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SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 34 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Sodium hydrosulfide hydrate is a hydrated inorganic salt of sodium. It participates in the synthesis of (E)-2-cyano-2-(thiazolidin-2-ylidene)ethanethioamide.
| Canonical Smiles | O.[Na+].[SH-] |
|---|---|
| IUPAC Name | sodium;sulfanide;hydrate |
| InChIKey | ZNKXTIAQRUWLRL-UHFFFAOYSA-M |
| INCHI | 1S/Na.H2O.H2S/h;2*1H2/q+1;;/p-1 |
| Isomeric SMILES | O.[Na+].[SH-] |
| PubChem CID | 16211346 |
| UN Number | 2949 |
| Packing Group | II |
| Molecular Weight | 56.06 (anhydrous basis) |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Inorganic compounds |
|---|---|
| Superclass | Mixed metal/non-metal compounds |
| Class | Alkali metal oxoanionic compounds |
| Subclass | Alkali metal hydroxides |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Alkali metal hydroxides |
| Alternative Parents | Inorganic sulfides Inorganic sodium salts Inorganic oxides Inorganic hydrides |
| Molecular Framework | Not available |
| Substituents | Alkali metal hydroxide - Inorganic sodium salt - Inorganic hydride - Inorganic oxide - Inorganic sulfide - Inorganic salt |
| Description | This compound belongs to the class of inorganic compounds known as alkali metal hydroxides. These are inorganic compounds in which the largest oxoanion is hydroxide, and in which the heaviest atom not in an oxoanion is an alkali metal. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
| Certificate of Analysis | Mar 13, 2026 | S106641 | |
| Certificate of Analysis | Mar 13, 2026 | S106641 | |
| Certificate of Analysis | Mar 13, 2026 | S106641 | |
| Certificate of Analysis | Mar 13, 2026 | S106641 | |
| Certificate of Analysis | Mar 13, 2026 | S106641 | |
| Certificate of Analysis | Mar 13, 2026 | S106641 | |
| Certificate of Analysis | Aug 26, 2025 | S106641 | |
| Certificate of Analysis | Aug 26, 2025 | S106641 | |
| Certificate of Analysis | Aug 26, 2025 | S106641 | |
| Certificate of Analysis | Aug 26, 2025 | S106641 | |
| Certificate of Analysis | Aug 26, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Jul 09, 2025 | S106641 | |
| Certificate of Analysis | Mar 25, 2025 | S106641 | |
| Certificate of Analysis | Mar 25, 2025 | S106641 | |
| Certificate of Analysis | Mar 25, 2025 | S106641 | |
| Certificate of Analysis | Mar 25, 2025 | S106641 | |
| Certificate of Analysis | Mar 25, 2025 | S106641 | |
| Certificate of Analysis | Mar 25, 2025 | S106641 | |
| Certificate of Analysis | Mar 25, 2025 | S106641 | |
| Certificate of Analysis | Mar 25, 2025 | S106641 | |
| Certificate of Analysis | Mar 25, 2025 | S106641 | |
| Certificate of Analysis | Apr 23, 2024 | S106641 | |
| Certificate of Analysis | Apr 23, 2024 | S106641 | |
| Certificate of Analysis | Apr 23, 2024 | S106641 | |
| Certificate of Analysis | Apr 23, 2024 | S106641 | |
| Certificate of Analysis | Apr 23, 2024 | S106641 | |
| Certificate of Analysis | Apr 23, 2024 | S106641 | |
| Certificate of Analysis | Apr 23, 2024 | S106641 | |
| Certificate of Analysis | Apr 23, 2024 | S106641 | |
| Certificate of Analysis | Mar 15, 2024 | S106641 | |
| Certificate of Analysis | Mar 15, 2024 | S106641 | |
| Certificate of Analysis | Apr 18, 2023 | S106641 | |
| Certificate of Analysis | Apr 18, 2023 | S106641 | |
| Certificate of Analysis | Apr 18, 2023 | S106641 | |
| Certificate of Analysis | Apr 18, 2023 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Jun 13, 2022 | S106641 | |
| Certificate of Analysis | Feb 10, 2022 | S106641 | |
