D-(+)-Galactosamine hydrochloride - ≥99% , CAS No.1772-03-8

CAS: 1772-03-8 Cat. No.: G115553 Molecular Weight: 215.63 EC Number: 217-198-1

GRADE & PURITY ≥99%

Synonyms

2-Amino-2-deoxy-D-galactopyranose hydrochloride | D-Galactosamine HCl | D-Chondrosamine hydrochloride

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

D-galactosamine (d-GalN) is a specific hepatotoxic agent metabolized particularly in hepatocytes. It is a 6-carbon amino sugar derived from galactose.

Specifications

Synonyms

2-Amino-2-deoxy-D-galactopyranose hydrochloride | D-Galactosamine HCl | D-Chondrosamine hydrochloride

Specifications & Purity

≥99%

Biochemical and Physiological Mechanisms

Lipid peroxidation and apoptosis inducer. Increases triacylglycerol synthesis by inhibiting palmitate oxidation pathway and decreases triacylglycerol secretion. Inhibits oxidation and phosphorylation in liver mitochondria. Hepatotoxic agent.

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥99%

Names and Identifiers

• Pubchem Sid: 488192210
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488192210
• Isomeric SMILES: C([C@@H]1[C@@H]([C@@H]([C@H](C(O1)O)N)O)O)O.Cl
• WGK Germany: 3
• Alternate CAS: 7535-00-4
• Molecular Weight: 215.63

Chemical and Physical Properties

• Solubility: H2O: 50 mg/mL, clear to slightly hazy, colorless to very faintly yellow
• Specific Rotation[α]: +94.0 to +98.0 deg(C=1, H2O)
• Melt Point(°C): 182-185°C
• Molecular Weight: 215.630 g/mol
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 215.056 Da
• Monoisotopic Mass: 215.056 Da
• Topological Polar Surface Area: 116.000 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 155.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

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