2,5-Pyridinedicarboxylic acid - ≥98% , CAS No.100-26-5

CAS: 100-26-5 Cat. No.: P106867 Molecular Weight: 167.12 Beilstein Registry Number: 131697 EC Number: 202-834-2
AVAILABLE TO ORDER
GRADE & PURITY ≥98%
Synonyms
6-carboxy-nicotinic acid | 1189695-39-3 | AM20050593 | FG-0457 | SY007555 | F0001-0013 | 2,5-Pyridinedicarboxylic acid | AB00376873-03 | pyridine carboxylate, 6b | AKOS000119637 | NCGC00336418-01 | W-204355 | Pyridinedicarboxylic acid-(2,5)
Storage
Room temperature
Shipped In
Normal
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5g
P106867-5g
10
$9.90
25g
P106867-25g
8
$19.90
100g
P106867-100g
5
$69.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Room temperature Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 8 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

2,5-Pyridinedicarboxylic acid is used to prepare new 2,5-pyridinedicarboxylic acid derivatives as antiviral agents.
An intermediate for antiviral agents.

2,5-Pyridinedicarboxylic acid can be used:

• In the synthesis of diorganotin(IV) 2,5-pyridinedicarboxylates.

• In the preparation of three-dimensional coordination polymers of lanthanide 2,5-pyridinedicarboxylates by hydrothermal method.

• As an organocatalyst in the synthesis of 1,5-benzodiazepine derivatives via one pot three-component reaction.

Specifications

Synonyms
6-carboxy-nicotinic acid | 1189695-39-3 | AM20050593 | FG-0457 | SY007555 | F0001-0013 | 2, 5-Pyridinedicarboxylic acid | AB00376873-03 | pyridine carboxylate, 6b | AKOS000119637 | NCGC00336418-01 | W-204355 | Pyridinedicarboxylic acid-(2, 5)
Specifications & Purity
≥98%
Storage
Room temperature
Shipped In
Normal
Purity
≥98%
Names and Identifiers
Pubchem Sid488180462
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488180462
Canonical SmilesC1=CC(=NC=C1C(=O)O)C(=O)O
IUPAC Namepyridine-2,5-dicarboxylic acid
InChIKeyLVPMIMZXDYBCDF-UHFFFAOYSA-N
INCHI1S/C7H5NO4/c9-6(10)4-1-2-5(7(11)12)8-3-4/h1-3H,(H,9,10)(H,11,12)
Isomeric SMILES C1=CC(=NC=C1C(=O)O)C(=O)O
WGK Germany 3
Molecular Weight 167.12
Beilstein 131697
Reaxy-Rn 131697
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=131697&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassPyridines and derivatives
SubclassPyridinecarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentPyridinecarboxylic acids
Alternative Parents Dicarboxylic acids and derivatives  Heteroaromatic compounds  Carboxylic acids  Azacyclic compounds  Organopnictogen compounds  Organooxygen compounds  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Pyridine carboxylic acid - Dicarboxylic acid or derivatives - Heteroaromatic compound - Azacycle - Carboxylic acid - Carboxylic acid derivative - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aromatic heteromonocyclic compound
DescriptionThis compound belongs to the class of organic compounds known as pyridinecarboxylic acids. These are compounds containing a pyridine ring bearing a carboxylic acid group.
External Descriptors pyridinedicarboxylic acid
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
ALOX5 Tclin Arachidonate 5-lipoxygenase (6568 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TYR Tclin Tyrosinase (717 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGLN2 Tclin Hypoxia-inducible factor prolyl hydroxylase 1 (404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP3 Tchem Matrix metalloproteinase 3 (3433 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP8 Tchem Matrix metalloproteinase 8 (1942 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P4HTM Tchem Hypoxia-inducible factor prolyl 4-hydroxylase (111 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MMP1 Tchem Matrix metalloproteinase-1 (7046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGLN1 Tclin Egl nine homolog 1 (1702 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EGLN3 Tclin Egl nine homolog 3 (250 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P4HA1 Tchem Prolyl 4-hydroxylase subunit alpha-1 (16 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
blaZ Beta-lactamase (285 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Nos2 Nitric oxide synthase, inducible (3573 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp2 Matrix metalloproteinase-2 (12 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mmp9 Matrix metalloproteinase 9 (38 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
P4ha1 Prolyl 4-hydroxylase alpha-1 subunit (36 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Beta-lactamase L1 (242 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