| Certificate of Analysis | Feb 10, 2022 | S106641 | |
| Certificate of Analysis | Feb 10, 2022 | S106641 | |
| Certificate of Analysis | Feb 10, 2022 | S106641 | |
| Certificate of Analysis | Feb 10, 2022 | S106641 | |
| Certificate of Analysis | Feb 10, 2022 | S106641 |
| Sensitivity | Moisture sensitive. |
|---|---|
| Flash Point(°F) | 194.0 °F |
| Flash Point(°C) | 90 ℃ |
| Melt Point(°C) | 55°C |
| Molecular Weight | 74.080 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 0 |
| Exact Mass | 73.9802 Da |
| Monoisotopic Mass | 73.9802 Da |
| Topological Polar Surface Area | 2.000 Ų |
| Heavy Atom Count | 3 |
| Formal Charge | 0 |
| Complexity | 2.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 3 |
| 1. Xiang Gao, Peng Nie, Peiran Li, Zhi Zheng, Jieshun Cheng, Ying Gu, Yizhong Shen. (2023) Silver metallization-triggered liposome-embedded AIE fluorophore for dual-mode detection of biogenic amines to fight food freshness fraud. FOOD CHEMISTRY, [PMID:37499507] [10.1016/j.foodchem.2023.136961] |
| 2. Weiyuan Ma, Xiuwen Zhang, Le Zhuang. (2023) Exogenous Hydrogen Sulfide Induces A375 Melanoma Cell Apoptosis Through Overactivation of the Unfolded Protein Response. Clinical Cosmetic and Investigational Dermatology, [PMID:37396710] [10.2147/CCID.S412588] |
| 3. Mei Zhang, Yizhong Yuan, Jie Jin, Jinyu Sun, Xiaohui Tian. (2023) Polyvinyl alcohol composite hydrogels/epoxidized natural rubber composites (CMCS/PVA/CS-ENR) with core-shell structure as biomass coating material for slow-release nitrogen fertilizer. PROGRESS IN ORGANIC COATINGS, [PMID:] [10.1016/j.porgcoat.2023.107744] |
| 4. Fan Zhao, Liying Liang, Heng Wang, Chen Wang, Dan Su, Yao Ying, Wangchang Li, Juan Li, Jingwu Zheng, Liang Qiao, Xiaozhou Mou, Shenglei Che, Jing Yu. (2023) H2S-Activated Ion-Interference Therapy: A Novel Tumor Targeted Therapy Based on Copper-Overload-Mediated Cuproptosis and Pyroptosis. ADVANCED FUNCTIONAL MATERIALS, [PMID:] [10.1002/adfm.202300941] |
| 5. Lijuan Chen, Changchang Chen, Yehan Yan, Linlin Yang, Renyong Liu, Jiajia Zhang, Xin Zhang, Chenggen Xie. (2023) Folic Acid Adjustive Polydopamine Organic Nanoparticles Based Fluorescent Probe for the Selective Detection of Mercury Ions. Polymers, 15 (8): (1892). [PMID:37112040] [10.3390/polym15081892] |
| 6. Zhi-Peng Zhu, Jian-Xiang Yu, Xuan-Huan Qiao, Zhi-Fang Yu, Ai-Sheng Xiong, Miao Sun. (2023) Hydrogen sulfide delays yellowing and softening, inhibits nutrient loss in postharvest celery. SCIENTIA HORTICULTURAE, [PMID:] [10.1016/j.scienta.2023.111991] |
| 7. Yan Zhu, Yuanyuan Yao, Jinfeng Xi, Caiguo Tang, Lifang Wu. (2023) Modelling the effect of pH and H2S on the germination of F. graminearum spores under different temperature conditions. LWT-FOOD SCIENCE AND TECHNOLOGY, [PMID:] [10.1016/j.lwt.2023.114530] |
| 8. Xianfeng Wang, Shasha Liu, Jun Zhou, Suyi Zhang, Changjun Hou, Danqun Huo. (2022) Colorimetric detection of Cu2+ based on the inhibition strategy for etching reaction of AgNCs. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:36527967] [10.1016/j.saa.2022.122229] |
| 9. Hui Liu, Mengya Li, Keyong Tang, Jie Liu, Xiumin Li, Xueping Meng. (2022) Evolution of conformation and thermal properties of bovine hides collagen in the sodium sulphide solution. JOURNAL OF MOLECULAR LIQUIDS, [PMID:] [10.1016/j.molliq.2022.120449] |
| 10. Xinrong Liao, Guoqiang Yu, Ruiqing Luo, Qiang Wang, Chiyang He, Shaorong Liu. (2021) Thiol/methylthio-functionalized porous aromatic frameworks for simultaneous capture of aromatic pollutants and Hg(II) from water. JOURNAL OF HAZARDOUS MATERIALS, [PMID:34098263] [10.1016/j.jhazmat.2021.126244] |
