Recombinant Human B7-H2 Protein, >95%(SDS-PAGE)

Cat. No.: rp147187
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Bioactive ? Bioactive grade — verified to retain biological activity in functional assays. Use when the molecule must be functionally active, not just pure. ActiBioPure™ ? ActiBioPure™ — Aladdin's premier line for bioactive and recombinant products. Use when both high purity and preserved biological activity are required. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. His Tag ? His tag grade — recombinant protein bearing a His tag for affinity purification/detection. Use to purify, immobilize, or detect the tagged protein. ≥95%(SDS-PAGE)
Expression System
HEK293
Accession #
O75144
Protein Tag
C-His
Expression system
HEK293
Endotoxin Concentration
<0.01 EU/μg
Bioactivity
Immobilized Human ICOSLG at 1 μg/mL (100 μL/well) can bind Human ICOS/CD278 with a linear range of 2-15 ng/mL.
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
20μg
rp147187-20μg
≥10
$105.90
100μg
rp147187-100μg
2
$395.90
1mg
rp147187-1mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$2,279.90
200μg
rp147187-200μg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$513.90
Enter a quantity for the sizes you want to add.
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Why this grade

Animal Free,Carrier Free,Bioactive,ActiBioPure™,Azide Free,His-Tag,≥95%(SDS-PAGE) ActiBioPure™,Animal Free,Azide Free,Bioactive,Carrier Free,His Tag for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Purity

>95% SDS-PAGE.


Function

Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.


Specifications

Product Name
Recombinant Human B7-H2 Protein, >95%(SDS-PAGE)
Synonyms
B7H2 | B7-H2 | B7H2B7 homolog 2 | B7-H2B7-related protein 1 | B7RP-1 | B7RP1B7-like protein Gl50 | LICOS | CD275 antigen | CD275 | GL50 | GL50transmembrane protein B7-H2 ICOS ligand | ICOSL | ICOS-L | ICOSLG | inducible T-cell co-stimulator ligand | KIAA0
Grade
ActiBioPure™, Animal Free, Azide Free, Bioactive, Carrier Free, His Tag
Specifications & Purity
Animal Free, Carrier Free, Bioactive, ActiBioPure™, Azide Free, His-Tag, ≥95%(SDS-PAGE)
Purity
>95%(SDS-PAGE)
Bioactivity
Immobilized Human ICOSLG at 1 μg/mL (100 μL/well) can bind Human ICOS/CD278 with a linear range of 2-15 ng/mL.
Endotoxin Concentration
<0.01 EU/μg
Expression System
HEK293
Species
Human
Amino Acids
19-258 aa
Sequence
DTQEKEVRAMVGSDVELSCACPEGSRFDLNDVYVYWQTSESKTVVTYHIPQNSSLENVDSRYRNRALMSPAGMLRGDFSLRLFNVTPQDEQKFHCLVLSQSLGFQEVLSVEVTLHVAANFSVPVVSAPHSPSQDELTFTCTSINGYPRPNVYWINKTDNSLLDQALQNDTVFLNMRGLYDVVSVLRIARTPSVNIGCCIENVLLQQNLTVGSQTGNDIGERDKITENPVSTGEKNAATWSHHHHHH
Protein Tag
C-His
Accession #
Predicted molecular weight
26 kDa
Molecule Type
Protein
Storage and Shipping
Shape
Lyophilized
Reconstitution
Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at -20~ -80℃ for more than 1 year.
Images

Recombinant Human B7-H2 Protein (rp147187) - Protein Bioactivity
Immobilized Recombinant Human B7-H2 Protein (rp147187) at 1.0 μg/mL can bind Human ICOS/CD278 with a linear range of 2.0 -15.0 ng/mL.

Recombinant Human B7-H2 Protein (rp147187) - SDS-PAGE
3 μg/lane of Recombinant Human B7-H2 was resolved with SDS-PAGE under reducing (R) condition and visualized by Coomassie® Blue staining, showing the band at 43.1 - 55.3 kDa.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

5 results found

Lot NumberCertificate TypeDateItem
ZJ23F1101638Certificate of AnalysisJun 18, 2026 rp147187
ZJ23F1101639Certificate of AnalysisJun 18, 2026 rp147187
ZJ25F1230209Certificate of AnalysisDec 12, 2025 rp147187
ZJ25F1230208Certificate of AnalysisDec 12, 2025 rp147187
ZJ25F1230207Certificate of AnalysisDec 12, 2025 rp147187
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