Glycine Hydrochloride - ≥99%(T) , CAS No.6000-43-7

CAS: 6000-43-7 Cat. No.: G156794 Molecular Weight: 111.53 Beilstein Registry Number: 4340 EC Number: 227-841-8

GRADE & PURITY ≥99%(T)

Synonyms

225ZLC74HX | GLYCINE HYDROCHLORIDE [MI] | 2-aminoacetic acid hydrochloride | CCRIS 3355 | F21278 | Glycinehydrochloride | Q27253616 | EINECS 227-841-8 | AS-15481 | FT-0622279 | W-105287 | Glycocoll hydrochloride | UNII-225ZLC74HX | Aminoacetic acid hydroc

Storage

Argon charged,Room temperature

Shipped In

Normal

Overview

Glycine is an inhibitory amino acid neurotransmitter that only acts on receptors which bring out an enhanced chloride conductance. It shows highest concentrations in the spinal cord as compared to elsewhere in the brain. However, it interacts with and allostericaly activates the excitatory receptor N-methyl-D-aspartate (NMDA), thus, resulting in excitatory transmission in brain.

Specifications

Synonyms

225ZLC74HX | GLYCINE HYDROCHLORIDE [MI] | 2-aminoacetic acid hydrochloride | CCRIS 3355 | F21278 | Glycinehydrochloride | Q27253616 | EINECS 227-841-8 | AS-15481 | FT-0622279 | W-105287 | Glycocoll hydrochloride | UNII-225ZLC74HX | Aminoacetic acid hydroc

Specifications & Purity

≥99%(T)

Biochemical and Physiological Mechanisms

Inhibitory neurotransmitter in spinal cord, allosteric regulator of NMDA receptors.

Storage

Argon charged, Room temperature

Shipped In

Normal

Purity

≥99%(T)

Names and Identifiers

• Pubchem Sid: 488182754
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488182754
• Canonical Smiles: C(C(=O)O)N.Cl
• IUPAC Name: 2-aminoacetic acid;hydrochloride
• InChIKey: IVLXQGJVBGMLRR-UHFFFAOYSA-N
• INCHI: 1S/C2H5NO2.ClH/c3-1-2(4)5;/h1,3H2,(H,4,5);1H
• Isomeric SMILES: C(C(=O)O)N.Cl
• RTECS: MC0560000
• Molecular Weight: 111.53
• Beilstein: 4340
• Reaxy-Rn: 3673895
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3673895&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Class Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Class: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Alpha amino acids
• Alternative Parents: Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-amino acid - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organic oxygen compound - Hydrocarbon derivative - Hydrochloride - Primary amine - Organooxygen compound - Organonitrogen compound - Organic nitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Organic oxide - Organopnictogen compound - Aliphatic acyclic compound
• Description: This compound belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Chemical and Physical Properties

• Solubility: Soluble in water (>100 g/L).
• Sensitivity: Moisture sensitive.
• Melt Point(°C): 176-180 °C
• Molecular Weight: 111.530 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 111.009 Da
• Monoisotopic Mass: 111.009 Da
• Topological Polar Surface Area: 63.300 Ų
• Heavy Atom Count: 6
• Formal Charge: 0
• Complexity: 42.900
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

References

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