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Tyrosine-protein kinase receptor ufo (AXL)

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  1. Foretinib (GSK1363089), Vascular endothelial growth factor receptor inhibitor
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    Foretinib (GSK1363089), Vascular endothelial growth factor receptor inhibitor
    CAS: 849217-64-7 EC Number: 629-893-0 Formula: C34H34F2N4O6 Molecular Weight: 632.65
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: F127011
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    IUPAC Name
    1-N'-[3-fluoro-4-[6-methoxy-7-(3-morpholin-4-ylpropoxy)quinolin-4-yl]oxyphenyl]-1-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
    SMILES
    COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
    InChIKey
    CXQHYVUVSFXTMY-UHFFFAOYSA-N
    InChI
    1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3show more
    Synonyms
    81FH7VK1C4 | Foretinib [USAN:INN] | N-(3-FLUORO-4-((6-METHOXY-7-(3-(MORPHOLIN-4-YL)PROPOXY)QUINOLIN-4-YL)OXY) PHENYL)...
  2. UNC2371(MRX-2843)
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    UNC2371(MRX-2843)
    CAS: 1429882-07-4 PubChem CID: 89495685 Formula: C29H40N6O Molecular Weight: 488.67
    ≥97%
    Out of Stock Item #: U174179
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    IUPAC Name
    4-[2-(2-cyclopropylethylamino)-5-[4-[(4-methylpiperazin-1-yl)methyl]phenyl]pyrrolo[2,3-d]pyrimidin-7-yl]cyclohexan-1-ol
    SMILES
    CN1CCN(CC1)CC2=CC=C(C=C2)C3=CN(C4=NC(=NC=C34)NCCC5CC5)C6CCC(CC6)O
    InChIKey
    LBEJYFVJIPQSNX-UHFFFAOYSA-N
    InChI
    1S/C29H40N6O/c1-33-14-16-34(17-15-33)19-22-4-6-23(7-5-22)27-20-35(24-8-10-25(36)11-9-24)28-26(27)18-31-29(32-28)30-13-12-21-2-3-21/h4-7,18,20-21,24-25show more
    Synonyms
    s6839 | Cyclohexanol, 4-(2-((2-cyclopropylethyl)amino)-5-(4-((4-methyl-1-piperazinyl)methyl)phenyl)-7H-pyrrolo(2,3-d)...
  3. Gilteritinib, Tyrosine-protein kinase receptor UFO inhibitor
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    Gilteritinib, Tyrosine-protein kinase receptor UFO inhibitor
    CAS: 1254053-43-4 EC Number: 107-777-6 Formula: C29H44N8O3 Molecular Weight: 552.7115
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
    In Stock Item #: G172979
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    IUPAC Name
    6-ethyl-3-[3-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]anilino]-5-(oxan-4-ylamino)pyrazine-2-carboxamide
    SMILES
    CCC1=C(N=C(C(=N1)C(=O)N)NC2=CC(=C(C=C2)N3CCC(CC3)N4CCN(CC4)C)OC)NC5CCOCC5
    InChIKey
    GYQYAJJFPNQOOW-UHFFFAOYSA-N
    InChI
    1S/C29H44N8O3/c1-4-23-28(31-20-9-17-40-18-10-20)34-29(26(33-23)27(30)38)32-21-5-6-24(25(19-21)39-3)37-11-7-22(8-12-37)36-15-13-35(2)14-16-36/h5-6,19-2show more
    Synonyms
    GILTERITINIB [WHO-DD] | Gilteritinib HCl | NCGC00481652-01 | AS-35199 | GILTERITINIB [MI] | 1,4-Oxadiazole, 2-(o-hydr...
  4. Methyl 7-azaindole-3-carboxylate
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    Methyl 7-azaindole-3-carboxylate
    CAS: 808137-94-2 EC Number: 691-925-4 Formula: C9H8N2O2 Molecular Weight: 176.17
    ≥95%
    In Stock Item #: M139286
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    IUPAC Name
    methyl 1H-pyrrolo[2,3-b]pyridine-3-carboxylate
    SMILES
    COC(=O)C1=CNC2=C1C=CC=N2
    InChIKey
    XYRUNIAHPKBUJT-UHFFFAOYSA-N
    InChI
    1S/C9H8N2O2/c1-13-9(12)7-5-11-8-6(7)3-2-4-10-8/h2-5H,1H3,(H,10,11)
    Synonyms
    CG-0232 | BBL031597 | EN300-69170 | NSC783332 | PB14761 | 1H-Pyrrolo[2,3-b]Pyridine-3-Carboxylic Acid, Methyl Ester |...
