Bicinchoninic acid disodium salt(BCA) - Moligand™, ≥98% , CAS No.979-88-4

CAS: 979-88-4 Cat. No.: B107658 Molecular Weight: 388.28 (anhydrous basis) EC Number: 629-761-2 PubChem CID: 164763

GRADE & PURITY Moligand™, ≥98%

Synonyms

BCA | B5838 | BCADisodium | B4509 | AKOS015951447 | Bicinchoninic Acid Disodium Salt [for Protein Research] | DISODIUM [2,2'-BIQUINOLINE]-4,4'-DICARBOXYLATE | disodium;2-(4-carboxylatoquinolin-2-yl)quinoline-4-carboxylate | (2,2'-Biquinoline)-4,4'-dicarbo

Storage

Store at 2-8°C

Shipped In

Wet ice

Overview

For the determination of protein concentration. 

• Bicinchoninic acid disodium salt hydrate has been used to monitor the levels of reducing sugars, thereby helping in the detection of chitinases.

• It has also been used to determine the amount of cellulose reducing ends (micromoles/g cellulose). 

• It has been used for determining protein concentration.

Specifications

Synonyms

BCA | B5838 | BCADisodium | B4509 | AKOS015951447 | Bicinchoninic Acid Disodium Salt [for Protein Research] | DISODIUM [2, 2'-BIQUINOLINE]-4, 4'-DICARBOXYLATE | disodium;2-(4-carboxylatoquinolin-2-yl)quinoline-4-carboxylate | (2, 2'-Biquinoline)-4, 4'-dicarbo

Specifications & Purity

Moligand™, ≥98%

Biochemical and Physiological Mechanisms

Bicinchoninic acid is used for the determination of protein concentration. It is responsible for the making of intense purple complex with cuprous ion (Cu+), in presence of alkaline conditions. The amount of Cu+ is in relation with the protein concentrati

Storage

Store at 2-8°C

Shipped In

Wet ice

This product requires cold chain shipping. Ground and other economy services are not available.

Grade

Moligand™

Action Type

INHIBITOR

Note

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Purity

≥98%

Names and Identifiers

• Pubchem Sid: 488188374
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488188374
• Canonical Smiles: O.[Na+].[Na+].[O-]C(=O)c1cc(nc2ccccc12)-c3cc(C([O-])=O)c4ccccc4n3
• IUPAC Name: disodium;2-(4-carboxylatoquinolin-2-yl)quinoline-4-carboxylate
• InChIKey: AUPXFICLXPLHBB-UHFFFAOYSA-L
• INCHI: 1S/C20H12N2O4.2Na/c23-19(24)13-9-17(21-15-7-3-1-5-11(13)15)18-10-14(20(25)26)12-6-2-4-8-16(12)22-18;;/h1-10H,(H,23,24)(H,25,26);;/q;2*+1/p-2
• Isomeric SMILES: C1=CC=C2C(=C1)C(=CC(=N2)C3=NC4=CC=CC=C4C(=C3)C(=O)[O-])C(=O)[O-].[Na+].[Na+]
• PubChem CID: 164763
• Molecular Weight: 388.28 (anhydrous basis)

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Class Quinolines and derivatives
      • Subclass Quinoline carboxylic acids

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Class: Quinolines and derivatives
• Subclass: Quinoline carboxylic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Quinoline carboxylic acids
• Alternative Parents: Bipyridines and oligopyridines Pyridinecarboxylic acids Dicarboxylic acids and derivatives Benzenoids Heteroaromatic compounds Carboxylic acid salts Carboxylic acids Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Quinoline-4-carboxylic acid - Bipyridine - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Dicarboxylic acid or derivatives - Benzenoid - Pyridine - Heteroaromatic compound - Carboxylic acid salt - Carboxylic acid derivative - Carboxylic acid - Azacycle - Organic alkali metal salt - Organic nitrogen compound - Organic zwitterion - Organic salt - Organic sodium salt - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
• Description: This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mechanisms of Action

Chemical and Physical Properties

• Solubility: Soluble in water. 0.5% sodium bicarbonate: 50 mg/mL
• Sensitivity: heat sensitive
• Molecular Weight: 388.300 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 388.044 Da
• Monoisotopic Mass: 388.044 Da
• Topological Polar Surface Area: 106.000 Ų
• Heavy Atom Count: 28
• Formal Charge: 0
• Complexity: 495.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

References

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