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· · COA & SDS available for every product · Same-day shipping on in-stock items N,N'-Dibenzylquinazoline-2,4-diamine - 10mM in DMSO , CAS No.177355-84-9
GRADE & PURITY 10mM in DMSO
Synonyms
DBeQ|177355-84-9|N2,N4-dibenzylquinazoline-2,4-diamine|N,N'-dibenzylquinazoline-2,4-diamine|2-N,4-N-dibenzylquinazoline-2,4-diamine|KUC105555N|MLS000769571|SMR002239188|SMR000434303|N*2*,N*4*-Dibenzyl-quinazoline-2,4-diamine|JRF 12|2,4-Quinazolinediamine,
Shipped In
Dry ice packs + Cold packs
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Why this grade 10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview The product can be stored for up to 12 months.
Application
HeLa cells were treated with DBeQ and the effects on in vivo ubiquitination and protein dislocation were studied by live cell imaging.
Specifications Synonyms
DBeQ | 177355-84-9 | N2, N4-dibenzylquinazoline-2, 4-diamine | N, N'-dibenzylquinazoline-2, 4-diamine | 2-N, 4-N-dibenzylquinazoline-2, 4-diamine | KUC105555N | MLS000769571 | SMR002239188 | SMR000434303 | N*2*, N*4*-Dibenzyl-quinazoline-2, 4-diamine | JRF 12 | 2, 4-Quinazolinediamine,
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Selective, potent, reversible and ATP-competitive p97 ATPase inhibitor (IC 50 = 1.5 μM). Inhibits a number of cellular processes including ER-associated degradation, ubiquitin fusion degradation and autophagosome maturation.
DBeQ is a potent and specific
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Canonical Smiles C1=CC=C(C=C1)CNC2=NC(=NC3=CC=CC=C32)NCC4=CC=CC=C4 IUPAC Name 2-N,4-N-dibenzylquinazoline-2,4-diamine InChIKey QAIMUUJJAJBPCL-UHFFFAOYSA-N INCHI 1S/C22H20N4/c1-3-9-17(10-4-1)15-23-21-19-13-7-8-14-20(19)25-22(26-21)24-16-18-11-5-2-6-12-18/h1-14H,15-16H2,(H2,23,24,25,26) Isomeric SMILES C1=CC=C(C=C1)CNC2=NC(=NC3=CC=CC=C32)NCC4=CC=CC=C4 Molecular Weight 340.42 Reaxy-Rn 7440169 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7440169&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Diazanaphthalenes Subclass Benzodiazines Intermediate Tree Nodes Quinazolines Direct Parent Quinazolinamines Alternative Parents Benzylamines Secondary alkylarylamines Aminopyrimidines and derivatives Imidolactams Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Quinazolinamine - Benzylamine - Aminopyrimidine - Secondary aliphatic/aromatic amine - Imidolactam - Benzenoid - Pyrimidine - Monocyclic benzene moiety - Heteroaromatic compound - Azacycle - Secondary amine - Amine - Organopnictogen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound Description This compound belongs to the class of organic compounds known as quinazolinamines. These are heterocyclic aromatic compounds containing a quianazoline moiety substituted by one or more amine groups. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Sensitivity Heat Sensitive Melt Point(°C) 147.0 to 151.0 °C Molecular Weight 340.400 g/mol XLogP3 5.300 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 6 Exact Mass 340.169 Da Monoisotopic Mass 340.169 Da Topological Polar Surface Area 49.800 Ų Heavy Atom Count 26 Formal Charge 0 Complexity 403.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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