19 results found

Lot NumberCertificate TypeDateItem
C2611675Certificate of AnalysisFeb 26, 2026 P106867
F2612155Certificate of AnalysisFeb 26, 2026 P106867
C2611710Certificate of AnalysisFeb 26, 2026 P106867
C2611709Certificate of AnalysisFeb 26, 2026 P106867
J2511630Certificate of AnalysisSep 19, 2025 P106867
J2511631Certificate of AnalysisSep 19, 2025 P106867
J2511632Certificate of AnalysisSep 19, 2025 P106867
J2126187Certificate of AnalysisAug 11, 2025 P106867
D2515459Certificate of AnalysisApr 02, 2025 P106867
D2515460Certificate of AnalysisApr 02, 2025 P106867
D2529303Certificate of AnalysisApr 02, 2025 P106867
D2324720Certificate of AnalysisAug 08, 2022 P106867
D2426043Certificate of AnalysisAug 08, 2022 P106867
A2411005Certificate of AnalysisAug 08, 2022 P106867
I2214246Certificate of AnalysisAug 08, 2022 P106867
I2214248Certificate of AnalysisAug 08, 2022 P106867
I2214251Certificate of AnalysisAug 08, 2022 P106867
J2429111Certificate of AnalysisAug 08, 2022 P106867
J2429112Certificate of AnalysisAug 08, 2022 P106867

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Chemical and Physical Properties
Melt Point(°C)254 °C
Molecular Weight167.120 g/mol
XLogP30.200
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass167.022 Da
Monoisotopic Mass167.022 Da
Topological Polar Surface Area87.500 Ų
Heavy Atom Count12
Formal Charge0
Complexity204.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Citations of This Product
References
1. Zhiyuan Liu, Linmeng Wang, Changan Wang, Rushuo Li, Peiyun Zhou, Hongyi Gao, Ge Wang.  (2023)  Modulating the strong metal-support interactions by regulating the chemical microenvironment of Pt confined in MOFs for low temperature hydrogenation of DCPD.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2023.147601]
2. Li-Qiong He, Zhi-Mei Wang, Yu-Jie Li, Jing Yang, Li-Fu Liao, Xi-Lin Xiao, Yong Liu.  (2022)  A Novel Electrochemical Sensor Modified with a Computer-Simulative Magnetic Ion-Imprinted Membrane for Identification of Uranyl Ion.  SENSORS,  22  (12): (4410).  [PMID:35746190] [10.3390/s22124410]
3. Shengnan Yin, Changlun Tong.  (2021)  Europium(III)-Modified Silver Nanoparticles as Ratiometric Colorimetric and Fluorescent Dual-Mode Probes for Selective Detection of Dipicolinic Acid in Bacterial Spores and Lake Waters.  ACS Applied Nano Materials,      [PMID:] [10.1021/acsanm.1c00838]
4. Ru-Ru Gao, Wei Dong.  (2020)  ATP and lanthanide ions derived coordination polymer nanoparticles as a novel family of versatile materials: Color-tunable emission, artificial tongues and logic devices.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2020.105753]
5. Guo-Cheng Liu, Yan Li, Ying Xiong, Xiang-Xiang Liu, Qiao-Min Li, Ju-Wen Zhang, Hong-Yan Lin, Xiao-Wu Li.  (2018)  Spacers-directed structural diversity of Co(II)/Zn(II) complexes based on S-/O-bridged dipyridylamides: electrochemical, fluorescent recognition behavior and photocatalytic properties.  JOURNAL OF COORDINATION CHEMISTRY,      [PMID:] [10.1080/00958972.2018.1438606]
6. Qingsong Zhang, Yuyang Miao, Jianwei Hu, Haiyi Gong, Yang Xiao, Qingyi Zeng.  (2025)  Modulating the electronic structure of a hydrogen-bonded organic framework to improve the uranium removal by enhancing hydrogen evolution reaction.  Inorganic Chemistry Frontiers,      [PMID:] [10.1039/D4QI02743D]
7. Huifang Wu, Qiqi Wang, Lingfeng Zhu, Haoliang Zhang, Lizhong Liu.  (2025)  Regulating the aromatic structure in carbon dots to enhance the internal filter effect for sensitive on-site monitoring of anthrax biomarkers.  TALANTA,      [PMID:40031139] [10.1016/j.talanta.2025.127854]
8. Feifan Zhang, Jinhui Liang, Hongliang Zhang, Mengqi Duan, Dong Yang, Chamba Yangzom, Peng Shang.  (2025)  Non-Targeted Metabolomics Analysis of Metabolic Differences Between Different Concentrations of Protein Diets in the Longest Dorsal Muscle of Tibetan Pigs.  Metabolites,  15  (8): (555).  [PMID:40863171] [10.3390/metabo15080555]
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