Medronic acid - Moligand™, 10 mM in DMSO , CAS No.1984-15-2

CAS: 1984-15-2 Cat. No.: M1494083 Molecular Weight: 176.00 Beilstein Registry Number: 1(4)3071 EC Number: 217-851-0

GRADE & PURITY Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Medronic acid (Methylenediphosphonic acid) is a methylene-substituted bisphosphonate. Medronic acid has an affinity for the surface of hydroxyapatite crystals in the bone matrix and adheres to them. Medronic acid can be used in complex with radioisotopes in bone imaging. Due to its strong metal chelating ability, medronic acid is also used as a water treatment chemical. In addition, medronic acid is used as a solvent additive to improve peak shape and signal of metal-sensitive metabolites in LC/MS analysis .

Specifications

Specifications & Purity

Moligand™, 10 mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Names and Identifiers

• Isomeric SMILES: C(P(=O)(O)O)P(=O)(O)O
• WGK Germany: 3
• RTECS: SZ9138000
• Molecular Weight: 176.00
• Beilstein: 1(4)3071
• Reaxy-Rn: 1708494
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1708494&ln=

Chemical and Physical Properties

• Melt Point(°C): 204 °C

References

1. Jiangbin Han, Lijuan Zhai, Jie Wang, Biying Dai, Huiyue Lu, Jiao Chen, Xiaoli Wang, Yuyu Wu, Wen Qian.  (2025)  Mechanism-based perspective on metal ion-induced signal instability and development of a robust LC-MS/MS method for trace quantification of hetrombopag in plasma.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:40639095] [10.1016/j.jpba.2025.117049]