CP376395 - Moligand™, ≥98% , Antagonist of CRF 1 receptor, CAS No.175140-00-8, Antagonist of CRF 1 receptor

CAS: 175140-00-8 Cat. No.: C412543 분자식: C21H30N2O 분자량: 326.49
주문 가능
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
VIZBSVDBNLAVAW-UHFFFAOYSA-N | BDBM20966 | 5113G7FP34 | UNII-5113G7FP34 | compound 3a [PMID: 18288792] | GTPL3496 | 3,6-Dimethyl-N-(Pentan-3-Yl)-2-(2,4,6-Trimethylphenoxy)pyridin-4-Amine | AKOS015994585 | CP-376,395 | 4k5y | CP 376395 | GD-0065 | CP-376395
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
USA
독일 (EU)*
Price
Qty
5mg
C412543-5mg
3 재고 있음
—
US$148.90
10mg
C412543-10mg
3 재고 있음
—
US$243.90
25mg
C412543-25mg
2 재고 있음
—
US$560.90
50mg
C412543-50mg
2 재고 있음
—
US$811.90
100mg
C412543-100mg
2 재고 있음
—
US$1,301.90
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

개요

Information

CP376395 CP 376395 is a potent and selective antagonist of corticotropin releasing factor 1 (CRF1) receptor.

Specifications

동의어
VIZBSVDBNLAVAW-UHFFFAOYSA-N | BDBM20966 | 5113G7FP34 | UNII-5113G7FP34 | compound 3a [PMID: 18288792] | GTPL3496 | 3,6-Dimethyl-N-(Pentan-3-Yl)-2-(2,4,6-Trimethylphenoxy)pyridin-4-Amine | AKOS015994585 | CP-376,395 | 4k5y | CP 376395 | GD-0065 | CP-376395
사양 및 순도
Moligand™, ≥98%
생화학 및 생리적 메커니즘
CP 376395 is a potent and selective antagonist of corticotropin releasing factor 1 (CRF1) receptor. CP-376395 is a potent and selective antagonist of the CRF1 receptor, which has been shown to play an important role in mediating behavioral and endocrine r
보관 조건
Store at -20°C
배송
Ice chest + Ice pads
이 제품은 콜드 체인 배송이 필요합니다.지상 및 기타 경제 서비스는 사용할 수 없습니다.
등급
Moligand™
작업 유형
ANTAGONIST
작동 메커니즘
Antagonist of CRF 1 receptor
순수함
≥98%
이름과 식별자
Pubchem Sid504765001
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504765001
정식 스마일CCC(CC)NC1=C(C(=NC(=C1)C)OC2=C(C=C(C=C2C)C)C)C
IUPAC Name3,6-dimethyl-N-pentan-3-yl-2-(2,4,6-trimethylphenoxy)pyridin-4-amine
InChIKeyVIZBSVDBNLAVAW-UHFFFAOYSA-N
INCHI1S/C21H30N2O/c1-8-18(9-2)23-19-12-16(6)22-21(17(19)7)24-20-14(4)10-13(3)11-15(20)5/h10-12,18H,8-9H2,1-7H3,(H,22,23)
이성체 SMILES CCC(CC)NC1=C(C(=NC(=C1)C)OC2=C(C=C(C=C2C)C)C)C
분자량 326.49
Reaxy-Rn 13255678
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13255678&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
분류Organooxygen compounds
SubclassEthers
Intermediate Tree Nodes Not available
Direct ParentDiarylethers
Alternative Parents Phenoxy compounds  Phenol ethers  Secondary alkylarylamines  Methylpyridines  Aminopyridines and derivatives  Heteroaromatic compounds  Azacyclic compounds  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents Diaryl ether - Phenoxy compound - Phenol ether - Aminopyridine - Methylpyridine - Secondary aliphatic/aromatic amine - Monocyclic benzene moiety - Pyridine - Benzenoid - Heteroaromatic compound - Organoheterocyclic compound - Azacycle - Secondary amine - Organonitrogen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Aromatic heteromonocyclic compound
설명This compound belongs to the class of organic compounds known as diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups.
External Descriptors Not available
3D 구조
상호 작용 화학 구조 모델





관련 대상(인간)
CRHR1 Tclin Corticotropin-releasing factor receptor 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CRHR1 Tclin Corticotropin releasing factor receptor 1 (2996 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CRHR2 Tchem Corticotropin releasing factor receptor 2 (399 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Liver microsomes (16955 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
관련 대상(비인간)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Canis familiaris (36305 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
작용 메커니즘
인증서(CoA, COO, BSE/TSE 및 분석 차트)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate Type날짜항목
B2308494Certificate of AnalysisNov 19, 2022 C412543
B2308517Certificate of AnalysisNov 19, 2022 C412543
B2308524Certificate of AnalysisNov 19, 2022 C412543
B2308528Certificate of AnalysisNov 19, 2022 C412543
B2308536Certificate of AnalysisNov 19, 2022 C412543
화학 및 물리적 특성
용해성Solubility (25°C) In vitro Ethanol: mg/mL    
분자량326.500 g/mol
XLogP36.400
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count6
Exact Mass326.236 Da
Monoisotopic Mass326.236 Da
Topological Polar Surface Area34.200 Ų
Heavy Atom Count24
Formal Charge0
Complexity359.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
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리뷰

고객 리뷰

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