Ginsenoside Rg3 - 10mM in DMSO , CAS No.38243-03-7

CAS: 38243-03-7 Cat. No.: G423771 Molecular Weight: 785.01
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GRADE & PURITY 10mM in DMSO
Synonyms
2-[4,5-Dihydroxy-2-[[12-hydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4,4,8,10,14-pentamethyl-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-hydroxymethyl)oxane-3,4,5-triol
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
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Price
Qty
1ml
G423771-1ml
1

$164.90

$241.90
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 6 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Synonyms
2-[4, 5-Dihydroxy-2-[[12-hydroxy-17-(2-hydroxy-6-methylhept-5-en-2-yl)-4, 4, 8, 10, 14-pentamethyl-2, 3, 5, 6, 7, 9, 11, 12, 13, 15, 16, 17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]-6-(hydroxymethyl)oxan-3-yl]oxy-6-hydroxymethyl)oxane-3, 4, 5-triol
Specifications & Purity
10mM in DMSO
Biochemical and Physiological Mechanisms
Natural triterpenoid saponin found in Panax notoginseng . Shows a variety of biological activities. Shows anti-tumor activity and suppresses COX-2 expression. Inhibits brain Na + currents (IC 50 = 32 μM). Modulatory role in neuroinflammation.
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
This product requires cold chain shipping. Ground and other economy services are not available.
Names and Identifiers
Molecular Weight 785.01
Reaxy-Rn 27844255
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=27844255&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificates(CoA,COO,BSE/TSE and Analysis Chart)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Citations of This Product
References
1. Zeng Xiangfeng, Liu Shengyao, Yang Hua, Jia Menglei, Liu Wei, Zhu Wenting.  (2023)  Synergistic anti-tumour activity of ginsenoside Rg3 and doxorubicin on proliferation, metastasis and angiogenesis in osteosarcoma by modulating mTOR/HIF-1α/VEGF and EMT signalling pathways.  JOURNAL OF PHARMACY AND PHARMACOLOGY,      [PMID:37498992] [10.1093/jpp/rgad070]
2. Ren Rongfan, Li Hongli, Jiang Qing, Wang Xing, Chen David Da Yong.  (2022)  Characterization of ginsenoside structural isomers from mixtures using in situ methylation with direct analysis in real-time ionization tandem mass spectrometry.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  415  (5): (887-897).  [PMID:36571591] [10.1007/s00216-022-04482-w]
3. Tianhua Liu, Ling Zuo, Dongqing Guo, Xinlou Chai, Jie Xu, Zhaorui Cui, Zhiyi Wang, Chunying Hou.  (2019)  Ginsenoside Rg3 regulates DNA damage in non-small cell lung cancer cells by activating VRK1/P53BP1 pathway.  BIOMEDICINE & PHARMACOTHERAPY,      [PMID:31629252] [10.1016/j.biopha.2019.109483]
4. Nan Zhao, Mengchun Cheng, Shuai Huang, Dan Liu, Qiang Zhao, Yunpeng Bai, Xiaozhe Zhang.  (2019)  Various Multicharged Anions of Ginsenosides in Negative Electrospray Ionization with QTOF High-Resolution Mass Spectrometry.  JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY,      [PMID:30644055] [10.1007/s13361-018-2089-5]
5. Xiaonan Zhang, Kang Chen, Bo Wei, Xingwang Liu, Zeming Lei, Xizhuang Bai.  (2016)  Ginsenosides Rg3 attenuates glucocorticoid-induced osteoporosis through regulating BMP-2/BMPR1A/Runx2 signaling pathway.  CHEMICO-BIOLOGICAL INTERACTIONS,      [PMID:27387537] [10.1016/j.cbi.2016.07.003]
6. Xinyi Lv, Yuehan Song, Tianhua Liu, Dingdan Zhang, Xinpeng Ye, Qingqing Wang, Rongrong Li, Jiayi Chen, Shujing Zhang, Xue Yu, Chunying Hou.  (2025)  Ginsenoside Rg3 Adjunctively Increases the Efficacy of Gefitinib Against NSCLC by Regulating EGFR Copy Number.  Pharmaceuticals,  18  (7): (1077).  [PMID:40732366] [10.3390/ph18071077]
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