Thioquinapiperifil dihydrochloride - 10mM in DMSO , CAS No.204077-66-7

CAS: 204077-66-7 Cat. No.: T655066 Molecular Weight: 521.51 PubChem CID: 9828075

GRADE & PURITY 10mM in DMSO

Storage

Protected from light,Desiccated,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

Thioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5 , IC 50 of 0.074 nM) inhibitor, is used for sexual enhancement study.

In Vitro

Thioquinapiperifil can be found in dietary supplements. Thioquinapiperifil dihydrochloride (KF31327) (0.1-10 μM) concentration dependently inhibits platelet aggregation. In the absence of nitroglycerin, higher concentrations 1 and 10 μM of Thioquinapiperifil dihydrochloride (KF31327) are required to inhibit platelet aggregation. Thioquinapiperifil dihydrochloride (KF31327) and shows significant increase in cyclic GMP at 10 μM. After 5 min incubation, the mean cyclic GMP levels of Thioquinapiperifil dihydrochloride (KF31327)-treated cells is 0.95±0.17 pmol/10 8 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications

Specifications & Purity

10mM in DMSO

Biochemical and Physiological Mechanisms

Thioquinapiperifil dihydrochloride (KF31327), a potent, selective and non-competitive phosphodiesterase-5 (PDE-5 , IC 50 of 0.074 nM) inhibitor, is used for sexual enhancement study.

Storage

Protected from light, Desiccated, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Names and Identifiers

• Isomeric SMILES: CCN1C2=C(C=C3C(=C2)N=CN=C3NCC4=CC=CC=C4N5CCC(CC5)CO)NC1=S.Cl.Cl
• Alternate CAS: 204077-66-7
• PubChem CID: 9828075
• MeSH Entry Terms: 3-ethyl-8-(2-(4-hydroxymethylpiperidino)benzylamino)-2,3-dihydro-1H-imidazo(4,5-g)quinazoline-2-thione dihydrochloride;KF 31327;KF31327
• Molecular Weight: 521.51