Paroxetine maleate - ≥97% , CAS No.64006-44-6

CAS: 64006-44-6 Cat. No.: P287341 Molecular Weight: 445.44 EC Number: 636-343-3 PubChem CID: 6435921
AVAILABLE TO ORDER
GRADE & PURITY ≥97%
Synonyms
MLS002667577 | NC00077 | Paroxetine maleate salt, >=98% (HPLC), solid | SCHEMBL140608 | (3S,4R)-3-((1,3-BENZODIOXOL-5-YLOXY)METHYL)-4-(4-FLUOROPHENYL)-PIPERIDINE MALEATE | Paroxetine maleate salt | REGID_for_CID_6435921 | (3S,4R)-3-[(1,3-benzodioxol-5-ylo
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
5mg
P287341-5mg
3
$195.90
10mg
P287341-10mg
2
$299.90
25mg
P287341-25mg
1
$617.90
50mg
P287341-50mg
1
$997.90
100mg
P287341-100mg
1
$1,594.90
Enter a quantity for the sizes you want to add.
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Why this grade

≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
MLS002667577 | NC00077 | Paroxetine maleate salt, >=98% (HPLC), solid | SCHEMBL140608 | (3S, 4R)-3-((1, 3-BENZODIOXOL-5-YLOXY)METHYL)-4-(4-FLUOROPHENYL)-PIPERIDINE MALEATE | Paroxetine maleate salt | REGID_for_CID_6435921 | (3S, 4R)-3-[(1, 3-benzodioxol-5-ylo
Specifications & Purity
≥97%
Biochemical and Physiological Mechanisms
Highly potent and selective 5-HT uptake inhibitor that binds with high affinity to the serotonin transporter (Ki= 0.05 nM). Kivalues are 1.1, 350 and 1100 nM for inhibition of [3H]-5-HT, [3H]-l-NA and [3H]-DA uptake respectively. Displays minimal affinity
Storage
Store at 2-8°C
Shipped In
Wet ice
This product requires cold chain shipping. Ground and other economy services are not available.
Purity
≥97%
Names and Identifiers
Pubchem Sid488195778
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/488195778
Canonical SmilesC1CNCC(C1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.C(=CC(=O)O)C(=O)O
IUPAC Name(3S,4R)-3-(1,3-benzodioxol-5-yloxymethyl)-4-(4-fluorophenyl)piperidine;(Z)-but-2-enedioic acid
InChIKeyAEIUZSKXSWGSRU-QXGDPHCHSA-N
INCHI1S/C19H20FNO3.C4H4O4/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;5-3(6)1-2-4(7)8/h1-6,9,14,17,21H,7-8,10-12H2;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,17-;/m0./s1
Isomeric SMILES C1CNC[C@H]([C@@H]1C2=CC=C(C=C2)F)COC3=CC4=C(C=C3)OCO4.C(=C\C(=O)O)\C(=O)O
WGK Germany 3
RTECS TM4569300
PubChem CID 6435921
Molecular Weight 445.44

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClassPiperidines
SubclassPhenylpiperidines
Intermediate Tree Nodes Not available
Direct ParentPhenylpiperidines
Alternative Parents Benzodioxoles  Alkyl aryl ethers  Aralkylamines  Fluorobenzenes  Unsaturated fatty acids  Aryl fluorides  Dicarboxylic acids and derivatives  Acetals  Oxacyclic compounds  Azacyclic compounds  Carboxylic acids  Dialkylamines  Organic oxides  Carbonyl compounds  Organofluorides  Organopnictogen compounds  Hydrocarbon derivatives  
Molecular FrameworkNot available
Substituents Phenylpiperidine - Benzodioxole - Alkyl aryl ether - Fluorobenzene - Halobenzene - Aralkylamine - Dicarboxylic acid or derivatives - Aryl fluoride - Aryl halide - Monocyclic benzene moiety - Fatty acyl - Fatty acid - Benzenoid - Unsaturated fatty acid - Secondary amine - Carboxylic acid derivative - Carboxylic acid - Secondary aliphatic amine - Azacycle - Oxacycle - Ether - Acetal - Organic nitrogen compound - Organohalogen compound - Organofluoride - Organonitrogen compound - Carbonyl group - Organooxygen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Amine - Organic oxygen compound - Aromatic heteropolycyclic compound
DescriptionThis compound belongs to the class of organic compounds known as phenylpiperidines. These are compounds containing a phenylpiperidine skeleton, which consists of a piperidine bound to a phenyl group.
External Descriptors maleate salt
3D Structure
Interactive Chemical Structure Model





Associated Targets(Human)
GLP1R Tclin Glucagon-like peptide 1 receptor (111429 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HepG2 (196354 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KDM4A Tchem Lysine-specific demethylase 4A (52245 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SMAD3 Tchem Mothers against decapentaplegic homolog 3 (68039 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GMNN Tbio Geminin (128009 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
microRNA 21 (64692 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BAZ2B Tchem Bromodomain adjacent to zinc finger domain protein 2B (56204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATXN2 Tbio Ataxin-2 (54410 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic (40980 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Associated Targets(non-human)
Pseudomonas aeruginosa (123386 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Klebsiella pneumoniae (43867 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Acinetobacter baumannii (41033 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Escherichia coli (133304 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Cryptococcus neoformans (21258 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

10 results found

Lot NumberCertificate TypeDateItem
C2317032Certificate of AnalysisJan 26, 2026 P287341
C2317030Certificate of AnalysisJan 19, 2026 P287341
C23161526Certificate of AnalysisJan 07, 2026 P287341
C23161507Certificate of AnalysisJan 07, 2026 P287341
C23161455Certificate of AnalysisJan 07, 2026 P287341
C23161459Certificate of AnalysisDec 10, 2025 P287341
C23161484Certificate of AnalysisDec 10, 2025 P287341
C23161494Certificate of AnalysisDec 10, 2025 P287341
C23161500Certificate of AnalysisDec 10, 2025 P287341
C23161509Certificate of AnalysisDec 10, 2025 P287341
Chemical and Physical Properties
SolubilitySolvent:ethanol, Max Conc. mg/mL: 44.54, Max Conc. mM: 100; Solvent:DMSO, Max Conc. mg/mL: 44.54, Max Conc. mM: 100
Molecular Weight445.400 g/mol
XLogP3
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass445.154 Da
Monoisotopic Mass445.154 Da
Topological Polar Surface Area114.000 Ų
Heavy Atom Count32
Formal Charge0
Complexity521.000
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count2
Solution Calculators
Reviews

Customer Reviews

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