Determine the necessary mass, volume, or concentration for preparing a solution.
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Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 26 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Tamoxifen has been used to facilitate the recombination of ect2flox allele in mouse organs91. It has also been used to study its effect on lipopolysaccharide (LPS)-induced microglial activation92.
| Pubchem Sid | 488192407 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488192407 |
| Canonical Smiles | CCC(=C(C1=CC=CC=C1)C2=CC=C(C=C2)OCCN(C)C)C3=CC=CC=C3 |
| IUPAC Name | 2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine |
| InChIKey | NKANXQFJJICGDU-QPLCGJKRSA-N |
| INCHI | 1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25- |
| Isomeric SMILES | CC/C(=C(\C1=CC=CC=C1)/C2=CC=C(C=C2)OCCN(C)C)/C3=CC=CC=C3 |
| WGK Germany | 3 |
| RTECS | KR5919600 |
| Alternate CAS | 10540-29-1,54965-24-1 (citrate) |
| NSC Number | 727681 |
| MeSH Entry Terms | Citrate, Tamoxifen;ICI 46,474;ICI 46474;ICI 47699;ICI-46,474;ICI-46474;ICI-47699;ICI46,474;ICI46474;ICI47699;Nolvadex;Novaldex;Soltamox;Tamoxifen;Tamoxifen Citrate;Tomaxithen;Zitazonium |
| Molecular Weight | 371.51 |
| Reaxy-Rn | 2062019 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2062019&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Class | Stilbenes |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Stilbenes |
| Alternative Parents | Diphenylmethanes Phenylpropanes Phenoxy compounds Phenol ethers Alkyl aryl ethers Trialkylamines Organopnictogen compounds Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Stilbene - Diphenylmethane - Phenylpropane - Phenoxy compound - Phenol ether - Alkyl aryl ether - Benzenoid - Monocyclic benzene moiety - Tertiary aliphatic amine - Tertiary amine - Ether - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Amine - Organic oxygen compound - Aromatic homomonocyclic compound |
| Description | This compound belongs to the class of organic compounds known as stilbenes. These are organic compounds containing a 1,2-diphenylethylene moiety. Stilbenes (C6-C2-C6 ) are derived from the common phenylpropene (C6-C3) skeleton building block. The introduction of one or more hydroxyl groups to a phenyl ring lead to stilbenoids. |
| External Descriptors | tertiary amino compound - stilbenoid |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 02, 2026 | T137974 | |
| Certificate of Analysis | Feb 27, 2026 | T137974 | |
| Certificate of Analysis | Feb 27, 2026 | T137974 | |
| Certificate of Analysis | Feb 27, 2026 | T137974 | |
| Certificate of Analysis | Jul 25, 2025 | T137974 | |
| Certificate of Analysis | Jul 25, 2025 | T137974 | |
| Certificate of Analysis | Jul 25, 2025 | T137974 | |
| Certificate of Analysis | Jul 25, 2025 | T137974 | |
| Certificate of Analysis | Mar 05, 2025 | T137974 | |
| Certificate of Analysis | Mar 05, 2025 | T137974 | |
| Certificate of Analysis | Nov 29, 2024 | T137974 | |
| Certificate of Analysis | Nov 29, 2024 | T137974 | |
| Certificate of Analysis | Nov 29, 2024 | T137974 | |
| Certificate of Analysis | Nov 29, 2024 | T137974 | |
| Certificate of Analysis | Sep 26, 2024 | T137974 | |
| Certificate of Analysis | Sep 26, 2024 | T137974 | |
| Certificate of Analysis | Sep 26, 2024 | T137974 | |
| Certificate of Analysis | Jun 21, 2024 | T137974 | |
| Certificate of Analysis | Jun 21, 2024 | T137974 | |
| Certificate of Analysis | Jun 21, 2024 | T137974 | |
| Certificate of Analysis | Jun 21, 2024 | T137974 | |
| Certificate of Analysis | Jun 21, 2024 | T137974 | |
| Certificate of Analysis | Apr 11, 2024 | T137974 | |
| Certificate of Analysis | Jun 16, 2023 | T137974 | |
| Certificate of Analysis | Jun 16, 2023 | T137974 | |
| Certificate of Analysis | Jun 16, 2023 | T137974 | |
| Certificate of Analysis | Jun 16, 2023 | T137974 | |
| Certificate of Analysis | Jun 16, 2023 | T137974 | |
| Certificate of Analysis | Jun 16, 2023 | T137974 | |
| Certificate of Analysis | Sep 14, 2022 | T137974 | |
| Certificate of Analysis | Sep 14, 2022 | T137974 | |
| Certificate of Analysis | Sep 14, 2022 | T137974 |
| Solubility | Solvent:ethanol, Max Conc. mg/mL: 37.15, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 7.43, Max Conc. mM: 20 |
|---|---|
| Sensitivity | Light sensitive. |
| Melt Point(°C) | 97-98 °C (lit.) |
| Molecular Weight | 371.500 g/mol |
| XLogP3 | 7.100 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 8 |
| Exact Mass | 371.225 Da |