| 11. Xiao Xiao, Tingting Wu, Jinxuan Cao, Chunlei Zhu, Yuan Liu, Xin Zhang, Yizhong Shen. (2020) Rational engineering of chromic material as near-infrared ratiometric fluorescent nanosensor for H2S monitoring in real food samples. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2020.128707] |
| 12. Jianqiang Guo, Weimiao Wang, Yue Li, Jiafeng Liang, Qiaosi Zhu, Jiongli Li, Xudong Wang. (2020) Room-temperature synthesis of water-dispersible sulfur-doped reduced graphene oxide without stabilizers. RSC Advances, 10 (44): (26460-26466). [PMID:35519750] [10.1039/D0RA04838K] |
| 13. Lixia Liu, Xuefang Shang, Ruiqi He, Jie Li, Yanmei Chen, Hongli Chen, Tianyun Wang. (2019) Anion binding ability and cytotoxicity of a selective colorimetric chemosensor for H2S based on Zn(Ⅱ) complex. INORGANICA CHIMICA ACTA, [PMID:] [10.1016/j.ica.2019.118994] |
| 14. Jincheng Cheng, Yifan Li, Li Li, Pengpeng Lu, Qiang Wang, Chiyang He. (2019) Thiol-/thioether-functionalized porous organic polymers for simultaneous removal of mercury(II) ion and aromatic pollutants in water. NEW JOURNAL OF CHEMISTRY, 43 (20): (7683-7693). [PMID:] [10.1039/C9NJ01111K] |
| 15. Xuefang Shang, Xuejing Yue, Yanmei Chen, Congshu Li, Hongli Chen, Tianyun Wang. (2018) Design, synthesis, crystal structure and cytotoxicity studies of colorimetric fluorescent “OFF-ON” probes for rapid detection of hydrogen sulfide based on Cu(II) complex. INORGANIC CHEMISTRY COMMUNICATIONS, [PMID:] [10.1016/j.inoche.2018.10.030] |
| 16. Yanmei Chen, Xuefang Shang, Xing Zhao, Jie Li, Jianmei Yuan, Hongli Chen, Jinlian Zhang, Tianyun Wang. (2018) Highly selective probes of copper(II) complexes for sulfide detection and cytotoxicity assay. Journal of Sulfur Chemistry, [PMID:] [10.1080/17415993.2018.1425410] |
| 17. Kui Ren, Xuefang Shang, Jiajia Fu, Peipei Zhao, Jinlian Zhang. (2015) Copper complex based on 2-(phenylimino-methyl)-phenol as a high selective fluoresencent probe for hydrogen sulfide. POLYHEDRON, [PMID:] [10.1016/j.poly.2015.11.022] |
| 18. Jia-Rui Xu, Yi Zheng, Tian-Zhen Liu, Bao-Xiang Zhao, Kai-Ming Wang. (2024) A turn-on fluorescent probe for the detection of hydrogen sulfide and thiophenol in water and beer samples. JOURNAL OF FOOD COMPOSITION AND ANALYSIS, [PMID:] [10.1016/j.jfca.2024.106038] |
| 19. Jie Zhou, Xin Zheng, Chen Xi, Xinyi Tang, Yinjie Jiang, Minjuan Xie, Xiaoyi Fu. (2024) Cr(VI) induced hepatocyte apoptosis through the CTH/H2S/Drp1 signaling pathway. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:39117219] [10.1016/j.scitotenv.2024.175332] |
| 20. Yan Zhu, Yameng Gao, Wenke Wang, Wenjie Kan, Caiguo Tang, Lifang Wu. (2024) Growth boundary of Fusarium graminearum spores as a function of temperature, pH, and H2S based on neural network. Food Bioscience, [PMID:] [10.1016/j.fbio.2024.104797] |
| 21. Miao Sun, Huan-Xuan Qiao, Tao Yang, Peng Zhao, Jun-Hao Zhao, Jia-Ming Luo, Hai-Ye Luan, Xiang Li, Sheng-Cai Wu, Ai-Sheng Xiong. (2024) Hydrogen sulfide alleviates cadmium stress in germinating carrot seeds by promoting the accumulation of proline. JOURNAL OF PLANT PHYSIOLOGY, [PMID:39316927] [10.1016/j.jplph.2024.154357] |
| 22. Xin Zheng, Xinyi Tang, Yinan Xu, Haiyan Zhu, Lianwei Zhong, Chen Chen, Jiajun Cui, Jie Zhou. (2025) Sodium aescinate induces hepatotoxicity through apoptosis and ferroptosis by inhibiting the Nrf2/CTH pathway. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:40064321] [10.1016/j.jep.2025.119608] |
