezolid - ≥99% , 70S ribosome inhibitor, CAS No.168828-58-8, 70S ribosome inhibitor

Why this grade

Storage & shipping

Quality documents

Literature proof

Overview

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Customer Reviews

View related series

Related Products