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Poly (I:C):Kanamycin (1:1) (sodium) , CAS No.P658921
AVAILABLE TO ORDER
Storage
Protected from light,Store at -20°C,Desiccated
Shipped In
Ice chest + Ice pads
224,000+ research products · Triple ISO certified · COA & SDS available for every product · Same-day shipping on in-stock items
Why this grade
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Protected from light,Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Overview
Poly (I:C):Kanamycin (1:1) sodium is an isometric complex of Poly (I:C) ( HY-135748 ) and Kanamycin ( HY-16566 ). Poly(I:C) sodium, a synthetic analog of double-stranded RNA, is a TLR3 and retinoic acid-inducible gene I receptor ( RIG-I and b>MDA5 ) agoni
Appearance:Solid
IC50& Target:TLR3 , RIG-I , MDA5 , apoptosis
In Vitro:Poly (I:C) sodium (20 ng/mL; 24 hours; WM793, WM278, WM239A, WM9 and 1205Lu cells) treatment strongly reduces viability from 100% in controls to 20%–50% within 24 hours. Poly (I:C) sodium (200 ng/mL; 24 hours; 1205Lu cells) treatment induces apoptosi
In Vivo:Poly (I:C) sodium treatment inhibits tumor growth in NOD/SCID immunodeficient mice injected with 1205Lu cells. The level of human DNA is 50% lower in mice treated with Poly (I:C) sodium. Kanamycin (2, 4mg/kg; s.c.; once daily, 6 times a week for 3 w
Biological Activity:Poly (I:C):Kanamycin (1:1) sodium is an isometric complex of Poly (I:C) ( HY-135748 ) and Kanamycin ( HY-16566 ). Poly(I:C) sodium, a synthetic analog of double-stranded RNA, is a TLR3 and retinoic acid-inducible gene I receptor ( RIG-I and b>MDA5 ) agoni
Specifications
Storage
Protected from light, Store at -20°C, Desiccated
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Action Type
AGONIST
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificates（CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 F2511003 | Certificate of Analysis | Jun 20, 2025 | P658921 |
Chemical and Physical Properties
| Sensitivity | Moisture sensitive |
|---|
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