Adenosine 5′-diphosphate cyclohexylammonium salt - Moligand™, ≥95% , CAS No.58-64-0(free basis)

CAS: 58-64-0(free basis) Cat. No.: A498701 Molecular Weight: 427.20 + x(99.17) EC Number: 200-392-5

GRADE & PURITY Moligand™, ≥95%

Synonyms

ADP

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Application:

Adenosine 5 '- diphosphate (ADP) is an adenine nucleotide involved in energy storage and nucleic acid metabolism through the conversion of ATP synthase to ATP. ADP affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. After being converted to adenosine by the ecto ADP enzyme, platelet activation is inhibited by adenosine receptor.

Specifications

Synonyms

ADP

Specifications & Purity

Moligand™, ≥95%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Purity

≥95%

Names and Identifiers

• Molecular Weight: 427.20 + x(99.17)

Associated Targets(Human)

TRPM4 Tchem Transient receptor potential cation channel subfamily M member 4 (1 Activities)

Discover Target: TRPM4

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

HSPA8 Tchem Heat shock cognate 71 kDa protein (4 Activities)

Discover Target: HSPA8

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RY12 Tclin P2Y purinoceptor 12 (1 Activities)

Discover Target: P2RY12

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RY1 Tchem P2Y purinoceptor 1 (3 Activities)

Discover Target: P2RY1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RY6 Tchem P2Y purinoceptor 6 (1 Activities)

Discover Target: P2RY6

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RY13 Tchem P2Y purinoceptor 13 (1 Activities)

Discover Target: P2RY13

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

P2RX1 Tchem P2X purinoceptor 1 (1 Activities)

Discover Target: P2RX1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Chemical and Physical Properties

• Solubility: solubility H2O: soluble, clear to slightly hazy, colorless to faintly yellow

References

1. Guannan Zhang, Anping Zhu, Shihong Wang, Qianshan Chen, Bing Liu, Jun Zhou, Zhaoyang Wu.  (2022)  Stabilizing liquid crystal droplets with hydrogel films and its application in monitoring adenosine triphosphate.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2022.130122]

2. Shun Hu, Xiaona Li, Kai Wang, Qiuhua Wu, Guolin Zhang, Xue Liu.  (2020)  Sensor array based on carbon dots for ATP-related physiological phosphates detecting and ATP hydrolysis monitoring.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2020.127851]

3. Guimei Wang, Xiaoxue Jiang, Nanyan Fu.  (2019)  Near-infrared squaraine fluorescent probe for imaging adenosine 5′-triphosphate in live cells.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2019.107698]

4. Gong Bi, Huang Shuai, Ye Niu, Yuan Xue, Ma Huiling.  (2018)  Pre-harvest ethylene control affects vase life of cut rose ‘Carola’ by regulating energy metabolism and antioxidant enzyme activity.  Horticulture Environment and Biotechnology,  59  (6): (835-845).  [PMID:] [10.1007/s13580-018-0053-8]

5. Pang Jiawei, Lu Yuexiang, Gao Xinyu, Song Panshu, Yang Fengyi, Liu Yueying.  (2018)  On-off-on luminescent pyrophosphate probe based on the use of Mn-doped ZnS quantum dots and using Eu(III) as a mediator.  MICROCHIMICA ACTA,  185  (10): (1-8).  [PMID:30259119] [10.1007/s00604-018-3003-3]

6. Lingzhi Zhao, Liu Zhao, Yanqing Miao, Chunye Liu, Chenxiao Zhang.  (2016)  Construction of a Turn Off-On-Off Fluorescent System Based on Competitive Coordination of Cu2+ between 6,7-Dihydroxycoumarin and Pyrophosphate Ion for Sensitive Assay of Pyrophosphatase Activity.  Journal of Analytical Methods in Chemistry,      [PMID:27766179] [10.1155/2016/4306838]

7. Pei Jin Xie, Ming Li Ye, Zhong Yang Hu, Guang Wen Pan, Yan Zhu, Jia Jie Zhang.  (2011)  Determination of levels of adenosine phosphates in blood by ion chromatography.  CHINESE CHEMICAL LETTERS,      [PMID:] [10.1016/j.cclet.2011.09.008]