Enfortumab vedotin-ejfv (anti-Nectin-4) - Primary antibody, specific to NECTIN, >90% (SDS-PAGE&SEC), Human IgG1, Antibody of nectin cell adhesion molecule 4, Antibody of nectin cell adhesion molecule 4

CAS: 1346452-25-2 Cat. No.: Ab175528
AVAILABLE TO ORDER
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human, Mouse
Isotype
Human IgG1
Conjugation
MC-VC-PAB-MMAE
 ·  off list, applied to all prices below.
Size
Status
Price
Qty
100μg
Ab175528-100μg
10
$301.90
1mg
Ab175528-1mg
4
$1,509.90
5mg
Ab175528-5mg
1
$3,775.90
10mg
Ab175528-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
$6,059.90
Enter a quantity for the sizes you want to add.
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Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Overview

Enfortumab vedotin-ejfv (anti-Nectin-4) is an antibody-drug conjugate (ADC) composed of an fully human anti-Nectin-4 IgG1 kappa monoclonal antibody (AGS-22C3), conjugated to Monomethyl Auristatin E (MMAE), via a protease-cleavable maleimidocaproyl-valyl-citrullinyl-p-aminobenzyloxycarbonyl. Enfortumab vedotin-ejfv (anti-Nectin-4) has the potential for use in research of urothelial carcinoma.
Purity
>90% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Enfortumab vedotin-ejfv (anti-Nectin-4) - Primary antibody, specific to NECTIN, >90% (SDS-PAGE&SEC), Human IgG1, Antibody of nectin cell adhesion molecule 4
Synonyms
DKFZp686K05193 antibody | EDSS1 antibody | Ig superfamily receptor LNIR antibody | Nectin 4 antibody | Nectin-4 antibody | poliovirus receptor-related 4 antibody | Processed poliovirus receptor-related protein 4 antibody | PRR4 antibody | pvrl4 antibody |
Specifications & Purity
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Host species
Human
Specificity
NECTIN
Conjugation
MC-VC-PAB-MMAE
Grade
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Action Type
ANTIBODY
Mechanism of action
Antibody of nectin cell adhesion molecule 4
Isotype
Human IgG1
Light Chain Type
kappa
SDS-PAGE
143.9 kDa
Purification Method
Protein A purified
Purity
>90% (SDS-PAGE&SEC)
Concentration
See COA
CAS
1346452-25-2
Storage and Shipping
Shape
Liquid
Storage
Store at -80°C,Avoid repeated freezing and thawing
Shipped In
Dry ice packs + Cold packs
Stability And Storage
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Images

Enfortumab vedotin-ejfv (anti-Nectin-4) (Ab175528) - ELISA
Immobilized Recombinant Human Nectin-4 protein (rp183631) at 1.0 μg/mL can bind Enfortumab vedotin-ejfv (anti-Nectin-4) (Ab175528) with the EC50 of 17.59 ng/mL.

Enfortumab vedotin-ejfv (anti-Nectin-4) (Ab175528) - SEC
The purity of Enfortumab vedotin-ejfv (anti-Nectin-4) (Ab175528) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Associated Targets(Human)
NECTIN4 Tclin Nectin-4 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mechanisms of Action
Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0607449Certificate of AnalysisApr 07, 2026 Ab175528
ZJ24F0607450Certificate of AnalysisApr 07, 2026 Ab175528
ZJ24F0607451Certificate of AnalysisApr 07, 2026 Ab175528
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