TGF-beta/Smad - TGF-beta/Smad Supplier | High Purity

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SIS 3 Hydrochloride
CAS: 521984-48-5 PubChem CID: 16079005 Formula: C₂₈H₂₇N₃O₃•HCl Molecular Weight: 489.99

≥98%

● In Stock — US Item #: S276442
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IUPAC Name

(E)-1-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)-3-(1-methyl-2-phenylpyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-one;hydrochloride

SMILES

CN1C(=C(C2=C1N=CC=C2)C=CC(=O)N3CCC4=CC(=C(C=C4C3)OC)OC)C5=CC=CC=C5.Cl

InChIKey
CDKIEBFIMCSCBB-CALJPSDSSA-N

InChI

1S/C28H27N3O3.ClH/c1-30-27(19-8-5-4-6-9-19)22(23-10-7-14-29-28(23)30)11-12-26(32)31-15-13-20-16-24(33-2)25(34-3)17-21(20)18-31;/h4-12,14,16-17H,13,15,show more

Synonyms
(E)-1-[6,7-Dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl]-3-(1-methyl-2-phenyl-1H-pyrrolo[2,3-b]pyridin-3-yl)prop-2-en-1-...
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Pirfenidone
CAS: 53179-13-8 EC Number: 621-260-7 Formula: C₁₂H₁₁NO Molecular Weight: 185.22

Solid Moligand™ ? ≥98%(GC)

● In Stock — US Item #: P129335
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IUPAC Name

5-methyl-1-phenylpyridin-2-one

SMILES

CC1=CN(C(=O)C=C1)C2=CC=CC=C2

InChIKey
ISWRGOKTTBVCFA-UHFFFAOYSA-N

InChI

1S/C12H11NO/c1-10-7-8-12(14)13(9-10)11-5-3-2-4-6-11/h2-9H,1H3

Synonyms
MFCD00866047 | Pirfenidona [INN-Spanish] | PIRFENIDONE [INN] | Pirfenidone(AMR69) | 5-Methyl-1-phenyl-2(1H)-pyridone ...
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Trimethylamine N-Oxide(TMANO)
CAS: 1184-78-7 EC Number: 214-675-6 PubChem CID: 1145 Formula: C₃H₉NO Molecular Weight: 75.11

Solid Moligand™ ? ≥95%(T)

● In Stock — US Item #: T162064
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IUPAC Name

N,N-dimethylmethanamine oxide

SMILES

C[N+](C)(C)[O-]

InChIKey
UYPYRKYUKCHHIB-UHFFFAOYSA-N

InChI

1S/C3H9NO/c1-4(2,3)5/h1-3H3

Synonyms
Trimethylamine oxide | NSC 408426 | MFCD00002048 | Trimethlamine-N-oxide | Triox | CHEBI:15724 | EN300-396337 | Trime...
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Neohesperidin
CAS: 13241-33-3 EC Number: 236-216-9 Formula: C₂₈H₃₄O₁₅ Molecular Weight: 610.56

Solid Analytical standard ? Moligand™ ? ≥97%

● In Stock — US Item #: N101968
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IUPAC Name

(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxshow more

SMILES

CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O

InChIKey
ARGKVCXINMKCAZ-UZRWAPQLSA-N

InChI

1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/hshow more

Synonyms
(S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-...
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Trimethylamine-d9 N-Oxide
CAS: 1161070-49-0 PubChem CID: 71752814 Formula: C₃D₉NO Molecular Weight: 84.17

≥98 atom% D,≥98%

● In Stock — US Item #: T336882
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IUPAC Name

1,1,1-trideuterio-N,N-bis(trideuteriomethyl)methanamine oxide

SMILES

C[N+](C)(C)[O-]

InChIKey
UYPYRKYUKCHHIB-GQALSZNTSA-N

InChI

1S/C3H9NO/c1-4(2,3)5/h1-3H3/i1D3,2D3,3D3

Synonyms
Trimethylamine N-oxide-d9 | Trimethylamine-d9 N-Oxide, 98 atom % D, 98% (CP) | 1,1,1-trideuterio-N,N-bis(trideuteriom...
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Asiaticoside
CAS: 16830-15-2 EC Number: 240-851-7 Formula: C₄₈H₇₈O₁₉ Molecular Weight: 959.12

