Serine/threonine-protein kinase 4 (STK4)

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  1. BMS-536924, Inhibitor of CYP3A4;Inhibitor of Insulin-like growth factor I receptor;Inhibitor of Insulin receptor
    CAS: 468740-43-4 Formula: C25H26ClN5O3 Molecular Weight: 479.97
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B126005
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    IUPAC Name
    4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one
    SMILES
    CC1=CC(=CC2=C1N=C(N2)C3=C(C=CNC3=O)NCC(C4=CC(=CC=C4)Cl)O)N5CCOCC5
    InChIKey
    ZWVZORIKUNOTCS-OAQYLSRUSA-N
    InChI
    1S/C25H26ClN5O3/c1-15-11-18(31-7-9-34-10-8-31)13-20-23(15)30-24(29-20)22-19(5-6-27-25(22)33)28-14-21(32)16-3-2-4-17(26)12-16/h2-6,11-13,21,32H,7-10,14show more
    Synonyms
    HY-10262 | N6I | 4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-3-[7-methyl-5-(morpholin-4-yl)-1H-1,3-benzodiazol-...
  2. XMU MP 1, Inhibitor of serine/threonine kinase 3;Inhibitor of serine/threonine kinase 4
    CAS: 2061980-01-4 PubChem CID: 121499143 Formula: C17H16N6O3S2 Molecular Weight: 416.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%(HPLC)
    In Stock Item #: X286918
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    IUPAC Name
    4-[(2,9-dimethyl-8-oxo-6-thia-2,9,12,14-tetrazatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-13-yl)amino]benzenesulfonamide
    SMILES
    CN1C2=C(C(=O)N(C3=CN=C(N=C31)NC4=CC=C(C=C4)S(=O)(=O)N)C)SC=C2
    InChIKey
    YRDHKIFCGOZTGD-UHFFFAOYSA-N
    InChI
    1S/C17H16N6O3S2/c1-22-12-7-8-27-14(12)16(24)23(2)13-9-19-17(21-15(13)22)20-10-3-5-11(6-4-10)28(18,25)26/h3-9H,1-2H3,(H2,18,25,26)(H,19,20,21)
    Synonyms
    4-[(6,10-Dihydro-5,10-dimethyl-6-oxo-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino]benzenesulfonamide | 4-(...
  3. (3R,4S)-Tofacitinib
    CAS: 1092578-46-5 PubChem CID: 25180101 Formula: C16H20N6O Molecular Weight: 312.37
    Solid ≥98%
    In Stock Item #: T126415
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    IUPAC Name
    3-[(3R,4S)-4-methyl-3-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile
    SMILES
    CC1CCN(CC1N(C)C2=NC=NC3=C2C=CN3)C(=O)CC#N
    InChIKey
    UJLAWZDWDVHWOW-AAEUAGOBSA-N
    InChI
    1S/C16H20N6O/c1-11-5-8-22(14(23)3-6-17)9-13(11)21(2)16-12-4-7-18-15(12)19-10-20-16/h4,7,10-11,13H,3,5,8-9H2,1-2H3,(H,18,19,20)/t11-,13-/m0/s1
    Synonyms
    UNII-B64WR5WNB7 | D86134 | (3R,4S)-4-Methyl-3-(methyl-7H-pyrrolo(2,3-d)pyrimidin-4-ylamino)-beta-oxo-1-piperidineprop...
  4. BMS-536924, Inhibitor of CYP3A4;Inhibitor of Insulin-like growth factor I receptor;Inhibitor of Insulin receptor
    CAS: 468740-43-4 Formula: C25H26ClN5O3 Molecular Weight: 479.97
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: B424098
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    IUPAC Name
    4-[[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino]-3-(4-methyl-6-morpholin-4-yl-1H-benzimidazol-2-yl)-1H-pyridin-2-one
    SMILES
    CC1=CC(=CC2=C1N=C(N2)C3=C(C=CNC3=O)NCC(C4=CC(=CC=C4)Cl)O)N5CCOCC5
    InChIKey
    ZWVZORIKUNOTCS-OAQYLSRUSA-N
    InChI
    1S/C25H26ClN5O3/c1-15-11-18(31-7-9-34-10-8-31)13-20-23(15)30-24(29-20)22-19(5-6-27-25(22)33)28-14-21(32)16-3-2-4-17(26)12-16/h2-6,11-13,21,32H,7-10,14show more
    Synonyms
    HY-10262 | N6I | 4-{[(2S)-2-(3-chlorophenyl)-2-hydroxyethyl]amino}-3-[7-methyl-5-(morpholin-4-yl)-1H-1,3-benzodiazol-...
  5. PF-06447475, Inhibitor of leucine rich repeat kinase 2
    CAS: 1527473-33-1 EC Number: 808-609-0 PubChem CID: 72706840 Formula: C17H15N5O Molecular Weight: 305.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    In Stock Item #: P413944
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    IUPAC Name
    3-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile
    SMILES
    C1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N
    InChIKey
    BHTWDJBVZQBRKP-UHFFFAOYSA-N
    InChI
    1S/C17H15N5O/c18-9-12-2-1-3-13(8-12)14-10-19-16-15(14)17(21-11-20-16)22-4-6-23-7-5-22/h1-3,8,10-11H,4-7H2,(H,19,20,21)
    Synonyms
    3FE | PF 06447475 | BDBM50059277 | 3-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile | CCG-267523 | 3-...
