BRITE338733 - ≥99% , CAS No.503105-88-2

CAS: 503105-88-2 Cat. No.: B412214 Molecular Weight: 433.59

GRADE & PURITY ≥99%

Synonyms

Phenol,2-​[4-​(5-​ethyl-​2-​furanyl)​-​6-​[(2,​2,​6,​6-​tetramethyl-​4-​piperidinyl)​amino]​-​2-​pyridinyl]​-​4-​methyl-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Overview

Information

BRITE338733 BRITE-338733 is a potent RecA (a DNA-dependent ATPase) inhibitor with IC50 of 4.7 µM.

Targets

RecA (Cell-free assay) 4.7 μM

Specifications

Synonyms

Phenol, 2-​[4-​(5-​ethyl-​2-​furanyl)​-​6-​[(2, ​2, ​6, ​6-​tetramethyl-​4-​piperidinyl)​amino]​-​2-​pyridinyl]​-​4-​methyl-

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

BRITE-338733 is a potent RecA (a DNA-dependent ATPase) inhibitor with IC50 of 4.7 µM.

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

This product requires cold chain shipping. Ground and other economy services are not available.

Action Type

INHIBITOR

Purity

≥99%

Product Properties

• ALogP: 5.684
• hba_count: 2
• HBD Count: 3
• Rotatable Bond: 5

Names and Identifiers

• Pubchem Sid: 488203015
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488203015
• Canonical Smiles: CCC1=CC=C(O1)C2=CC(=NC(=C2)NC3CC(NC(C3)(C)C)(C)C)C4=C(C=CC(=C4)C)O
• IUPAC Name: 2-[4-(5-ethylfuran-2-yl)-6-[(2,2,6,6-tetramethylpiperidin-4-yl)amino]pyridin-2-yl]-4-methylphenol
• InChIKey: PKYYVDCUXJXUPN-UHFFFAOYSA-N
• INCHI: 1S/C27H35N3O2/c1-7-20-9-11-24(32-20)18-13-22(21-12-17(2)8-10-23(21)31)29-25(14-18)28-19-15-26(3,4)30-27(5,6)16-19/h8-14,19,30-31H,7,15-16H2,1-6H3,(H,28,29)
• Molecular Weight: 433.59
• Reaxy-Rn: 61504256
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=61504256&ln=

Chemical and Physical Properties

• Solubility: Solubility (25°C) In vitro DMSO: 87 mg/mL (200.65 mM); Ethanol: 10 mg/mL (23.06 mM); Water: Insoluble
• DMSO(mg / mL) Max Solubility: 87
• DMSO(mM) Max Solubility: 200.650384003321
• Water(mg / mL) Max Solubility: ＜1