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· · COA & SDS available for every product · Same-day shipping on in-stock items TCS PIM-1 1 - ≥98%(HPLC) , CAS No.491871-58-0
Synonyms
SC 204330 | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile
Shipped In
Ice chest + Ice pads
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Synonyms
SC 204330 | 3-Cyano-4-phenyl-6-(3-bromo-6-hydroxy)phenyl-2(1H)-pyridone | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1, 2-dihydropyridine-3-carbonitrile
Specifications & Purity
≥98%(HPLC)
Biochemical and Physiological Mechanisms
ATP-competitive Pim-1 kinase inhibitor that displays selectivity over Pim-2 and MEK1/2 (IC50values are 50, > 20000 and > 20000 nM for Pim-1, Pim-2 and MEK1/2 respectively).
Shipped In
Ice chest + Ice pads
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers Pubchem Sid 504760423 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504760423 Canonical Smiles C1=CC=C(C=C1)C2=C(C(=O)NC(=C2)C3=C(C=CC(=C3)Br)O)C#N IUPAC Name 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1H-pyridine-3-carbonitrile InChIKey SVSYJTYGPLVUOZ-UHFFFAOYSA-N INCHI 1S/C18H11BrN2O2/c19-12-6-7-17(22)14(8-12)16-9-13(11-4-2-1-3-5-11)15(10-20)18(23)21-16/h1-9,22H,(H,21,23) Isomeric SMILES C1=CC=C(C=C1)C2=C(C(=O)NC(=C2)C3=C(C=CC(=C3)Br)O)C#N PubChem CID 1235170 Molecular Weight 367.2
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Class Pyridines and derivatives Subclass Phenylpyridines Intermediate Tree Nodes Not available Direct Parent Phenylpyridines Alternative Parents P-bromophenols 3-pyridinecarbonitriles Pyridinones 1-hydroxy-2-unsubstituted benzenoids Bromobenzenes Dihydropyridines Aryl bromides Heteroaromatic compounds Lactams Nitriles Azacyclic compounds Organopnictogen compounds Organic oxides Organobromides Organooxygen compounds Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents 2-phenylpyridine - 4-phenylpyridine - 4-halophenol - 4-bromophenol - 3-pyridinecarbonitrile - Bromobenzene - Dihydropyridine - Halobenzene - Phenol - 1-hydroxy-2-unsubstituted benzenoid - Pyridinone - Monocyclic benzene moiety - Aryl bromide - Aryl halide - Benzenoid - Hydropyridine - Heteroaromatic compound - Lactam - Azacycle - Nitrile - Carbonitrile - Hydrocarbon derivative - Organohalogen compound - Organobromide - Organic oxide - Organopnictogen compound - Organonitrogen compound - Organooxygen compound - Organic nitrogen compound - Organic oxygen compound - Aromatic heteromonocyclic compound Description This compound belongs to the class of organic compounds known as phenylpyridines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyridine ring through a CC or CN bond. External Descriptors nitrile - ring assembly - pyridone - bromophenol Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
3D Structure Associated Targets(Human) Associated Targets(non-human) Mechanisms of Action Certificates（CoA,COO,BSE/TSE and Analysis Chart) Chemical and Physical Properties Solubility Solvent:DMSO, Max Conc. mg/mL: 36.72, Max Conc. mM: 100 Molecular Weight 367.200 g/mol XLogP3 3.300 Hydrogen Bond Donor Count 2 Hydrogen Bond Acceptor Count 3 Rotatable Bond Count 2 Exact Mass 366 Da Monoisotopic Mass 366 Da Topological Polar Surface Area 73.100 Ų Heavy Atom Count 23 Formal Charge 0 Complexity 595.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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