  6. PF-06447475, Inhibitor of leucine rich repeat kinase 2
    CAS: 1527473-33-1 EC Number: 808-609-0 PubChem CID: 72706840 Formula: C17H15N5O Molecular Weight: 305.33
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: P421809
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    Technical Identifiers
    IUPAC Name
    3-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile
    SMILES
    C1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N
    InChIKey
    BHTWDJBVZQBRKP-UHFFFAOYSA-N
    InChI
    1S/C17H15N5O/c18-9-12-2-1-3-13(8-12)14-10-19-16-15(14)17(21-11-20-16)22-4-6-23-7-5-22/h1-3,8,10-11H,4-7H2,(H,19,20,21)
    Synonyms
    3FE | PF 06447475 | BDBM50059277 | 3-(4-morpholin-4-yl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile | CCG-267523 | 3-...
  7. XMU-MP-1, Inhibitor of serine/threonine kinase 3;Inhibitor of serine/threonine kinase 4
    CAS: 2061980-01-4 PubChem CID: 121499143 Formula: C17H16N6O3S2 Molecular Weight: 416.48
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    In Stock Item #: X408533
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    Technical Identifiers
    Synonyms
    4-((5,10-dimethyl-6-oxo-6,10-dihydro-5H-pyrimido[5,4-b]thieno[3,2-e][1,4]diazepin-2-yl)amino)benzenesulfonamide
  8. IHMT-MST1-58, Inhibitor of serine/threonine kinase 4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: I610968
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    IUPAC Name
    4-[[5,8-dimethyl-7-(2-methylphenyl)-6-oxo-7H-pteridin-2-yl]amino]benzenesulfonamide
    SMILES
    CN1c2cnc(Nc3ccc(S(=O)(=O)N)cc3)nc2N(C)C(c2ccccc2C)C1=O
    InChIKey
    FWEIAKDAIDQPRK-UHFFFAOYSA-N
    InChI
    1S/C21H22N6O3S/c1-13-6-4-5-7-16(13)18-20(28)26(2)17-12-23-21(25-19(17)27(18)3)24-14-8-10-15(11-9-14)31(22,29)30/h4-12,18H,1-3H3,(H2,22,29,30)(H,23,24,show more
    Synonyms
    compound 19
  9. SBP-3264, Inhibitor of serine/threonine kinase 3;Inhibitor of serine/threonine kinase 4
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.
    Out of Stock Item #: S613473
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    Technical Identifiers
    SMILES
    Clc1cccc(c2c[nH]c3ncnc(N4CCC(NC(=O)C)CC4)c23)c1
    InChIKey
    AYRVYPOFYQSRNH-UHFFFAOYSA-N
    InChI
    1S/C19H20ClN5O/c1-12(26)24-15-5-7-25(8-6-15)19-17-16(10-21-18(17)22-11-23-19)13-3-2-4-14(20)9-13/h2-4,9-11,15H,5-8H2,1H3,(H,24,26)(H,21,22,23)
    Synonyms
    compound 20;SBP 3264;SBP3264
  10. 4-[5-amino-6-(1-oxo-1,2,3,4-tetrahydroisoquinolin-6-yl)pyrazin-2-yl]-N-cyclopropyl-N-methylbenzene-1-sulfonamide
    CAS: 1396771-17-7 PubChem CID: 70654965 Formula: C23H23N5O3S Molecular Weight: 449.5
    Out of Stock Item #: A669632
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    Technical Identifiers
    IUPAC Name
    4-[5-amino-6-(1-oxo-3,4-dihydro-2H-isoquinolin-6-yl)pyrazin-2-yl]-N-cyclopropyl-N-methylbenzenesulfonamide
    SMILES
    CN(C1CC1)S(=O)(=O)C1=CC=C(C=C1)C1=CN=C(N)C(=N1)C1=CC=C2C(=O)NCCC2=C1
    InChIKey
    IFTJEMBCNXZLST-UHFFFAOYSA-N
    InChI
    1S/C23H23N5O3S/c1-28(17-5-6-17)32(30,31)18-7-2-14(3-8-18)20-13-26-22(24)21(27-20)16-4-9-19-15(12-16)10-11-25-23(19)29/h2-4,7-9,12-13,17H,5-6,10-11H2,1show more
  11. N-benzyl-4-(benzylsulfamoyl)benzamide
    CAS: 313520-94-4 PubChem CID: 4371240
    Out of Stock Item #: N1022054
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    IUPAC Name
    N-benzyl-4-(benzylsulfamoyl)benzamide
    SMILES
    C1=CC=C(C=C1)CNC(=O)C2=CC=C(C=C2)S(=O)(=O)NCC3=CC=CC=C3
    InChIKey
    QDGVJMITKNOVTP-UHFFFAOYSA-N
    InChI
    1S/C21H20N2O3S/c24-21(22-15-17-7-3-1-4-8-17)19-11-13-20(14-12-19)27(25,26)23-16-18-9-5-2-6-10-18/h1-14,23H,15-16H2,(H,22,24)
  12. 4-[3-chloro-4-[(2-pyridyl)methoxy]anilino]-3-cyano-7-ethoxy-6-(N-acetyl amino)quinoline
    CAS: 915941-95-6 EC Number: 810-024-0 Formula: C26H22ClN5O3 Molecular Weight: 487.900
    Out of Stock Item #: C1034307
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    IUPAC Name
    N-[4-[3-chloro-4-(pyridin-2-ylmethoxy)anilino]-3-cyano-7-ethoxyquinolin-6-yl]acetamide
    SMILES
    CCOC1=C(C=C2C(=C1)N=CC(=C2NC3=CC(=C(C=C3)OCC4=CC=CC=N4)Cl)C#N)NC(=O)C
    InChIKey
    YUNSMEPCTRVPTN-UHFFFAOYSA-N
    InChI
    1S/C26H22ClN5O3/c1-3-34-25-12-22-20(11-23(25)31-16(2)33)26(17(13-28)14-30-22)32-18-7-8-24(21(27)10-18)35-15-19-6-4-5-9-29-19/h4-12,14H,3,15H2,1-2H3,(Hshow more
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