  5. Methyl 7-azaindole-2-carboxylate
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    Methyl 7-azaindole-2-carboxylate
    CAS: 394223-02-0 EC Number: 876-548-7 Formula: C9H8N2O2 Molecular Weight: 176.17
    ≥95%
    In Stock Item #: M170101
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    IUPAC Name
    methyl 1H-pyrrolo[2,3-b]pyridine-2-carboxylate
    SMILES
    COC(=O)C1=CC2=C(N1)N=CC=C2
    InChIKey
    HWOQCGSIDCQVRM-UHFFFAOYSA-N
    InChI
    1S/C9H8N2O2/c1-13-9(12)7-5-6-3-2-4-10-8(6)11-7/h2-5H,1H3,(H,10,11)
    Synonyms
    SY005381 | 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester | MFCD08752938 | AMY18759 | EN300-84465 | J-52257...
  6. 7-Azaindole
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    7-Azaindole
    CAS: 271-63-6 EC Number: 205-981-0 Formula: C7H6N2 Molecular Weight: 118.14
    ≥98%
    In Stock Item #: A124841
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    Technical Identifiers
    IUPAC Name
    1H-pyrrolo[2,3-b]pyridine
    SMILES
    C1=CC2=C(NC=C2)N=C1
    InChIKey
    MVXVYAKCVDQRLW-UHFFFAOYSA-N
    InChI
    1S/C7H6N2/c1-2-6-3-5-9-7(6)8-4-1/h1-5H,(H,8,9)
    Synonyms
    NCIOpen2_000707 | CHEBI:194830 | HY-50542 | 1-H-pyrrolo[2,3-b]pyridine | 1H-Pyrrolo[2,3-b]pyridine | AKOS000446848 | ...
  7. BMS-794833, Inhibitor of MER proto-oncogene; tyrosine kinase
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    BMS-794833, Inhibitor of MER proto-oncogene; tyrosine kinase
    CAS: 1174046-72-0 Formula: C23H15ClF2N4O3 Molecular Weight: 468.84
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: B129768
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    IUPAC Name
    N-[4-(2-amino-3-chloropyridin-4-yl)oxy-3-fluorophenyl]-5-(4-fluorophenyl)-4-oxo-1H-pyridine-3-carboxamide
    SMILES
    C1=CC(=CC=C1C2=CNC=C(C2=O)C(=O)NC3=CC(=C(C=C3)OC4=C(C(=NC=C4)N)Cl)F)F
    InChIKey
    PDYXPCKITKHFOZ-UHFFFAOYSA-N
    InChI
    1S/C23H15ClF2N4O3/c24-20-19(7-8-29-22(20)27)33-18-6-5-14(9-17(18)26)30-23(32)16-11-28-10-15(21(16)31)12-1-3-13(25)4-2-12/h1-11H,(H2,27,29)(H,28,31)(H,show more
    Synonyms
    SCHEMBL13770016 | J-690046 | HY-10497 | AC-32814 | BDBM50146164 | BMS 794833 | 1174046-72-0 | SMR004702756 | metatini...
  8. CEP-40783
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    CEP-40783
    CAS: 1437321-24-8 Formula: C31H26F2N4O6 Molecular Weight: 588.6
    ≥98%
    In Stock Item #: C174233
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    IUPAC Name
    N-[4-(6,7-dimethoxyquinolin-4-yl)oxy-3-fluorophenyl]-3-(4-fluorophenyl)-2,4-dioxo-1-propan-2-ylpyrimidine-5-carboxamide
    SMILES
    CC(C)N1C=C(C(=O)N(C1=O)C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C5C=C(C(=CC5=NC=C4)OC)OC)F
    InChIKey
    FKCWHHYUMFGOPY-UHFFFAOYSA-N
    InChI
    1S/C31H26F2N4O6/c1-17(2)36-16-22(30(39)37(31(36)40)20-8-5-18(32)6-9-20)29(38)35-19-7-10-26(23(33)13-19)43-25-11-12-34-24-15-28(42-4)27(41-3)14-21(24)2show more
    Synonyms
    AS-35141 | N-(4-((6,7-dimethoxyquinolin-4-yl)oxy)-3-fluorophenyl)-3-(4-fluorophenyl)-1-isopropyl-2,4-dioxo-1,2,3,4-te...
