5'-O-TBDMS-dA - ≥98% , CAS No.51549-30-5

CAS: 51549-30-5 Cat. No.: O646516 Molecular Weight: 365.50 PubChem CID: 10320127

GRADE & PURITY ≥98%

Synonyms

AKOS030589348 | Adenosine, 2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]- | DTXSID10438072 | MS-25844 | (2R,3S,5R)-5-(6-Amino-9H-purin-9-yl)-2-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-3-ol | 5'-O-TBDMS-dA | HY-138599 | PD157771 | SCHEMBL17

Storage

Protected from light,Store at -80°C

Shipped In

Dry ice packs + Cold packs

Overview

5'-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.

Form:Solid

Specifications

Synonyms

AKOS030589348 | Adenosine, 2'-deoxy-5'-O-[(1, 1-dimethylethyl)dimethylsilyl]- | DTXSID10438072 | MS-25844 | (2R, 3S, 5R)-5-(6-Amino-9H-purin-9-yl)-2-(((tert-butyldimethylsilyl)oxy)methyl)tetrahydrofuran-3-ol | 5'-O-TBDMS-dA | HY-138599 | PD157771 | SCHEMBL17

Specifications & Purity

≥98%

Biochemical and Physiological Mechanisms

5'-O-TBDMS-dA is a modified nucleoside and can be used to synthesize DNA or RNA.

Storage

Protected from light, Store at -80°C

Shipped In

Dry ice packs + Cold packs

This product requires cold chain shipping. Ground and other economy services are not available.

Purity

≥98%

Names and Identifiers

• Canonical Smiles: CC(C)(C)[Si](C)(C)OCC1C(CC(O1)N2C=NC3=C(N=CN=C32)N)O
• IUPAC Name: (2R,3S,5R)-5-(6-aminopurin-9-yl)-2-[[tert-butyl(dimethyl)silyl]oxymethyl]oxolan-3-ol
• InChIKey: HGLRBQHXIBHZTD-QJPTWQEYSA-N
• INCHI: 1S/C16H27N5O3Si/c1-16(2,3)25(4,5)23-7-11-10(22)6-12(24-11)21-9-20-13-14(17)18-8-19-15(13)21/h8-12,22H,6-7H2,1-5H3,(H2,17,18,19)/t10-,11+,12+/m0/s1
• Isomeric SMILES: CC(C)(C)[Si](C)(C)OC[C@@H]1[C@H](C[C@@H](O1)N2C=NC3=C(N=CN=C32)N)O
• Alternate CAS: 51549-30-5
• PubChem CID: 10320127
• Molecular Weight: 365.50

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Nucleosides, nucleotides, and analogues
    • Class Purine nucleosides
      • Subclass Purine 2'-deoxyribonucleosides

• Kingdom: Organic compounds
• Superclass: Nucleosides, nucleotides, and analogues
• Class: Purine nucleosides
• Subclass: Purine 2'-deoxyribonucleosides
• Intermediate Tree Nodes: Not available
• Direct Parent: Purine 2'-deoxyribonucleosides
• Alternative Parents: 6-aminopurines Aminopyrimidines and derivatives N-substituted imidazoles Imidolactams Trialkylheterosilanes Oxolanes Heteroaromatic compounds Silyl ethers Secondary alcohols Oxacyclic compounds Organic metalloid salts Azacyclic compounds Primary amines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Purine 2'-deoxyribonucleoside - 6-aminopurine - Imidazopyrimidine - Purine - Aminopyrimidine - N-substituted imidazole - Imidolactam - Pyrimidine - Trialkylheterosilane - Heteroaromatic compound - Azole - Imidazole - Oxolane - Silyl ether - Secondary alcohol - Organoheterocyclic compound - Organic metalloid salt - Azacycle - Oxacycle - Organoheterosilane - Alcohol - Organic oxygen compound - Primary amine - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Organic metalloid moeity - Organic nitrogen compound - Amine - Organosilicon compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as purine 2'-deoxyribonucleosides. These are compounds consisting of a purine linked to a ribose which lacks a hydroxyl group at position 2.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: DMSO : 100 mg/mL (273.60 mM; Need ultrasonic)
• Molecular Weight: 365.500 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 365.188 Da
• Monoisotopic Mass: 365.188 Da
• Topological Polar Surface Area: 108.000 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 475.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

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