Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 11 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| ALogP | 3.1 |
|---|
| Canonical Smiles | CC1=CC(=O)OC2=C1C=CC(=C2)OC(=O)C3=CC=CO3 |
|---|---|
| IUPAC Name | (4-methyl-2-oxochromen-7-yl) furan-2-carboxylate |
| InChIKey | WVAYNWNBGPUATF-UHFFFAOYSA-N |
| INCHI | 1S/C15H10O5/c1-9-7-14(16)20-13-8-10(4-5-11(9)13)19-15(17)12-3-2-6-18-12/h2-8H,1H3 |
| Isomeric SMILES | CC1=CC(=O)OC2=C1C=CC(=C2)OC(=O)C3=CC=CO3 |
| Molecular Weight | 270.24 |
| Reaxy-Rn | 4503815 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4503815&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Class | Coumarins and derivatives |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Coumarins and derivatives |
| Alternative Parents | 1-benzopyrans Furoic acid esters Pyranones and derivatives Benzenoids Heteroaromatic compounds Lactones Carboxylic acid esters Oxacyclic compounds Monocarboxylic acids and derivatives Organooxygen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Coumarin - Benzopyran - 1-benzopyran - Furoic acid ester - Furoic acid or derivatives - Pyranone - Pyran - Benzenoid - Furan - Heteroaromatic compound - Lactone - Carboxylic acid ester - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Oxacycle - Organoheterocyclic compound - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Organic oxide - Aromatic heteropolycyclic compound |
| Description | This compound belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). |
| External Descriptors | Not available |
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Molecular Weight | 270.240 g/mol |
|---|---|
| XLogP3 | 3.100 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 3 |
| Exact Mass | 270.053 Da |
| Monoisotopic Mass | 270.053 Da |
| Topological Polar Surface Area | 65.700 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 442.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Kechun Chen, Bingtian Xu, Xuan Xiao, Lu Long, Qian Zhao, Zicen Fang, Xingxing Tu, Jiakang Wang, Jiangping Xu, Haitao Wang. (2023) Involvement of CKS1B in the anti-inflammatory effects of cannabidiol in experimental stroke models. EXPERIMENTAL NEUROLOGY, [PMID:38104887] [10.1016/j.expneurol.2023.114654] |
| 2. Shi Jiachen, Ma Qiuling, Su Wenting, Liu Congyan, Zhang Huangqin, Liu Yuping, Li Xiaoqi, Jiang Xi, Ge Chang, Kong Fei, Chen Yan, Qu Ding. (2023) Effervescent cannabidiol solid dispersion-doped dissolving microneedles for boosted melanoma therapy via the “TRPV1-NFATc1-ATF3” pathway and tumor microenvironment engineering. Biomaterials Research, 27 (1): (1-15). [PMID:37198657] [10.1186/s40824-023-00390-x] |
| 3. Qunfang Yang, Tao Liu, Haiping Zheng, Zechen Zhou, Yan Huang, Honglin Jia, Shixiang Fu, Xuan Zhang, Haigang Zhang, Ya Liu, Xiaohong Chen, Wenjun Shan. (2022) A nanoformulation for immunosuppression reversal and broad-spectrum self-amplifying antitumor ferroptosis-immunotherapy. BIOMATERIALS, [PMID:36502663] [10.1016/j.biomaterials.2022.121936] |
| 4. Xu Bing-tian, Li Meng-fan, Chen Ke-chun, Li Xing, Cai Ning-bo, Xu Jiang-ping, Wang Hai-tao. (2022) Mitofusin-2 mediates cannabidiol-induced neuroprotection against cerebral ischemia in rats. ACTA PHARMACOLOGICA SINICA, 44 (3): (499-512). [PMID:36229600] [10.1038/s41401-022-01004-3] |
| 5. Yongzhou Yu, Zuxiao Yang, Baohua Jin, Xia Qin, Xiaoque Zhu, Jiahui Sun, Lifang Huo, Ri Wang, Yongyun Shi, Zhanfeng Jia, Yun Stone Shi, Shifeng Chu, Dezhi Kong, Wei Zhang. (2020) Cannabidiol inhibits febrile seizure by modulating AMPA receptor kinetics through its interaction with the N-terminal domain of GluA1/GluA2. PHARMACOLOGICAL RESEARCH, [PMID:32805354] [10.1016/j.phrs.2020.105128] |
| 6. Weize Diao, Chuangxin Zhou, Zhiheng Zhang, Yifan Cao, Yuxin Li, Junnan Tang, Guozhen Liu. (2024) EGaIn-Modified ePADs for Simultaneous Detection of Homocysteine and C-Reactive Protein in Saliva toward Early Diagnosis of Cardiovascular Disease. ACS Sensors, [PMID:39031767] [10.1021/acssensors.4c01306] |
| 7. Xuan Zhang, Xiangzhou Yi, Xia Gao, Yongcheng Li, Xuanri Shen. (2024) Liver-Targeted Nanoparticles Loaded with Cannabidiol Based on Redox Response for Effective Alleviation of Acute Liver Injury. Foods, 13 (15): (2464). [PMID:39123655] [10.3390/foods13152464] |
| 8. Chuangxin Zhou, Zhiheng Zhang, Yuan Gao, Weize Diao, Siyi Zou, Jun Zhu, Jiangtao Xu, Guozhen Liu. (2025) Formation of Covalent Ga-C Bonds on Liquid Metal Nanoparticles with Enhanced Stability and Anti-Oxidation. Nanoscale, [PMID:41105123] [10.1039/D5NR03476K] |
| 9. Xuan Zhang, Xia Gao, Xiangzhou Yi, Hui Yu, Mingyang Shao, Yongcheng Li, Xuanri Shen. (2024) Multi-targeting inulin-based nanoparticles with cannabidiol for effective prevention of ulcerative colitis. Materials Today Bio, [PMID:38318477] [10.1016/j.mtbio.2024.100965] |
| 10. Jifan Chen, Xuhua Li, Xiangyu Li, Jing Wu, Xiaoli Han, Haihua Wang, Dong Yang. (2025) A ratiometric molecularly imprinted electrochemical sensor based on fluorine-doped ferric oxyhydroxide nanorods for highly sensitive detection of carbendazim. ANALYTICA CHIMICA ACTA, [PMID:41513379] [10.1016/j.aca.2025.344854] |
| 11. Qurat Ul Ain Haidery, Bo Han, Rashid Saeed, Chenyue Yan, Xingyuan Ma, Wenyun Zheng. (2026) Matrix-dependent degradation kinetics and impurity fingerprinting of cannabidiol (CBD) in polymeric and lipid preservation systems. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:] [10.1016/j.jpba.2026.117464] |