  9. Ki8751
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    Ki8751
    CAS: 228559-41-9 Formula: C24H18F3N3O4 Molecular Weight: 469.41
    ≥98%
    In Stock Item #: K125876
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    Technical Identifiers
    IUPAC Name
    1-(2,4-difluorophenyl)-3-[4-(6,7-dimethoxyquinolin-4-yl)oxy-2-fluorophenyl]urea
    SMILES
    COC1=CC2=C(C=CN=C2C=C1OC)OC3=CC(=C(C=C3)NC(=O)NC4=C(C=C(C=C4)F)F)F
    InChIKey
    LFKQSJNCVRGFCC-UHFFFAOYSA-N
    InChI
    1S/C24H18F3N3O4/c1-32-22-11-15-20(12-23(22)33-2)28-8-7-21(15)34-14-4-6-19(17(27)10-14)30-24(31)29-18-5-3-13(25)9-16(18)26/h3-12H,1-2H3,(H2,29,30,31)
    Synonyms
    1-(2,4-difluorophenyl)-3-[4-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-fluorophenyl]urea | HMS1787L13 | SB19355 | BRD-K47150...
  10. LY2801653, Hepatocyte growth factor receptor inhibitor
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    LY2801653, Hepatocyte growth factor receptor inhibitor
    CAS: 1206799-15-6 EC Number: 806-589-8 Formula: C30H22F2N6O3 Molecular Weight: 552.53
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: L127298
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    IUPAC Name
    N-[3-fluoro-4-[1-methyl-6-(1H-pyrazol-4-yl)indazol-5-yl]oxyphenyl]-1-(4-fluorophenyl)-6-methyl-2-oxopyridine-3-carboxamide
    SMILES
    CC1=CC=C(C(=O)N1C2=CC=C(C=C2)F)C(=O)NC3=CC(=C(C=C3)OC4=C(C=C5C(=C4)C=NN5C)C6=CNN=C6)F
    InChIKey
    QHADVLVFMKEIIP-UHFFFAOYSA-N
    InChI
    1S/C30H22F2N6O3/c1-17-3-9-23(30(40)38(17)22-7-4-20(31)5-8-22)29(39)36-21-6-10-27(25(32)12-21)41-28-11-18-16-35-37(2)26(18)13-24(28)19-14-33-34-15-19/hshow more
    Synonyms
    2,2'-Dithiobis[benzothiazole] | SCHEMBL2716 | s7014 | NSC800788 | NSC-800788 | CCG-270011 | LY 2801653 | BDBM50172078...
  11. Amuvatinib (MP-470), Platelet-derived growth factor receptor alpha inhibitor
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    Amuvatinib (MP-470), Platelet-derived growth factor receptor alpha inhibitor
    CAS: 850879-09-3 Formula: C23H21N5O3S Molecular Weight: 447.52
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    In Stock Item #: M127412
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    IUPAC Name
    N-(1,3-benzodioxol-5-ylmethyl)-4-([1]benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide
    SMILES
    C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6
    InChIKey
    FOFDIMHVKGYHRU-UHFFFAOYSA-N
    InChI
    1S/C23H21N5O3S/c32-23(24-12-15-5-6-18-19(11-15)30-14-29-18)28-9-7-27(8-10-28)22-21-20(25-13-26-22)16-3-1-2-4-17(16)31-21/h1-6,11,13H,7-10,12,14H2,(H,2show more
    Synonyms
    N-(benzo[d][1,3]dioxol-5-ylmethyl)-4-(benzofuro[3,2-d]pyrimidin-4-yl)piperazine-1-carbothioamide | NSC754349 | NSC-75...
  12. 5-Methoxy-2-methylindole - ≥98%, CAS No. 1076-74-0 by
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    5-Methoxy-2-methylindole
    CAS: 1076-74-0 EC Number: 214-066-5 Formula: C10H11NO Molecular Weight: 161.2
    Solid ≥98%
    In Stock Item #: M113476
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    Technical Identifiers
    IUPAC Name
    5-methoxy-2-methyl-1H-indole
    SMILES
    CC1=CC2=C(N1)C=CC(=C2)OC
    InChIKey
    VSWGLJOQFUMFOQ-UHFFFAOYSA-N
    InChI
    1S/C10H11NO/c1-7-5-8-6-9(12-2)3-4-10(8)11-7/h3-6,11H,1-2H3
    Synonyms
    SR-01000640461-1 | 1H-Indole, 5-methoxy-2-methyl- | EINECS 214-066-5 | AC-23427 | AS-19488 | NCGC00188230-02 | AKOS00...
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