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· · COA & SDS available for every product · Same-day shipping on in-stock items CHR-6494 - ≥98% , CAS No.1333377-65-3
Synonyms
FT-0734501 | NCGC00370724-05 | 1333377-65-3 | CHR6494 | CHR-6494 | HY-15217 | BDBM50587785 | DTXSID90742629 | AKOS025149446 | F84874 | A899134 | 3-(1H-Indazol-5-yl)-N-propylimidazo-[1,2-b]pyridazin-6-amine | 3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyrid
Shipped In
Ice chest + Ice pads
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Why this grade ≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
FT-0734501 | NCGC00370724-05 | 1333377-65-3 | CHR6494 | CHR-6494 | HY-15217 | BDBM50587785 | DTXSID90742629 | AKOS025149446 | F84874 | A899134 | 3-(1H-Indazol-5-yl)-N-propylimidazo-[1, 2-b]pyridazin-6-amine | 3-(1H-indazol-5-yl)-N-propylimidazo[1, 2-b]pyrid
Specifications & Purity
≥98%
Biochemical and Physiological Mechanisms
CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. CHR-6494 causes cell cycle arrest in G2/M and subsequent apoptosis. CHR-6494 causes an abnormal duplication of cent
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles CCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1 IUPAC Name 3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine InChIKey CZZCAOGIEGXMBZ-UHFFFAOYSA-N INCHI 1S/C16H16N6/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20) Isomeric SMILES CCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1 Alternate CAS 1458630-17-5 （TFA salt） Molecular Weight 292.34 Reaxy-Rn 29788281 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29788281&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Benzopyrazoles Subclass Indazoles Intermediate Tree Nodes Not available Direct Parent Indazoles Alternative Parents Aminopyridazines N-substituted imidazoles Imidolactams Benzenoids Pyrazoles Heteroaromatic compounds Azacyclic compounds Hydrocarbon derivatives Amines Molecular Framework Aromatic heteropolycyclic compounds Substituents Benzopyrazole - Indazole - Aminopyridazine - N-substituted imidazole - Pyridazine - Benzenoid - Imidolactam - Pyrazole - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organonitrogen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as indazoles. These are compounds containing an indazole, which is structurally characterized by a pyrazole fused to a benzene. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility DMSO Molecular Weight 292.340 g/mol XLogP3 2.800 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 4 Exact Mass 292.144 Da Monoisotopic Mass 292.144 Da Topological Polar Surface Area 70.900 Ų Heavy Atom Count 22 Formal Charge 0 Complexity 378.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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