5-HEAT - Moligand™ , Agonist of MT 1 receptor;Antagonist of MT 2 receptor, CAS No.214416-49-6, Agonist of MT 1 receptor;Antagonist of MT 2 receptor

CAS: 214416-49-6 Cat. No.: H607220 PubChem CID: 10849065
AVAILABLE TO ORDER
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
Synonyms
Q27073983 | Acetamide, N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]- | PD047748 | n-{2-[5-(2-hydroxyethoxy)-1h-indol-3-yl]ethyl}acetamide | GTPL1345 | N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]acetamide | 5-HEAT | SCHEMBL6257511 | BDBM50471836 | DTX
Storage
Room temperature
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
H607220-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$799.90
25mg
H607220-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
$1,714.90
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Why this grade

Moligand™ Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature Ships Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
Q27073983 | Acetamide, N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]- | PD047748 | n-{2-[5-(2-hydroxyethoxy)-1h-indol-3-yl]ethyl}acetamide | GTPL1345 | N-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]acetamide | 5-HEAT | SCHEMBL6257511 | BDBM50471836 | DTX
Specifications & Purity
Moligand™
Storage
Room temperature
Grade
Moligand™
Action Type
AGONIST, ANTAGONIST
Mechanism of action
Agonist of MT 1 receptor;Antagonist of MT 2 receptor
Names and Identifiers
Canonical SmilesOCCOc1ccc2c(c1)c(CCNC(=O)C)c[nH]2
IUPAC NameN-[2-[5-(2-hydroxyethoxy)-1H-indol-3-yl]ethyl]acetamide
InChIKeyCZPLTTWZQPLXMQ-UHFFFAOYSA-N
INCHI1S/C14H18N2O3/c1-10(18)15-5-4-11-9-16-14-3-2-12(8-13(11)14)19-7-6-17/h2-3,8-9,16-17H,4-7H2,1H3,(H,15,18)
Isomeric SMILES CC(=O)NCCC1=CNC2=C1C=C(C=C2)OCCO
PubChem CID 10849065

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClassCarboxylic acids and derivatives
SubclassCarboxylic acid derivatives
Intermediate Tree Nodes Carboxylic acid amides - Acetamides
Direct ParentN-acetyl-2-arylethylamines
Alternative Parents 3-alkylindoles  Phenol ethers  Alkyl aryl ethers  Substituted pyrroles  Heteroaromatic compounds  Secondary carboxylic acid amides  Azacyclic compounds  Primary alcohols  Organonitrogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents N-acetyl-2-arylethylamine - 3-alkylindole - Indole - Indole or derivatives - Phenol ether - Alkyl aryl ether - Substituted pyrrole - Benzenoid - Pyrrole - Heteroaromatic compound - Secondary carboxylic acid amide - Ether - Azacycle - Organoheterocyclic compound - Organic nitrogen compound - Alcohol - Primary alcohol - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic oxide - Organic oxygen compound - Carbonyl group - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as n-acetyl-2-arylethylamines. These are compounds containing an acetamide group that is N-linked to an arylethylamine.
External Descriptors Not available
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
MTNR1A Tclin Melatonin receptor type 1A (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MTNR1B Tclin Melatonin receptor type 1B (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MTNR1A Tclin Melatonin receptor 1A (2519 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Melatonin receptor 1B (19 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Melatonin receptor 1C (17 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Solution Calculators
Reviews

Customer Reviews

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