Solid Analytical standard ? Moligand™ ? ≥98%

● In Stock — US Item #: A111276
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IUPAC Name

[(2S,3R,4S,5S,6R)-6-[[(2R,3R,4R,5S,6R)-3,4-dihydroxy-6-(hydroxymethyl)-5-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxymethyl]-show more

SMILES

CC1CCC2(CCC3(C(=CCC4C3(CCC5C4(CC(C(C5(C)CO)O)O)C)C)C2C1C)C)C(=O)OC6C(C(C(C(O6)COC7C(C(C(C(O7)CO)OC8C(C(C(C(O8)C)O)O)O)O)O)O)O)O

InChIKey
WYQVAPGDARQUBT-FGWHUCSPSA-N

InChI

1S/C48H78O19/c1-20-10-13-48(15-14-46(6)23(29(48)21(20)2)8-9-28-44(4)16-24(51)39(60)45(5,19-50)27(44)11-12-47(28,46)7)43(61)67-42-36(58)33(55)31(53)26(show more

Synonyms
(-)-SENECIONINE | NSC-36002 | (2alpha,3beta,4alpha)-2,3,23-TRIHYDROXYURS-12-EN-28-OIC ACID O-6-DEOXY-alpha-L-MANNOPYR...
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Ammothamnine
CAS: 16837-52-8 EC Number: 605-514-4 Formula: C₁₅H₂₄N₂O₂ Molecular Weight: 264.36

≥98%(HPLC)

● In Stock — US Item #: A111286
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IUPAC Name

(1R,2R,9S,17S)-13-oxido-7-aza-13-azoniatetracyclo[7.7.1.02,7.013,17]heptadecan-6-one

SMILES

C1CC2C3CCC[N+]4(C3C(CCC4)CN2C(=O)C1)[O-]

InChIKey
XVPBINOPNYFXID-LHDUFFHYSA-N

InChI

1S/C15H24N2O2/c18-14-7-1-6-13-12-5-3-9-17(19)8-2-4-11(15(12)17)10-16(13)14/h11-13,15H,1-10H2/t11-,12+,13+,15-,17?/m0/s1

Synonyms
Pachycarpidine | BDBM50597716 | Oxymatrine | BBL030371 | MLS001215101 | rel-(41S,7aS,13aR,13bR)-10-Oxohexadecahydrodi...
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Alantolactone
CAS: 546-43-0 Formula: C₁₅H₂₀O₂ Molecular Weight: 232.32

Analytical standard ? ≥97%(HPLC)

● In Stock — US Item #: A114070
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Technical Identifiers

IUPAC Name

(3aR,5S,8aR,9aR)-5,8a-dimethyl-3-methylidene-5,6,7,8,9,9a-hexahydro-3aH-benzo[f][1]benzofuran-2-one

SMILES

CC1CCCC2(C1=CC3C(C2)OC(=O)C3=C)C

InChIKey
PXOYOCNNSUAQNS-AGNJHWRGSA-N

InChI

1S/C15H20O2/c1-9-5-4-6-15(3)8-13-11(7-12(9)15)10(2)14(16)17-13/h7,9,11,13H,2,4-6,8H2,1,3H3/t9-,11+,13+,15+/m0/s1

Synonyms
(3aR,5S,8aR,9aR)-5,8a-Dimethyl-3-methylene-3,3a,6,7,8,8a,9,9a-octahydronaphtho[2,3-b]furan-2(5H)-one | Q21099633 | DT...
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Halofuginone hydrobromide
CAS: 64924-67-0 Formula: C₁₆H₁₇BrClN₃O₃•HBr Molecular Weight: 495.59

≥98%(HPLC)

● In Stock — US Item #: H288889
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Technical Identifiers

IUPAC Name

7-bromo-6-chloro-3-[3-[(2S,3R)-3-hydroxypiperidin-2-yl]-2-oxopropyl]quinazolin-4-one;hydrobromide

SMILES

C1CC(C(NC1)CC(=O)CN2C=NC3=CC(=C(C=C3C2=O)Cl)Br)O.Br

InChIKey
SJUWEPZBTXEUMU-LDXVYITESA-N

InChI

1S/C16H17BrClN3O3.BrH/c17-11-6-13-10(5-12(11)18)16(24)21(8-20-13)7-9(22)4-14-15(23)2-1-3-19-14;/h5-6,8,14-15,19,23H,1-4,7H2;1H/t14-,15+;/m0./s1