| 23. Daikun Li, Wanying Deng, Yongmin Wang, Yu Tian, Dingyong Wang. (2024) Thiolated non-conjugated nano polymer network for advanced mercury removal from water. JOURNAL OF HAZARDOUS MATERIALS, [PMID:39667150] [10.1016/j.jhazmat.2024.136817] |
| 24. Ying-Chun Song, Yu-Qi Zhao, Chi-Ming Tang, Pedro Garcia-Caparros, Si-Yu Yang, Jia-Qi Yu, Xiu-Ting Hu, Kang-Di Hu, Zhuo Han, Hua Zhang, Gai-Fang Yao. (2025) Biaxially oriented polyethylene (BOPE) and exogenous H2S extend strawberry shelf-life by increasing antioxidant activity and inhibiting pigment accumulation. POSTHARVEST BIOLOGY AND TECHNOLOGY, [PMID:] [10.1016/j.postharvbio.2025.113542] |
| 25. Wenhui Zhang, Min Zhao, Leqiang Wang, Jiaqi Wang, Xiaoguang Ge, Junzhi Liu, Bin Chen, Shi Gao, Jingbin Lu. (2025) Dual NIR-II fluorescence and ratiometric photoacoustic imaging-guided metal-phenolic nanosheets for H2S-activatable synergistic therapy. iScience, [PMID:40352725] [10.1016/j.isci.2025.112425] |
| 26. Yu Zhang, Hongbo Lv, Chao Chen, Zixu Li, Zhaoyu Xie, Miaomiao Wu, Zhixu Zhu, Ying Fan, Jing Li, Qiang Gao, Jun Han, Hui Che, Lan Ma. (2025) Hydrogen sulfide modulates the miR-27a/SLC7A11 axis to inhibit ferroptosis and reduce neuronal damage in ischemic stroke. Journal of Radiation Research and Applied Sciences, [PMID:] [10.1016/j.jrras.2025.102035] |
| 27. Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang. (2025) Thermally Gated Dual-Cascade Nanozyme for Enhanced Mild-Temperature Photothermal Therapy. Advanced Science, [PMID:41203581] [10.1002/advs.202517528] |
| 28. Shui Huaqin, Guo Yanli, Geng Jingbo, Chang Qing, Tian Yuxin, Du Xue, Jin Yan, Li Baoxin, Liu Wei. (2025) Tetrakis(4-pyridylphenyl)ethylene-decorated metal-organic frameworks with aggregation-induced chemiluminescence emission on paper-based platform for volatile sulfur compounds measurement. MICROCHIMICA ACTA, 193 (1): (4). [PMID:41339595] [10.1007/s00604-025-07735-4] |
| 29. Liu Zihao, Huang Yahui, Chen Xiaoming, Zhu Jie, Tang Fanzhou, Zhu Wenkun, Wang Qing, Huang Zhaohui, Zhu Bo. (2026) Promotion of root Cd enrichment and inhibition of its translocation through integrated strategies. PLANT AND SOIL, [PMID:] [10.1007/s11104-025-08241-5] |
| 30. Pan Huang, Kexin Zhang, Ying Chen, Jiaxin Cheng, Shuangshuang Yang, Lin Shi, Yajuan Wang, Qin Zhang. (2026) HHcy promotes hypertension by activating ferroptosis via suppression of the renal H₂S-SLC7A11/GPX4 axis. LIFE SCIENCES, [PMID:41616846] [10.1016/j.lfs.2026.124247] |
| 31. Aikun Liu, Xu Liu, Zixuan Huang, Yanqing Ge. (2026) Nitrogen-Doped Carbon Dots as Fluorescent and Colorimetric Probes for Nitrite Detection. Chemistry-Switzerland, 8 (1): (11). [PMID:] [10.3390/chemistry8010011] |
| 32. Wupei Pan, Xiaoyi Zou, Wenxin Tang, Xin Zheng, Minjuan Xie, Jie Zhou. (2026) Sodium aescinate induces renal cell ferroptosis through the ATF4/CTH/SQOR axis. BIOCHEMICAL PHARMACOLOGY, [PMID:41759595] [10.1016/j.bcp.2026.117847] |
| 33. Shi Yan, Chen Lumiao, Li Mengqi, Wang Jiali, Yin Peiran, Zhou Xun, Cong Qifei, Song Kai. (2026) Hydrogen sulfide ameliorates oxalate crystal-related renal injury via inhibiting the activation of NOD-like receptor thermal protein domain associated protein 3 inflammasome in mice. Urolithiasis, 54 (1): (71). [PMID:] [10.1007/s00240-026-01948-9] |
| 34. Bingyu Ling, Ping Geng, Bowen Fan, Xiaolong Wu, Yi Yang, Jiaheng Lin, Wenjie Li, Qizhan Liu, Cheng Cheng, Jinsong Zhang, Hao Wu. (2026) H3K18 lactylation-regulated ATG10 is involved in the acute respiratory distress syndrome induced by acute exposure to hydrogen sulfide through activation of autophagy in lung epithelial cells. JOURNAL OF HAZARDOUS MATERIALS, [PMID:] [10.1016/j.jhazmat.2026.142316] |