IMM-H007 - 10mM in DMSO , CAS No.1221412-23-2

CAS: 1221412-23-2 Cat. No.: I420951 Molecular Weight: 485.45 PubChem CID: 154730591

GRADE & PURITY 10mM in DMSO

Synonyms

Adenosine,N-​(3-​hydroxyphenyl)​-​,2',​3',​5'-​triacetate

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Information

IMM-H007 IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK) . IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signaling. IMM-H007 inhibits ABCA1 (ATP binding cassette subfamily a member 1) degradation and facilitates its cell-surface localization in macrophages, thereby promotes cholesterol efflux.

Targets

AMPK ; NF-κB ; JNK/AP1 ; ABCA1

Specifications

Synonyms

Adenosine, N-​(3-​hydroxyphenyl)​-​, 2', ​3', ​5'-​triacetate

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

IMM-H007, an adenosine derivative, is an activator of AMP-Activated Protein Kinase (AMPK). IMM-H007 is a potential drug for treating cardiac dysfunction. IMM-H007 negatively regulates endothelium inflammation through inactivating NF-κB and JNK/AP1 signali

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Canonical Smiles: CC(=O)OCC1CCC(O1)N2C=NC3=C(N=CN=C32)NC4=CC(=CC=C4)O
• IUPAC Name: [(2R,5R)-5-[6-(3-hydroxyanilino)purin-9-yl]oxolan-2-yl]methyl acetate
• InChIKey: XSGYPRXHHAULBZ-HUUCEWRRSA-N
• INCHI: 1S/C18H19N5O4/c1-11(24)26-8-14-5-6-15(27-14)23-10-21-16-17(19-9-20-18(16)23)22-12-3-2-4-13(25)7-12/h2-4,7,9-10,14-15,25H,5-6,8H2,1H3,(H,19,20,22)/t14-,15-/m1/s1
• PubChem CID: 154730591
• Molecular Weight: 485.45