Synonyms
MFCD00017259 | RU-19110 (hydrobromide) | Halofuginone hydrobromide, (-)- | AMY26820 | HY-N1584A | AKOS015920268 | Hal...
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Kartogenin
CAS: 4727-31-5 Formula: C₂₀H₁₅NO₃ Molecular Weight: 317.34

Solid Moligand™ ? ≥98%(HPLC)

● In Stock — US Item #: K134657
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IUPAC Name

2-[(4-phenylphenyl)carbamoyl]benzoic acid

SMILES

C1=CC=C(C=C1)C2=CC=C(C=C2)NC(=O)C3=CC=CC=C3C(=O)O

InChIKey
SLUINPGXGFUMLL-UHFFFAOYSA-N

InChI

1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)

Synonyms
KGN | 2-[[1,1'-Biphenyl]-4-ylcarbamoyl]benzoic Acid | 2-[(Biphenyl-4-yl)carbamoyl]benzoic acid | 4'-Phenyl-phthalanil...
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R 268712
CAS: 879487-87-3 PubChem CID: 11703284 Formula: C₂₀H₁₈FN₅O Molecular Weight: 363.39

≥98%(HPLC)

● In Stock — US Item #: R286557
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IUPAC Name

2-[4-[2-fluoro-5-[5-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl]phenyl]pyrazol-1-yl]ethanol

SMILES

CC1=NC(=CC=C1)C2=C(C=NN2)C3=CC(=C(C=C3)F)C4=CN(N=C4)CCO

InChIKey
JQGOCCALXFSRHZ-UHFFFAOYSA-N

InChI

1S/C20H18FN5O/c1-13-3-2-4-19(24-13)20-17(11-22-25-20)14-5-6-18(21)16(9-14)15-10-23-26(12-15)7-8-27/h2-6,9-12,27H,7-8H2,1H3,(H,22,25)

Synonyms
SCHEMBL5198271 | C20H18FN5O | NCGC00387472-01 | 4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-py...
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Neohesperidin
CAS: 13241-33-3 EC Number: 236-216-9 Formula: C₂₈H₃₄O₁₅ Molecular Weight: 610.56

Solid Moligand™ ? ≥97%

● In Stock — US Item #: N140716
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Technical Identifiers

IUPAC Name

(2S)-7-[(2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-[(2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-2-yl]oxy-5-hydroxy-2-(3-hydroxshow more

SMILES

CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC(=C(C=C5)OC)O)O)CO)O)O)O)O)O

InChIKey
ARGKVCXINMKCAZ-UZRWAPQLSA-N

InChI

1S/C28H34O15/c1-10-21(33)23(35)25(37)27(39-10)43-26-24(36)22(34)19(9-29)42-28(26)40-12-6-14(31)20-15(32)8-17(41-18(20)7-12)11-3-4-16(38-2)13(30)5-11/hshow more

Synonyms
(S)-7-(((2S,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-3-(((2S,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-...

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Frequently Asked Questions

Which compounds are listed for TGF-beta/Smad?

Compounds associated with TGF-beta/Smad are grouped here under the TGF-beta/Smad classification, with mechanism, structure, and reported potency shown per entry. Use it as a starting shortlist rather than a final selection.

How does TGF-beta/Smad sit within TGF-beta/Smad?

TGF-beta/Smad is one target listing within the TGF-beta/Smad classification. Compounds here may also appear under related targets, so check the selectivity data rather than assuming the annotation is exclusive.

What data should I check before ordering a compound from TGF-beta/Smad?

For compounds listed under TGF-beta/Smad, check purity — typically 98% or better by HPLC — the reported potency and the assay it was measured in, solubility and recommended stock solvent, and storage and stability. Batch-specific values are given on the Certificate of Analysis. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.

How do I find related targets or backup compounds for TGF-beta/Smad?

Browse the parent TGF-beta/Smad listing to reach targets neighbouring TGF-beta/Smad, and use the structure search to find analogs of a compound that worked. Unlisted compounds and bulk quantities: [email protected]. We supply verified businesses, research institutions, universities, and government agencies.