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· · COA & SDS available for every product · Same-day shipping on in-stock items CP376395 - Moligand™, ≥98% , Antagonist of CRF 1 receptor, CAS No.175140-00-8, Antagonist of CRF 1 receptor
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
VIZBSVDBNLAVAW-UHFFFAOYSA-N | BDBM20966 | 5113G7FP34 | UNII-5113G7FP34 | compound 3a [PMID: 18288792] | GTPL3496 | 3,6-Dimethyl-N-(Pentan-3-Yl)-2-(2,4,6-Trimethylphenoxy)pyridin-4-Amine | AKOS015994585 | CP-376,395 | 4k5y | CP 376395 | GD-0065 | CP-376395
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview Information
CP376395 CP 376395 is a potent and selective antagonist of corticotropin releasing factor 1 (CRF1) receptor.
Specifications Synonyms
VIZBSVDBNLAVAW-UHFFFAOYSA-N | BDBM20966 | 5113G7FP34 | UNII-5113G7FP34 | compound 3a [PMID: 18288792] | GTPL3496 | 3, 6-Dimethyl-N-(Pentan-3-Yl)-2-(2, 4, 6-Trimethylphenoxy)pyridin-4-Amine | AKOS015994585 | CP-376, 395 | 4k5y | CP 376395 | GD-0065 | CP-376395
Specifications & Purity
Moligand™, ≥98%
Biochemical and Physiological Mechanisms
CP 376395 is a potent and selective antagonist of corticotropin releasing factor 1 (CRF1) receptor.
CP-376395 is a potent and selective antagonist of the CRF1 receptor, which has been shown to play an important role in mediating behavioral and endocrine r
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Mechanism of action
Antagonist of CRF 1 receptor
Names and Identifiers Pubchem Sid 504765001 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504765001 Canonical Smiles CCC(CC)NC1=C(C(=NC(=C1)C)OC2=C(C=C(C=C2C)C)C)C IUPAC Name 3,6-dimethyl-N-pentan-3-yl-2-(2,4,6-trimethylphenoxy)pyridin-4-amine InChIKey VIZBSVDBNLAVAW-UHFFFAOYSA-N INCHI 1S/C21H30N2O/c1-8-18(9-2)23-19-12-16(6)22-21(17(19)7)24-20-14(4)10-13(3)11-15(20)5/h10-12,18H,8-9H2,1-7H3,(H,22,23) Isomeric SMILES CCC(CC)NC1=C(C(=NC(=C1)C)OC2=C(C=C(C=C2C)C)C)C Molecular Weight 326.49 Reaxy-Rn 13255678 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=13255678&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic oxygen compounds Class Organooxygen compounds Subclass Ethers Intermediate Tree Nodes Not available Direct Parent Diarylethers Alternative Parents Phenoxy compounds Phenol ethers Secondary alkylarylamines Methylpyridines Aminopyridines and derivatives Heteroaromatic compounds Azacyclic compounds Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Diaryl ether - Phenoxy compound - Phenol ether - Aminopyridine - Methylpyridine - Secondary aliphatic/aromatic amine - Monocyclic benzene moiety - Pyridine - Benzenoid - Heteroaromatic compound - Organoheterocyclic compound - Azacycle - Secondary amine - Organonitrogen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as diarylethers. These are organic compounds containing the dialkyl ether functional group, with the formula ROR', where R and R' are aryl groups. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solubility (25°C) In vitro Ethanol: mg/mL Molecular Weight 326.500 g/mol XLogP3 6.400 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 6 Exact Mass 326.236 Da Monoisotopic Mass 326.236 Da Topological Polar Surface Area 34.200 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 359.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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