trans-Zeatin - Moligand™,10mM in DMSO , CAS No.1637-39-4

CAS: 1637-39-4 Cat. No.: T422013 Molecular Weight: 219.24 Beilstein Registry Number: 616241 EC Number: 605-343-5

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

CHEBI:5583 | AKOS037643348 | HY-19700A | (2Z)-2-methyl-4-[(7H-purin-6-yl)amino]but-2-en-1-ol | A806205 | CCG-266716 | (2Z)-2-methyl-4-(9H-purin-6-ylamino)-2-buten-1-ol | AC-22388 | MFCD00213654 | 7I6OOJ9GR6 | BCP13132 | (2E)-2-methyl-4-[(7H-purin-6-yl)ami

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

trans-Zeatin contains a hydroxylated isoprenoid side chain.

Specifications

Synonyms

CHEBI:5583 | AKOS037643348 | HY-19700A | (2Z)-2-methyl-4-[(7H-purin-6-yl)amino]but-2-en-1-ol | A806205 | CCG-266716 | (2Z)-2-methyl-4-(9H-purin-6-ylamino)-2-buten-1-ol | AC-22388 | MFCD00213654 | 7I6OOJ9GR6 | BCP13132 | (2E)-2-methyl-4-[(7H-purin-6-yl)ami

Specifications & Purity

Moligand™, 10mM in DMSO

Biochemical and Physiological Mechanisms

trans-Zeatin-riboside is a plant cytokinin.Endogenous plant growth hormone. Cytokinin. Potent AHK3 ligand (K i = 1.3 nM). Senescence-delaying hormone. Acts as a positional cue regulating lateral root spacing. Mediates plant growth and development in vivo.

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Names and Identifiers

• Canonical Smiles: CC(=CCNC1=NC=NC2=C1NC=N2)CO
• IUPAC Name: (E)-2-methyl-4-(7H-purin-6-ylamino)but-2-en-1-ol
• InChIKey: UZKQTCBAMSWPJD-FARCUNLSSA-N
• INCHI: 1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+
• Isomeric SMILES: C/C(=C\CNC1=NC=NC2=C1NC=N2)/CO
• WGK Germany: 3
• RTECS: EM9506000
• Molecular Weight: 219.24
• Beilstein: 616241
• Reaxy-Rn: 18499478
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18499478&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Imidazopyrimidines
      • Subclass Purines and purine derivatives
        • Level5 6-aminopurines
          • Level6 6-alkylaminopurines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Imidazopyrimidines
• Subclass: Purines and purine derivatives
• Intermediate Tree Nodes: 6-aminopurines
• Direct Parent: 6-alkylaminopurines
• Alternative Parents: Secondary alkylarylamines Aminopyrimidines and derivatives Imidolactams Imidazoles Heteroaromatic compounds Azacyclic compounds Primary alcohols Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 6-alkylaminopurine - Aminopyrimidine - Secondary aliphatic/aromatic amine - Pyrimidine - Imidolactam - Azole - Imidazole - Heteroaromatic compound - Secondary amine - Azacycle - Organopnictogen compound - Organic oxygen compound - Primary alcohol - Organooxygen compound - Organonitrogen compound - Amine - Alcohol - Hydrocarbon derivative - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as 6-alkylaminopurines. These are compounds that contain an alkylamine group attached at the 6-position of a purine. Purine is a bicyclic aromatic compound made up of a pyrimidine ring fused to an imidazole ring.
• External Descriptors: zeatin

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Associated Targets(Human)

TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)

Discover Target: TSHR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PTH1R Tclin Parathyroid hormone receptor (47172 Activities)

Discover Target: PTH1R

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)

Discover Target: APEX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

BRD4 Tchem Bromodomain-containing protein 4 (13122 Activities)

Discover Target: BRD4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

RECQL Tbio ATP-dependent DNA helicase Q1 (5575 Activities)

Discover Target: RECQL

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Amaranthus (163 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Nicotiana tabacum (382 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Triticum aestivum (1582 Activities)

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Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

lef Anthrax lethal factor (7585 Activities)

Discover Target: lef

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

AHK4 Histidine kinase (36 Activities)

Discover Target: AHK4

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CKX2 Cytokinin dehydrogenase 2 (21 Activities)

Discover Target: CKX2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mechanisms of Action

Chemical and Physical Properties

• Sensitivity: Light sensitive；Air sensitive
• Melt Point(°C): 210°C
• Molecular Weight: 219.240 g/mol
• XLogP3: 0.700
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 219.112 Da
• Monoisotopic Mass: 219.112 Da
• Topological Polar Surface Area: 86.700 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 258.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 1

References

1. Zan Li, Jun Jia, Mingwei Wang, Hua Zhang, Hongyuan Yan, Fengxia Qiao.  (2017)  Bifunctionalized ordered mesoporous organosilica synthesized in deep eutectic solvent for extraction of triazine herbicides from watermelon.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:29132822] [10.1016/j.chroma.2017.10.074]

2. Yong-Lan Ma, Min Li, Qian Lei, Hai-Jun Ma, Ya-Jing An.  (2025)  Trans-Zeatin Enhances Auxenochlorella pyrenoidosa Growth by Coordinating Carbon–Nitrogen Metabolism and Antioxidant Defense.  Microorganisms,  13  (11): (2554).  [PMID:41304239] [10.3390/microorganisms13112554]