| Monoisotopic Mass | 371.225 Da |
| Topological Polar Surface Area | 12.500 Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 463.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
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| 16. Yuan-yuan Zhai, Qiang Wang, Qi-yao Nong, Mei-yu Gao, Ying Zhang, Qin-wen Xiao, Yuan Tian, Zun-jian Zhang, Feng-guo Xu, Pei Zhang. (2025) Pitavastatin overcomes multi-drug resistance in CRC and NSCLC by targeting the NRP1-ZFX axis. BIOCHEMICAL PHARMACOLOGY, [PMID:40684995] [10.1016/j.bcp.2025.117183] |
| 17. Daoming Chen, Zhou Yu, Wenbo Wu, Yingxue Du, Qianqian Du, Huanwei Huang, Yaqi Li, Ting Xuan, Ya-Chen Liang, Yang Liu, Zijuan Wang, Rina Su, Yi Zhao, Qi Li, Minmin Luo, Fengchao Wang, Ji Li, Cheng-Ming Chuong, Zhimiao Lin, Ting Chen. (2025) Fibroblast bioelectric signaling drives hair growth. CELL, [PMID:40818454] [10.1016/j.cell.2025.07.035] |
| 18. Tao Qin, Tao Jiang, Zihan Zhou, Mengyuan Wu, Yuanzhen Zhang, Zhenqi Yang, Ziyang Zheng, Jiang Yi, Xiaowei Wang, Mingran Luo, Peng Gao, Jiayun Liu, Yifan Huang, Hao Liu, Qingqing Li, Wei Zhou, Shujun Zhang, Xiaodong Guo, Baorong He, Yongxiang Wang, Jin Fan, Shujie Zhao, Jian Chen, Guoyong Yin. (2025) Treg-microglia partnership in the injured spinal cord preserves Treg cell function and regulates microglial cholesterol metabolism. NEURON, [PMID:41027425] [10.1016/j.neuron.2025.09.001] |
| 19. Zhang Jingjing, Tang Yuyi, Zhang Shan, Xie Zhuxin, Ma Wenrui, Liu Shaowen, Fang Yixuan, Zheng Shufen, Huang Ce, Yan Guoquan, Abudupataer Mieradilijiang, Xin Yue, Zhu Jingqiao, Han Wenjing, Wang Weizhong, Shen Fenglin, Lai Hao, Liu Yang, Ye Dan, Yu Fa-Xing, Xu Yanhui, Pan Cuiping, Wang Chunsheng, Zhu Kai, Zhang Weijia. (2025) Mitochondrial NAD+ deficiency in vascular smooth muscle impairs collagen III turnover to trigger thoracic and abdominal aortic aneurysm. Nature Cardiovascular Research, [PMID:39843801] [10.1038/s44161-024-00606-w] |
| 20. He Hua, Ma Chong, Wei Wei, Wang Haonan, Lai Yutian, Liu Ming, Sun Shenfei, Ma Qing, Lai Jiashuang, Liu Hanxiang, Liu Hanmin, Sun Fei, Lin Xinhua. (2025) Heparan sulfate regulates myofibroblast heterogeneity and function to mediate niche homeostasis during alveolar morphogenesis. Nature Communications, 16 (1): (1-17). [PMID:39979343] [10.1038/s41467-025-57163-4] |
| 21. Mi Zhou, Jiahuan Hong, Xiaofeng Qiu, Zixian Xiong, Xiaoyong Liu, Zhuan Qin, Zhesi Luo, Qi Chen, Mianjie Lin, Ling Min, Xiaorong Yang, Xinmin Guo, Bin Xu, Jianwen Mao. (2025) Serum-derived extracellular vesicles mediate acquired multidrug resistance of MCF-7 breast cancer cells induced by chemotherapeutic drugs. BIOCHEMICAL PHARMACOLOGY, [PMID:40194604] [10.1016/j.bcp.2025.116923] |
| 22. Zemin Liu, Mingxin Sun, Hongjie Zhou, Liben Cheng, Xiaoli Li, Bin Chen, Chaoqi Wang, Chao Li, Dong Wang, Yan Li, Juan Li, Yonghong Zhang. (2025) Osteocytic FSH inhibition rescues bone mass and boosts fracture healing in ovariectomized mice. LIFE SCIENCES, [PMID:41317982] [10.1016/j.lfs.2025.124121] |
| 23. Yijing Zhang, Han Gao, Aiwen Tang, Haiwen Lyu, Zongmin Fan, Jiahui Guo, Yuzhi Wang, Hairong Yi, Qihao Pan, Haidan Luo, Baifu Qin, Boyu Zhang, Xiangqi Meng, Qingxin Liu, Mong-Hong Lee. (2025) CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1-Mediated Ubiquitination of NPM1. Advanced Science, [PMID:41114465] [10.1002/advs.202510210] |
| 24. HuiNa Yang, Qiao Peng, Ruonan Shuang, Zihang Guo, Hao Yang, Chang Chen, Weiwei Tao, Li Liu. (2025) Banxia Houpo Decoction reduces lysosomal leakage of prefrontal astrocytes through the OGT-CTSB-NLRP3 pathway to improve depressive-like behaviors. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:41391522] [10.1016/j.jep.2025.121024] |
| 25. Teng Teng, Shaofan Yang, Jin Li, Haoyu Wang, Fengjuan Wu, Yong He, Jihua Fan, Hongwei Shi, Mingzhu Huang, Xiang Zhou, Ying Liu, Mingyue Gong, Chuanyan Yang, Huiquan Wang, Zhenlu Cai, Hongli Li, Kuan Zhang. (2025) Astrocytic α7-nicotinic acetylcholine receptors mediate pain information processing and perception. NEUROBIOLOGY OF DISEASE, [PMID:41453579] [10.1016/j.nbd.2025.107245] |
| 26. Lingling Qiu, Yajie Zhang, Yushi Tang, Hongli Hu, Ying Zhang, Junwen Xue, Hao Wang, Yecheng Wang, Chunfeng Liu, Jia Jia, Jian Cheng, Yongjun Cao. (2026) Inhibition of SLC11A1-Mediated Lysosomal Iron Accumulation in Microglia Promotes Repair Following White Matter Stroke. Advanced Science, [PMID:41580979] [10.1002/advs.202511482] |
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